Results 41 to 50 of about 27,127 (159)

Successful management of refractory pleural effusion due to systemic immunoglobulin light chain amyloidosis by vincristine adriamycin dexamethasone chemotherapy: a case report

Journal of Medical Case Reports, 2010
Introduction Refractory pleural effusion in systemic immunoglobulin light chain amyloidosis without cardiac decompensation is rarely reported and has a poor prognosis in general (a median survival of 1.6 months).
Mima Akira, Murakami Taichi, Mimura Rokuro, Araki Makoto, Kishi Seiji, Hoshina Azusa, Kondo Makiko, Ikeda Masaki, Nishioka Keisuke, Takeoka Hiroya, Araoka Toshikazu, Nagai Kojiro, Abe Hideharu, Doi Toshio   +13 more
doaj   +1 more source

Breast amyloidosis: a case report [PDF]

, 2016
Amyloidosis is an uncommon disorder characterized by extracellular deposition of abnormal proteins. Breast involvement has rarely been reported and can clinically be misdiagnosed as breast cancer.
Boscaini, Giulia, DE SANTIS, Giorgio, Pignatti, Marco, Tazzioli, Giovanni   +3 more
core   +1 more source

A prospective study of nutritional status in immunoglobulin light chain amyloidosis

Haematologica, 2013
Weight loss is common in systemic immunoglobulin light chain amyloidosis but there are limited data on the impact of nutritional status on outcome.
Prayman T. Sattianayagam, Thirusha Lane, Zoe Fox, Aviva Petrie, Simon D.J. Gibbs, Jennifer H. Pinney, Signe S. Risom, Dorota M. Rowczenio, Ashutosh D. Wechalekar, Helen J. Lachmann, Janet A. Gilbertson, Philip N. Hawkins, Julian D. Gillmore   +12 more
doaj   +1 more source

Concurrent light chain amyloidosis and proximal tubulopathy: Insights into different aggregation behavior—A case report

eJHaem, 2022
Due to differences in the protein folding mechanisms, it is exceedingly rare for amyloid light chain (AL) amyloidosis and monoclonal gammopathy of renal significance (MGRS) to coexist.
Simone Feurstein, Julian Zoller, Constantin Schwab, Sarah Schreiner, Heiko Mundt, Iris Breitkreutz, Brigitte Schneider, Jörg Beimler, Martin Zeier, Rüdiger Waldherr, Stefan Gröschel, Carsten Müller‐Tidow, Stefan O. Schönland, Ute Hegenbart   +13 more
doaj   +1 more source

C-src Enriched Serum Microvesicles Are Generated in Malignant Plasma Cell Dyscrasia [PDF]

, 2013
Plasma cell dyscrasias are immunosecretory disorders that can lead to hematological malignancies such as Multiple Myeloma (MM). MM accounts for 15% of all hematologic cancers, and those diagnosed with MM typically become severely ill and have a low life
Andrea, Zendrini, Caimi, Luigi, DI NOTO, Giuseppe, Paolini, Lucia, Radeghieri, Annalisa, Ricotta, Doris   +5 more
core   +3 more sources

A stepwise data interpretation process for renal amyloidosis typing by LMD-MS

BMC Nephrology, 2022
Backgrounds Systemic amyloidosis is classified according to the deposited amyloid fibril protein (AFP), which determines its best therapeutic scheme. The most common type of AFP found are immunoglobulin light chains.
Ming Ke, Xin Li, Lin Wang, Shuling Yue, Beibei Zhao   +4 more
doaj   +1 more source

Immunoglobulin light chain amyloidosis: 2018 Update on diagnosis, prognosis, and treatment

American journal of hematology/oncology, 2018
Immunoglobulin light chain amyloidosis is a clonal, nonproliferative plasma cell disorder in which fragments of immunoglobulin light or heavy chain are deposited in tissues.
M. Gertz
semanticscholar   +1 more source

An updated AL-Base reveals ranked enrichment of immunoglobulin light chain variable genes in AL amyloidosis

bioRxiv
Background Each monoclonal antibody light chain associated with AL amyloidosis has a unique sequence. Defining how these sequences lead to amyloid deposition could facilitate faster diagnosis and lead to new treatments.
Gareth J Morgan, Allison N. Nau, Sherry Wong, Brian H Spencer, Yun Shen, Axin Hua, Matthew J. Bullard, V. Sanchorawala, Tatiana Prokaeva   +8 more
semanticscholar   +2 more sources

Incidence and survival in non-hereditary amyloidosis in Sweden [PDF]

, 2012
BACKGROUND: Amyloidosis is a heterogeneous disease caused by deposition of amyloid fibrils in organs and thereby interfering with physiological functions.
Asta Försti, Jan Sundquist, Kari Hemminki, Kristina Sundquist, Xinjun Li   +4 more
core   +1 more source

Cardiac Amyloidosis: Clinical Features, Pathogenesis, Diagnosis, and Treatment [PDF]

Türk Patoloji Dergisi
Cardiac amyloidosis is a type of amyloidosis that deserves special attention as organ involvement significantly worsens the prognosis. Cardiac amyloidosis can be grouped under three main headings: immunoglobulin light chain (AL) amyloidosis that is ...
Asuman ARGON, Deniz NART, Funda YILMAZ BARBET   +2 more
doaj   +1 more source