Results 151 to 159 of about 27,127 (159)

Graded Organ Response and Progression Criteria for Kidney Immunoglobulin Light Chain Amyloidosis.

JAMA Oncology
Importance Kidney light chain (AL) amyloidosis is associated with a risk of progression to kidney replacement therapy (KRT) and death. Several studies have shown that a greater reduction in proteinuria following successful anticlonal therapy is ...
Eli Muchtar, Brendan Wisniowski, Susan Geyer, G. Palladini, P. Milani, G. Merlini, S. Schönland, K. Veelken, Ute Hegenbart, Nelson Leung, A. Dispenzieri, Shaji K. Kumar, E. Kastritis, M. Dimopoulos, Michaela Liedtke, Patricia Ulloa, V. Sanchorawala, R. Szalat, Katharine E Dooley, Heather Landau, Erica Petrlik, Suzanne Lentzsch, A. Coltoff, J. Bladé, M. Cibeira, O. Cohen, Darren Foard, Jullian Gillmore, H. Lachmann, A. Wechalekar, M. Gertz   +30 more
semanticscholar   +1 more source

Rapid Complete Response to Single-Agent Bcl-2 Inhibitor Venetoclax in a Heart-Transplanted Patient with Triple Refractory Immunoglobulin Light-Chain Amyloidosis

Acta Haematologica, 2020
Immunoglobulin light-chain amyloidosis (AL) is a disease with limited treatment options due to the frailty of patients caused by organ damage. Since the clonal plasma cells often contain the cytogenetic aberration t(11;14), the Bcl-2 inhibitor venetoclax
Charlotte Gran, Johanna Borg Bruchfeld, F. Ellin, H. Nahi   +3 more
semanticscholar   +1 more source

Novel challenges in the management of immunoglobulin light chain amyloidosis: from the bench to the bedside

Expert Review of Hematology, 2020
Introduction Immunoglobulin light chain (AL) amyloidosis is one of the most frequent systemic amyloidosis in Western countries. It is caused by a B-cell clone producing a misfolded light chain (LC) that deposits in organs.
M. Basset, M. Nuvolone, G. Palladini, G. Merlini   +3 more
semanticscholar   +1 more source

Bioelectrical impedance vector analysis-derived phase angle predicts survival in patients with systemic immunoglobulin light-chain amyloidosis

Amyloid: Journal of Protein Folding Disorders, 2020
Background: The aim of the present prospective study (ClinicalTrials.gov Identifier: NCT02111538) was to assess the prognostic value of phase angle (PhA), derived from bioimpedance vectorial analysis (BIVA), in patients affected by systemic amyloid light-
R. Caccialanza, E. Cereda, C. Klersy, P. Milani, S. Cappello, V. Martinelli, A. Turri, M. Basset, V. Borioli, M. Nuvolone, M. Caraccia, F. Lavatelli, S. Masi, F. Lobascio, A. Foli, G. Merlini, G. Palladini   +16 more
semanticscholar   +1 more source

Systemic immunoglobulin light chain amyloidosis

Nature Reviews Disease Primers, 2018
G. Merlini, A. Dispenzieri, V. Sanchorawala, S. Schönland, G. Palladini, P. Hawkins, M. Gertz   +6 more
semanticscholar   +1 more source

New criteria for response to treatment in immunoglobulin light chain amyloidosis based on free light chain measurement and cardiac biomarkers: impact on survival outcomes.

Journal of Clinical Oncology, 2012
G. Palladini, A. Dispenzieri, M. Gertz, Shaji K. Kumar, A. Wechalekar, P. Hawkins, S. Schönland, U. Hegenbart, R. Comenzo, E. Kastritis, M. Dimopoulos, A. Jaccard, C. Klersy, G. Merlini   +13 more
semanticscholar   +1 more source

Transcriptional heterogeneity of clonal plasma cells and immune evasion in immunoglobulin light chain amyloidosis

International journal of hematology, 2020
Yujia Wang, Lushuang Xu, Yang Liu, Yuzhe Hu, Qiang Shi, Lixue Jin, Lijun Yang, Pingzhang Wang, Kunshan Zhang, Xiaojun Huang, Q. Ge, Jin Lu   +11 more
semanticscholar   +1 more source

Overuse of organ biopsies in immunoglobulin light chain amyloidosis (AL): the consequence of failure of early recognition

Annals medicus, 2017
Eli Muchtar, A. Dispenzieri, M. Lacy, F. Buadi, P. Kapoor, S. Hayman, W. Gonsalves, R. Warsame, T. Kourelis, R. Chakraborty, S. Russell, J. Lust, Yi Lin, R. Go, S. Zeldenrust, S. Rajkumar, D. Dingli, N. Leung, R. Kyle, Shaji K. Kumar, M. Gertz   +20 more
semanticscholar   +1 more source

Immunoglobulin Light Chain Amyloidosis.

Mayo Clinic proceedings
Mahin Bhatt, D. Jevremovic, S. V. Rajkumar   +2 more
semanticscholar   +1 more source