Results 21 to 30 of about 2,930,894 (275)

Immunoglobulin Replacement Therapy: Insights into Multiple Myeloma Management. [PDF]

Cancers (Basel)
Immunoglobulin (Ig) replacement therapy (IgRT) consists of the administration of low-dose human polyclonal Igs for the treatment of primary and secondary hypogammaglobulinemia that are associated with recurrent infections and immune dysfunction. IgRT restores physiological antibody levels and induces an immunomodulatory effect by strengthening immune ...
Saltarella I, Altamura C, Solimando AG, D'Amore S, Ria R, Vacca A, Desaphy JF, Frassanito MA.   +7 more
europepmc   +4 more sources

Controversies about immunoglobulin replacement therapy in HSCT recipients with hypogammaglobulinemia. [PDF]

Bone Marrow Transplant, 2022
The efficacy of immunoglobulin replacement therapy (IgRT) has been demonstrated for primary immune deficiency diseases and hematological malignancies such as chronic lymphocytic leukemia (CLL) or multiple myeloma with hypogammaglobulinemia. Clinical development of anti-B cell therapies including a monoclonal antibody, bispecific antibody, or chimeric ...
Ohmoto A, Fuji S, Shultes KC, Savani BN, Einsele H.   +4 more
europepmc   +3 more sources

Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]

, 2014
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
Matthew Buckland (589995), Lorena Lorenzo (589997), Matthew Buckland, Dempster, J, Duraisingham Sai S., Longhurst Hilary J., Matthew Buckl, Sai S. Duraisingham, Sofia Grigoriadou (589998), Sai S Duraisingham, Hilary J Longhurst, John Dempster, Dempster John, Grigoriadou Sofia, Duraisingham, SS, Lorenzo, L, Buckland Matthew, Grigoriadou, S, Sofia Grigoriadou, Lorenzo Lorena, Sai S. Duraisingham (589994), Buckland, M, Longhurst, HJ, Lorena Lorenzo, John Dempster (589996), Buckland, MS, Hilary J. Longhurst (589999), Hilary J. Longhurst   +27 more
core   +2 more sources

V_H replacement in rearranged immunoglobulin genes [PDF]

, 2005
Examples suggesting that all or part of the V_H segment of a rearranged V_HDJ_H may be replaced by all or part of another V_H have been appearing since the 1980s ...
Darlow, J.M., John M. Darlow, David I. Stott, Stott, D.I.   +3 more
core   +1 more source

Human inmmunoglobulin in primary immunodeficiencies

Acta Pediátrica de México, 2014
Human immunoglobulin replacement therapy has become a corner- stone in the treatment of patients with primary immunodeficiencies (PID). Currently indicated as first-line therapy for predominantly antibody deficiencies, severe combined immunodeficiencies,
Sheffler Mendoza Selma, Partida Gaytán Armando, Yamazaki Nakashimada Marco Antonio   +2 more
doaj   +1 more source

Immunoglobulin replacement therapy for yellow nail syndrome [PDF]

Scandinavian Journal of Immunology, 2018
Immunoglobulin replacement therapy for yellow nail ...
Lo Conte, C., ALLEGRINI, CHIARA, Matucci, A., Bartolucci, M., ROSI, ELIA, Camiciottoli, G., Amendola, M., Pistolesi, M., Bargagli, E.   +8 more
openaire   +5 more sources

Vaccination should not be forgotten in patients receiving immunoglobulin replacement therapy. [PDF]

Blood Adv
Einarsdottir S, Escribano-Serrat S, Gomez-Llobell M, Hultcrantz M, Kamboj M, Perales MA, Shouval R, Shahid Z, Ljungman P.   +8 more
europepmc   +3 more sources

Gene conversion in human rearranged immunoglobulin genes [PDF]

, 2006
Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V_H segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these
Darlow, J.M., John M. Darlow, David I. Stott, Stott, D.I.   +3 more
core   +1 more source

Intravenous Immunoglobulins: Mechanism of Action and Limitations of Clinical Application in Pediatrics

Zdorovʹe Rebenka, 2016
This review deals with an analysis of the available clinical studies and reports concerning the evaluation of the effectiveness and safety of intravenous immunoglobulins (IVIG) in various diseases in children. Intravenous immunoglobulins are drugs with a
S.O. Mokiia-Serbina
doaj   +1 more source

Subcutaneous immunoglobulin in lymphoproliferative disorders and rituximab-related secondary hypogammaglobulinemia: a single-center experience in 61 patients

Haematologica, 2014
Intravenous immunoglobulin replacement therapy represents the standard treatment for hypogammaglobulinemia secondary to B-cell lymphoproliferative disorders. Subcutaneous immunoglobulin infusion is an effective, safe and well-tolerated treatment approach
Nicolò Compagno, Francesco Cinetto, Gianpietro Semenzato, Carlo Agostini   +3 more
doaj   +1 more source