Results 1 to 10 of about 70,538 (300)

Immunoglobulin replacement therapy in secondary hypogammaglobulinemia [PDF]

Frontiers in Immunology, 2014
Immunoglobulin (Ig) replacement therapy dramatically changed the clinical course of primary hypogammaglobulinemias, significantly reducing the incidence of infectious events.
Nicolò eCompagno, Giacomo eMalipiero, Francesco eCinetto, Carlo eAgostini   +3 more
doaj   +5 more sources

Primary Immune Deficiency: Patients’ Preferences for Replacement Immunoglobulin Therapy [PDF]

Frontiers in Immunology, 2022
PurposeImmunoglobulin (Ig) replacement therapy is an important life-saving treatment modality for patients with primary antibody immune deficiency disorders (PAD).
Juan Marcos Gonzalez, Mark Ballow, Mark Ballow, Angelyn Fairchild, Michael Chris Runken   +4 more
doaj   +4 more sources

To substitute or not? A systematic review of immunoglobulin replacement therapy in multiple myeloma patients treated with bispecific antibodies. [PDF]

Front Immunol
Bispecific antibodies are a novel class of immunotherapies that have demonstrated high response rates in heavily pretreated patients with multiple myeloma.
Paulsen JS, Slørdahl TS.
europepmc   +2 more sources

Cytokine dysregulation despite immunoglobulin replacement therapy in common variable immunodeficiency (CVID). [PDF]

Front Immunol, 2023
IntroductionCommon variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency. CVID is a heterogeneous disorder with a presumed multifactorial etiology. Intravenous or subcutaneous immunoglobulin replacement therapy (IgRT)
Poto R, Pecoraro A, Ferrara AL, Punziano A, Lagnese G, Messuri C, Loffredo S, Spadaro G, Varricchi G.   +8 more
europepmc   +2 more sources

Immunoglobulin Replacement Therapy: Insights into Multiple Myeloma Management. [PDF]

Cancers (Basel)
Immunoglobulin (Ig) replacement therapy (IgRT) consists of the administration of low-dose human polyclonal Igs for the treatment of primary and secondary hypogammaglobulinemia that are associated with recurrent infections and immune dysfunction. IgRT restores physiological antibody levels and induces an immunomodulatory effect by strengthening immune ...
Saltarella I, Altamura C, Solimando AG, D'Amore S, Ria R, Vacca A, Desaphy JF, Frassanito MA.   +7 more
europepmc   +4 more sources

Use of Immunoglobulin Replacement Therapy in Clinical Practice: A Review. [PDF]

J Immunother Precis Oncol
Immunoglobulins (Igs) are produced by B lymphocytes and play a key role in humoral immunity. Igs are classified into five isotypes (IgG, IgA, IgM, IgE, and IgD). Their primary function is to recognize and bind to foreign antigens.
Ahmed J, Choi Y, Ko T, Lim J, Hajjar J.
europepmc   +2 more sources

Controversies about immunoglobulin replacement therapy in HSCT recipients with hypogammaglobulinemia. [PDF]

Bone Marrow Transplant, 2022
The efficacy of immunoglobulin replacement therapy (IgRT) has been demonstrated for primary immune deficiency diseases and hematological malignancies such as chronic lymphocytic leukemia (CLL) or multiple myeloma with hypogammaglobulinemia. Clinical development of anti-B cell therapies including a monoclonal antibody, bispecific antibody, or chimeric ...
Ohmoto A, Fuji S, Shultes KC, Savani BN, Einsele H.   +4 more
europepmc   +3 more sources

Current Practice and Perspectives on Subcutaneous Immunoglobulin Replacement Therapy in Patients with Primary Antibody Deficiency Among Specialized Nurses in Poland. [PDF]

Nurs Rep
Background/Objectives: Inborn errors of immunity (IEI) encompass various congenital disorders, resulting in immunity defects and recurrent infections. Home-based subcutaneous immunoglobulin replacement therapy (scIgRT) is the best treatment option for ...
Mizera D, Dziedzic R, Drynda A, Matyja-Bednarczyk A, Padjas A, Celińska-Löwenhoff M, Jakieła B, Bazan-Socha S.   +7 more
europepmc   +2 more sources

Effectiveness of immunoglobulin replacement therapy in preventing infections in patients with chronic obstructive pulmonary disease: a systematic review. [PDF]

Allergy Asthma Clin Immunol
Purpose Immunoglobulin replacement therapy is a standard treatment for patients with antibody production deficiencies, which is of interest in patients with chronic obstructive pulmonary disease (COPD).
Kim JJY, Dennett L, Ospina MB, Hicks A, Vliagoftis H, Adatia A.   +5 more
europepmc   +2 more sources

A clinician's guide for administration of high-concentration and facilitated subcutaneous immunoglobulin replacement therapy in patients with primary immunodeficiency diseases. [PDF]

Allergy Asthma Clin Immunol, 2022
Immunoglobulin replacement therapy is the standard-of-care treatment for patients with primary immunodeficiency diseases who have impaired antibody production and function.
Epland K, Suez D, Paris K.
europepmc   +2 more sources