Results 11 to 20 of about 5,095,980 (121)
Localized Immunoglobulin Light-Chain Amyloidosis of the Ulnar Nerve [PDF]
Case Reports in Neurology, 2021 Amyloidosis is a disorder caused by extracellular tissue deposition of insoluble fibrils. Amyloidosis can be divided into systemic or localized disease. Primary systemic amyloidosis is a multisystem disease caused by the deposition of amyloid in various ...
Shinsuke Morisaki +5 more
doaj +2 more sources
Localized Lymph Node Light Chain Amyloidosis [PDF]
Case Reports in Hematology, 2015 Immunoglobulin-derived light chain amyloidosis can occasionally be associated with localized disease. We present a patient with localized lymph node light chain amyloidosis without an underlying monoclonal protein or lymphoproliferative disorder and ...
Binod Dhakal +3 more
doaj +2 more sources
Bilateral atrial appendage thrombosis in light chain cardiac amyloidosis: a case report
Frontiers in Cardiovascular MedicineLight chain cardiac amyloidosis (AL-CA) is a severe and progressively infiltrative disease caused by the deposition of misfolded monoclonal immunoglobulin light chains in the myocardial extracellular space.
Haiyan Jia +4 more
doaj +2 more sources
Cutaneous light chain amyloidosis with multiple myeloma: A concise review
Hematology/Oncology and Stem Cell Therapy, 2019 Objective/Background: Cutaneous immunoglobulin (Ig) amyloid light-chain (AL) amyloidosis associated with overt multiple myeloma (MM) is rare and optimal treatment is not well defined.
Mirela Andrei, Jen Chin Wang
doaj +2 more sources
eJHaem, 2022 Due to differences in the protein folding mechanisms, it is exceedingly rare for amyloid light chain (AL) amyloidosis and monoclonal gammopathy of renal significance (MGRS) to coexist.
Simone Feurstein +13 more
doaj +2 more sources
Recent advances in understanding and treating immunoglobulin light chain amyloidosis [version 1; referees: 2 approved] [PDF]
F1000Research, 2018 Immunoglobulin (Ig) light chain (AL) amyloidosis is a clonal plasma cell disorder characterized by misfolded Ig light chain deposition in vital organs of the body, resulting in proteotoxicity and organ dysfunction.
Talha Badar +2 more
doaj +2 more sources
Case Reports in Gastrointestinal Medicine, 2021 Multiple myeloma is a type of plasma cell neoplasm that produces monoclonal immunoglobulin. Multiple myeloma is known to cause immunoglobulin light-chain (AL) amyloidosis, which frequently involves the kidney and heart.
Katsuya Endo +15 more
doaj +2 more sources
Virtual Screening for Promising Kinetic Stabilizers of Light Chains in Immunoglobulin Light Chain Amyloidosis Through Drug Repurposing [PDF]
, 2023 In immunoglobulin light chain amyloidosis, unstable immunoglobulin light chains aggregate as amyloid fibrils in organs, leading to organ failure and death in more than 50% of untreated patients. Research by Morgan et al. (Morgan, G. J. et.
Jonas, Jeppesen +3 more
core +2 more sources
Localized Lymph Node Light Chain Amyloidosis [PDF]
, 2020 The prognosis of systemic amyloid light chain (AL) amyloidosis is generally poor, hence requiring chemotherapy or hematopoietic stem cell transplantation, while the prognosis of localized AL amyloidosis without an abnormal monoclonal immunoglobulin light
Yamashita, Taro +4 more
core +2 more sources
Immunoglobulin light-chain amyloidosis mimicking bulbar amyotrophic lateral sclerosis
, 2023 Immunoglobulin light-chain amyloidosis mimicking bulbar amyotrophic lateral ...
Antoine Pegat (16266978) +1 more
core +1 more source