Results 71 to 80 of about 70,538 (300)

ICAM G241A polymorphism and soluble ICAM-1 serum levels: Evidence for an active immune process in schizophrenia [PDF]

, 2005
Objectives: We have previously reported reduced serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) in schizophrenic patients. A single-nucleotide polymorphism ( SNP) of the ICAM-1 gene was described at position 241.
Ackenheil, Manfred, Kronig, H., Möller, Hans-Jürgen, Müller, Norbert, Riedel, M., Schwarz, Markus J., Strassnig, M.   +6 more
core   +1 more source

Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease

Therapeutics and Clinical Risk Management, 2009
Suzanne Skoda-Smith, Troy R Torgerson, Hans D OchsSeattle Children’s Research Institute and Department of Pediatrics, University of Washington, Seattle, WashingtonAbstract: Antibody deficiency is the most frequently encountered primary ...
Suzanne Skoda-Smith, Troy R Torgerson, Hans D Ochs   +2 more
doaj  

Good? A very long COVID-19Chronic pulmonary SARS-CoV2 infection associated to Good syndrome [PDF]

Journal of Human Immunity
We report a case of chronic pulmonary SARS-CoV2 infection caused by impaired B cell–mediated immunity to SARS-CoV-2 in a patient with Good syndrome. Immunoglobulin replacement therapy alone was sufficient to achieve clinical and radiological resolution.
Quentin Philippot, Marie-Pierre Debray, Alice Guyard, Antoine Achkar, Tom Le Voyer, Quentin Le Hingrat, Bruno Crestani, Raphaël Borie   +7 more
doaj   +1 more source

Bronchiectasis and deteriorating lung function in agammaglobulinaemia despite immunoglobulin replacement therapy [PDF]

Clinical and Experimental Immunology, 2017
SummaryImmunoglobulin replacement therapy enhances survival and reduces infection risk in patients with agammaglobulinaemia. We hypothesized that despite regular immunoglobulin therapy, some patients will experience ongoing respiratory infections and develop progressive bronchiectasis with deteriorating lung function.
A Stubbs, C Bangs, B Shillitoe, J D Edgar, S O Burns, M Thomas, H Alachkar, M Buckland, E McDermott, G Arumugakani, M S Jolles, R Herriot, P D Arkwright   +12 more
openaire   +6 more sources

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Clinical and laboratory parameter analysis in patients with common Variable Immunodeficiency [PDF]

Medicinski Podmladak, 2022
Introduction: Common Variable Immunodeficiency (CVID) is the most prevalent primary immunodeficiency in adult population. The diagnosis is based on low concentration of at least 2 immunoglobulin classes, mostly IgG, with low IgA and/or IgM.
Krtinić Danka, Stojanović Maja
doaj  

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Housing, management and health in Swedish dairy calves [PDF]

, 2004
This thesis discusses the results of an observational study conducted in dairy herds in the south-western Sweden and a questionnaire survey of dairy herds done throughout Sweden.
Lundborg, Karin
core  

Early-onset primary antibody deficiency resembling common variable immunodeficiency challenges the diagnosis of Wiedeman-Steiner and Roifman syndromes [PDF]

, 2017
Syndromic primary immunodeficiencies are rare genetic disorders that affect both the immune system and other organ systems. More often, the immune defect is not the major clinical problem and is sometimes only recognized after a diagnosis has been made ...
Bogaert, Delfien, Coppieters, Frauke, De Baere, Elfride, De Baets, Frans, De Bruyne, Marieke, De Schryver, Sarah, De Wilde, Hans, Dullaers, Melissa, Haerynck, Filomeen, Kuehn, Hye Sun, Lambrecht, Bart, Leroy, Bart, Niemela, Julie E, Rosenzweig, Sergio D   +13 more
core   +2 more sources

Rituximab-associated Hypogammaglobulinemia in pediatric patients with autoimmune diseases

Pediatric Rheumatology Online Journal, 2019
Background Despite the increased use of rituximab in treating pediatric patients with autoimmune diseases in the last decade, there are limited data on rituximab safety in those subjects who have a developing immune system. The objective of this study is
Amer M. Khojah, Michael L. Miller, Marisa S. Klein-Gitelman, Megan L. Curran, Victoria Hans, Lauren M. Pachman, Ramsay L. Fuleihan   +6 more
doaj   +1 more source