Results 31 to 40 of about 411,227 (271)
Proteolysis of rabbit immunoglobulin M by papain [PDF]
Biochemical Journal, 1974 1. Digestion of rabbit immunoglobulin M (IgM) by papain for 5h, in the absence of reducing agent, gives Fabμ and Fc5μ fragments in high yield. Shorter periods give fragment Fc5μ with one or more Fabμ fragments still attached. 2. Reducing agent in the absence of a denaturant cleaves rabbit IgM into half-subunits, each containing one μ chain and one ...
Barbara M. McIlroy, George T. Stevenson
openaire +3 more sources
Immunoglobulin M Monoclonal Gammopathies of Clinical Significance
Frontiers in Oncology, 2022 Immunoglobulin M monoclonal gammopathy of undetermined significance (MGUS) comprises 15-20% of all cases of MGUS. IgM MGUS is distinct from other forms of MGUS in that the typical primary progression events include Waldenstrom macroglobulinaemia and ...
Louis-Pierre Girard +6 more
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Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2020 Background: Waldenstrom macroglobulinemia (WM) is a rare mature B cell Neoplasm, characterized by monoclonal Immunoglobulin M (IgM) in the serum and lymphoplasmacytic infiltration in the bone marrow.
Gautam Kumar Vasnik +3 more
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An Ising-Like model for protein mechanical unfolding [PDF]
Phys. Rev. Lett. 98, 148102 (2007), 2006 The mechanical unfolding of proteins is investigated by extending the Wako-Saito-Munoz-Eaton model, a simplified protein model with binary degrees of freedom, which has proved successful in describing the kinetics of protein folding. Such a model is generalized by including the effect of an external force, and its thermodynamics turns out to be exactly
arxiv +1 more source
Waldenstrom Macroglobulinemia Complicated with Hyperviscosity Syndrome
Central Asian Journal of Medical Sciences, 2015 Objectives: Waldenstrom Macroglobulinemia (WM) is a malignant disease of the B lymphocytes. We report on a patient in Mongolia having WM complicated with hyperviscosity syndrome.
Narangerel Jigjidkhorol +9 more
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Biosynthesis of the carbohydrate portions of immunoglobulin M [PDF]
Biochemical Journal, 1971 Incorporations of radioactive mannose, galactose and fucose into MOPC 104E mouse plasma-cell tumour suspensions suggest a stepwise addition of carbohydrate residues to immunoglobulin M (IgM) during the process of secretion. Mannose and glucosamine residues are added at an early stage, whereas galactose and fucose are added just before, or at the time ...
Fritz Melchers, R. M. E. Parkhouse
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Facial Palsy and Lyme Borreliosis
Pediatric Neurology Briefs, 1997 The value of CSF examinations for intrathecal antibody production to Borrelia burgdorferi in the diagnosis of neuroborreliosis in children with peripheral facial palsy (PFP) was examined at the University Children’s Hospital of Zurich, Switzerland.
J Gordon Millichap
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Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA
Frontiers in Immunology, 2023 IntroductionMZB1 is an endoplasmic reticulum residential protein preferentially expressed in plasma cells, marginal zone and B1 B cells. Recent studies on murine B cells show that it interacts with the tail piece of IgM and IgA heavy chain and promotes ...
Benjamin Geary +9 more
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Evaluation of the Immunomodulatory Effect of an Organometallic Formulation of Laghumalini Vasant by using Cell Culture: A Research Protocol [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: The immune system serves as the body’s defence mechanism and aids in maintaining homeostasis by defending against infections and foreign bodies.
Anita Wanjari, Bharat Rathi, Amit Naik
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OLGA: fast computation of generation probabilities of B- and T-cell receptor amino acid sequences and motifs [PDF]
Bioinformatics 35 (17) 2974--2981 (2019), 2018 Motivation: High-throughput sequencing of large immune repertoires has enabled the development of methods to predict the probability of generation by V(D)J recombination of T- and B-cell receptors of any specific nucleotide sequence. These generation probabilities are very non-homogeneous, ranging over 20 orders of magnitude in real repertoires.
arxiv +1 more source