Immunoglobulin replacement therapies in inborn errors of immunity: a review
Immunoglobulins (Ig) were used as a therapeutic modality for the first time in a patient with X-linked agammaglobulinemia in 1952 by Colonel Ogden Bruton, decades before the molecular mechanisms causing the disease were unraveled.
Archan Sil +7 more
doaj +3 more sources
Managing Primary Immunodeficiency Immunoglobulin Replacement Therapy-Related Adverse Events With Recombinant Human C1 Esterase Inhibitor Prophylaxis: A Case Report. [PDF]
Immunoglobulin replacement therapy (IRT) for primary immunodeficiency reduces infection risk and subsequent complications and can be lifesaving. However, IRT can cause severe systemic adverse events (AEs) that may limit adequate dosing.
Jones DH, Memmott H.
europepmc +2 more sources
Immunoglobulin Replacement Therapy for Hypogammaglobulinemia in Multiple Myeloma Should Not Be Ignored [PDF]
Zhang Q, Wang Y, Pan W.
europepmc +2 more sources
Chronic lymphocytic leukaemia (CLL) is a malignancy of clonally expanded antigen-switched, neoplastic, mature B cells. CLL is characterised by a variable degree of immunosuppression and secondary hypogammaglobulinemia.
Sujoy Khan +3 more
doaj +1 more source
Immunoglobulin Replacement Therapy in Children [PDF]
The benefit of immunoglobulin (IG) replacement in primary antibody deficiencies is unquestionable. Many of these congenital disorders present early in life and this therapy is often first implemented in the young. This article focuses on the indications of IG replacement in children, with an emphasis on the specific diagnostic problems encountered in ...
Maria, Garcia-Lloret +2 more
openaire +2 more sources
Objective: In a large group of patients with primary immunodeficiency (PID), immunoglobulin replacement therapy is critical for infection control. There are two main methods of immunoglobulin replacement intravenous (IVIG) and subcutaneous (SCIG).
Selime Özen Bölük +9 more
doaj +1 more source
Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha +55 more
core +9 more sources
Treatment of patients with immunodeficiency: Medication, gene therapy, and transplantation
Objectives: To provide an overview of drug treatment, transplantation, and gene therapy for patients with primary immunodeficiencies. Source of data: Non-systematic review of the literature in the English language carried out at PubMed. Synthesis of data:
Gesmar Rodrigues Silva Segundo +1 more
doaj +1 more source
Health-Related Quality of Life in Patients with CVID Under Different Schedules of Immunoglobulin Administration: Prospective Multicenter Study [PDF]
We assessed the health-related quality of life (HRQoL) in CVID adults receiving different schedules of immunoglobulin replacement therapy (IgRT) by intravenous (IVIG), subcutaneous (SCIG), and facilitated (fSCIG) preparations.
Agostini, Carlo +13 more
core +2 more sources
Immunoglobulin replacement therapy for yellow nail syndrome [PDF]
Immunoglobulin replacement therapy for yellow nail ...
Lo Conte, C. +8 more
openaire +5 more sources

