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Immunoglobulin Replacement Therapy for Primary Immunodeficiencies
Immunotherapy, 2014 Exogenous antibody therapy to protect patients against infections and toxins is over 100 years old, yet progress continues to be made in the manufacture, administration and application of this type of immunotherapy, known as therapeutic human immunoglobulin. For the majority of patients with primary immunodeficiencies, immunoglobulin replacement is the
Helen Chapel
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Immunoglobulin Replacement Therapy in Children [PDF]
Immunology and Allergy Clinics of North America, 2008 The benefit of immunoglobulin (IG) replacement in primary antibody deficiencies is unquestionable. Many of these congenital disorders present early in life and this therapy is often first implemented in the young. This article focuses on the indications of IG replacement in children, with an emphasis on the specific diagnostic problems encountered in ...
Talal Chatila +2 more
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Immunoglobulin Replacement Therapy for Primary Immunodeficiency
Immunology and Allergy Clinics of North America, 2015Immunoglobulin replacement therapy has been standard treatment in patients with primary immunodeficiency diseases for the past 3 decades. The goal of therapy is to reduce serious bacterial infections in individuals with antibody function defects. Approximately one-third of patients receiving intravenous immunoglobulin treatment experience adverse ...
Panida Sriaroon, Mark Ballow
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International Immunopharmacology, 2017 Immunoglobulin therapy is the administration of human polyvalent IgG and represents the most effective treatment to prevent recurrent infections in antibody deficiency patients. Primary antibody deficiency represents the main indication of immunoglobulin
Giuseppe Spadaro +2 more
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Outcome of Immunoglobulin Replacement Therapy in Adults With Rhinosinusitis
The Laryngoscope, 2021ObjectiveTo evaluate the outcome of immunoglobulin (IG) replacement therapy in adults with rhinosinusitis and primary humoral immunodeficiency disorders (PID).Study DesignRetrospective cohort study.MethodsRetrospective chart review of adult (18 years and older) patients who were diagnosed with PID and had the diagnosis of recurrent acute rhinosinusitis
Chadi A. Makary +3 more
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Aspects of immunoglobulin replacement therapy
The Pediatric Infectious Disease Journal, 1990Immunoglobulin replacement therapy appears to benefit some patients who have IgG subclass deficiencies. Because some patients with subnormal trough concentrations of IgG subclasses remain well, because other patients who have borderline/low normal concentrations of an IgG subclass are abnormally infection-prone and helped by immunoglobulin therapy and ...
L J, Beard, A, Ferrante
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Subcutaneous Immunoglobulin Replacement Therapy
Journal of Infusion Nursing, 2015Subcutaneous immunoglobulin (SCIg) infusions are an option for patients requiring immunoglobulin therapy. Nurses are uniquely positioned to advocate for patients and to teach them how to successfully manage their infusions. The purpose of this review is to describe SCIg therapy and to provide teaching instructions as well as creative tips to ensure ...
M Elizabeth M, Younger +5 more
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Immunoglobulin Replacement Therapy by Slow Subcutaneous Infusion
Annals of Internal Medicine, 1980Excerpt Alcohol fractionated immune serum globulin and fresh frozen plasma are the only generally available preparations used for replacement therapy in patients with antibody deficiency syndromes....
M, Berger, T R, Cupps, A S, Fauci
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Nursing Guidelines for Administration of Immunoglobulin Replacement Therapy
Journal of Infusion Nursing, 2013Immunoglobulin (Ig) replacement therapy, given as regular infusions of pooled human Ig, is the recognized treatment of humoral immunodeficiencies characterized by hypogammaglobulinemia and impaired antibody responses. It is a safe, effective therapy when delivered by nurses who have been educated to oversee and/or provide these infusions.
Mary Elizabeth M, Younger +6 more
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Immunoglobulin Replacement Therapy
1988The basic concept that specific plasma substances can be important in host defence is a central theme in the historical development of immunology. As early as 1890, von Behring and Kitasato discovered that neutralizing antisera to tetanus and diphtheria toxins could be produced in animals by prior exposure to antigen and that the active principle was ...
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