Results 31 to 40 of about 5,095,980 (121)

Successful management of refractory pleural effusion due to systemic immunoglobulin light chain amyloidosis by vincristine adriamycin dexamethasone chemotherapy: a case report

Journal of Medical Case Reports, 2010
Introduction Refractory pleural effusion in systemic immunoglobulin light chain amyloidosis without cardiac decompensation is rarely reported and has a poor prognosis in general (a median survival of 1.6 months).
Mima Akira, Murakami Taichi, Mimura Rokuro, Araki Makoto, Kishi Seiji, Hoshina Azusa, Kondo Makiko, Ikeda Masaki, Nishioka Keisuke, Takeoka Hiroya, Araoka Toshikazu, Nagai Kojiro, Abe Hideharu, Doi Toshio   +13 more
doaj   +1 more source

A Case of Primary Amyloidosis Involving Liver, Stomach, Intestines, and Heart without Evident Kidney Involvement

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2022
Aim. Systemic amyloidosis caused by the synthesis and deposition of immunoglobulin light chains (AL amyloidosis) is a relatively rare disease that involves heart, kidneys, peripheral nervous system, gastrointestinal tract, and has a large number of ...
L. S. Kholopov, N. B. Gubegrits, O. A. Dyadyk, Yu. E. Chirkov, Yu. V. Tsohoyeva   +4 more
doaj   +1 more source

Daratumumab for Immunoglobulin Light Chain Amyloidosis

, 2021
Immunoglobulin light chain (AL) amyloidosis is characterized by small, indolent plasma cell clones that uniformly demonstrate high expression of CD38 surface molecule and produce toxic, free light chains.
Theodorakakou, Foteini, Dimopoulos, Meletios A., Kastritis, Efstathios   +2 more
core   +1 more source

A prospective study of nutritional status in immunoglobulin light chain amyloidosis

Haematologica, 2013
Weight loss is common in systemic immunoglobulin light chain amyloidosis but there are limited data on the impact of nutritional status on outcome.
Prayman T. Sattianayagam, Thirusha Lane, Zoe Fox, Aviva Petrie, Simon D.J. Gibbs, Jennifer H. Pinney, Signe S. Risom, Dorota M. Rowczenio, Ashutosh D. Wechalekar, Helen J. Lachmann, Janet A. Gilbertson, Philip N. Hawkins, Julian D. Gillmore   +12 more
doaj   +1 more source

Producing amyloid fibrils in vitro: A tool for studying AL amyloidosis

Biochemistry and Biophysics Reports, 2023
Amyloid light-chain (AL) amyloidosis is the second most common form of systemic amyloidosis which is characterized by a high level of mortality and no effective treatment to remove fibril deposition.
Daria V. Sizova, Steve Raiker, Deaneira Lakheram, Vishwanatha Rao, Andrew Proffitt, Yazen Jmeian, Walter Voegtli, Melissa Batonick   +7 more
doaj   +1 more source

Hereditary systemic immunoglobulin light-chain amyloidosis

, 2015
Several members of a family died from renal failure as a result of systemic amyloidosis. Extensive studies to detect previously documented gene mutations associated with amyloidosis failed to identify a causative factor.
Liepnieks, Juris J., Kluve-Beckerman, Barbara, Benson, Merrill D.   +2 more
core   +1 more source

Differences in immunoglobulin light chain species found in urinary exosomes in light chain amyloidosis (Al). [PDF]

, 2012
Renal involvement is a frequent consequence of plasma cell dyscrasias. The most common entities are light chain amyloidosis, monoclonal immunoglobulin deposition disease and myeloma cast nephropathy.
Charlesworth M. Cristine, Marie C. Hogan (157476), Leung Nelson, Gong Xun, Hogan Marie C., Xun Gong (82361), Bing Q Huang, Marina Ramirez-Alvarado, Xun Gong, Madden Benjamin J., Nelson Leung, Ramirez-Alvarado Marina, M Cristine Charlesworth, Bing Q. Huang (157470), Benjamin J Madden, Ward Christopher J., Marina Ramirez-Alvarado (157462), Christopher J Ward, Marie C Hogan, Christopher J. Ward (157466), Nelson Leung (157485), Benjamin J. Madden (157479), M. Cristine Charlesworth (157482), Huang Bing Q.   +23 more
core   +1 more source

A stepwise data interpretation process for renal amyloidosis typing by LMD-MS

BMC Nephrology, 2022
Backgrounds Systemic amyloidosis is classified according to the deposited amyloid fibril protein (AFP), which determines its best therapeutic scheme. The most common type of AFP found are immunoglobulin light chains.
Ming Ke, Xin Li, Lin Wang, Shuling Yue, Beibei Zhao   +4 more
doaj   +1 more source

Immunoglobulin Light Chain Amyloidosis

Clinical Case Reports
Symmetric, purpuric hand nodules and macroglossia prompted skin biopsy revealing immunoglobulin light chain amyloidosis, leading to the diagnosis of multiple myeloma.
Justin Lyon, Ashley Khouri, Katheryn A. Bell, Jamie Zussman   +3 more
doaj   +1 more source

Cardiac Amyloidosis: Clinical Features, Pathogenesis, Diagnosis, and Treatment [PDF]

Türk Patoloji Dergisi
Cardiac amyloidosis is a type of amyloidosis that deserves special attention as organ involvement significantly worsens the prognosis. Cardiac amyloidosis can be grouped under three main headings: immunoglobulin light chain (AL) amyloidosis that is ...
Asuman ARGON, Deniz NART, Funda YILMAZ BARBET   +2 more
doaj   +1 more source