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Fish Immunoglobulins [PDF]

open access: yesBiology, 2016
The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In this review, we summarize what is known of the immunoglobulin genes of jawed cartilaginous and bony fishes. We focus on what has been learned from genomic or cDNA
Sara Mashoof, Michael F. Criscitiello
doaj   +4 more sources

Immunoglobulins, Mucosal Immunity and Vaccination in Teleost Fish

open access: yesFrontiers in Immunology, 2020
Due to direct contact with aquatic environment, mucosal surfaces of teleost fish are continuously exposed to a vast number of pathogens and also inhabited by high densities of commensal microbiota.
Yongyao Yu   +6 more
doaj   +2 more sources

Prednisolone associated with doxycycline on the hematological parameters and serum proteinogram of dogs with ehrlichiosis [PDF]

open access: yesCiência Rural, 2021
: The objective of the present study was to assess the treatment of dogs with ehrlichiosis (tropical canine pancytopenia (TCP)) with doxycycline hydrochloride associated or not with prednisolone on the hematological profile and serum proteins.
Ariana de Castro Tavares da Silva   +9 more
doaj   +1 more source

Association of Intravenous Immunoglobulins Plus Methylprednisolone vs Immunoglobulins Alone With Course of Fever in Multisystem Inflammatory Syndrome in Children.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Multisystem inflammatory syndrome in children (MIS-C) is the most severe pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection, potentially life-threatening, but the optimal therapeutic strategy remains ...
N. Ouldali   +31 more
semanticscholar   +1 more source

Immunoglobulin Classification Based on FC* and GC* Features

open access: yesFrontiers in Genetics, 2022
Immunoglobulins have a pivotal role in disease regulation. Therefore, it is vital to accurately identify immunoglobulins to develop new drugs and research related diseases. Compared with utilizing high-dimension features to identify immunoglobulins, this
Hao Wan   +4 more
doaj   +1 more source

Potential of Chlorella sp. exopolysaccharide as adjuvant for Mannheimia haemolytica A2 vaccine in rat model [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2021
The potential of exopolysaccharides (EPS) extracted from Chlorella sp. as adjuvant for formalin-killed whole organism of Mannheimia haemolytica A2 (MhA2) vaccine was investigated. Chlorella sp.
Insyirah-husna Kamaradin   +3 more
doaj   +1 more source

Repression of the stress granule protein G3BP2 inhibits immune checkpoint molecule PD‐L1

open access: yesMolecular Oncology, EarlyView., 2022
Mounting evidence suggests that cancer stemness and immunosuppression are related, but the underlying mechanisms are not clear. We previously reported that the stress granule‐associated protein G3BP2 is involved in regulating tumor‐initiating (stem) cells.
Yanhong Zhang   +3 more
wiley   +1 more source

V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation

open access: yesImmunology, 2020
Immunoglobulins emerging from B lymphocytes and capable of recognizing almost all kinds of antigens owing to the extreme diversity of their antigen‐binding portions, known as variable (V) regions, play an important role in immune responses.
Xiying Chi, Yue Li, Xiaoyan Qiu
semanticscholar   +1 more source

Immunoglobulins and immunoglobulin subclasses in the elderly [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2003
Background: Published data imply that adult concentrations are achieved for all Ig isotypes and plateau by 15--18 years of age. Recent data, however, suggest that these results are not applicable in the elderly. There are no equivalent data for IgG subclasses.
Robert J Lock, David J Unsworth
openaire   +3 more sources

Autoimmunity in Pulmonary Arterial Hypertension: Evidence for Local Immunoglobulin Production

open access: yesFrontiers in Cardiovascular Medicine, 2021
Pulmonary arterial hypertension (PAH) is a progressive life-threatening disease. The notion that autoimmunity is associated with PAH is widely recognized by the observations that patients with connective tissue diseases or virus infections are more ...
Ting Shu, Yanjiang Xing, Jing Wang
doaj   +1 more source

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