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Biology, 2016 The B cell receptor and secreted antibody are at the nexus of humoral adaptive immunity. In this review, we summarize what is known of the immunoglobulin genes of jawed cartilaginous and bony fishes. We focus on what has been learned from genomic or cDNA
Sara Mashoof, Michael F. Criscitiello
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Immunoglobulins, Mucosal Immunity and Vaccination in Teleost Fish
Frontiers in Immunology, 2020 Due to direct contact with aquatic environment, mucosal surfaces of teleost fish are continuously exposed to a vast number of pathogens and also inhabited by high densities of commensal microbiota.
Yongyao Yu +6 more
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An Atypical Immunoglobulin [PDF]
Blood, 1968 Abstract A protein of the Ig G family has been isolated from the serum of a patient with a tentative diagnosis of a plasma cell neoplasm. The protein has a lower sedimentation constant (5.4) and a lower molecular weight (125,000) than normal immunoglobulins of the G family.
Alison Lewis +4 more
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Prednisolone associated with doxycycline on the hematological parameters and serum proteinogram of dogs with ehrlichiosis [PDF]
Ciência Rural, 2021 : The objective of the present study was to assess the treatment of dogs with ehrlichiosis (tropical canine pancytopenia (TCP)) with doxycycline hydrochloride associated or not with prednisolone on the hematological profile and serum proteins.
Ariana de Castro Tavares da Silva +9 more
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Journal of the American Medical Association (JAMA), 2021 Importance Multisystem inflammatory syndrome in children (MIS-C) is the most severe pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection, potentially life-threatening, but the optimal therapeutic strategy remains ...
N. Ouldali +31 more
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Immunoglobulin Classification Based on FC* and GC* Features
Frontiers in Genetics, 2022 Immunoglobulins have a pivotal role in disease regulation. Therefore, it is vital to accurately identify immunoglobulins to develop new drugs and research related diseases. Compared with utilizing high-dimension features to identify immunoglobulins, this
Hao Wan +4 more
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Immunology, 2020 Immunoglobulins emerging from B lymphocytes and capable of recognizing almost all kinds of antigens owing to the extreme diversity of their antigen‐binding portions, known as variable (V) regions, play an important role in immune responses.
Xiying Chi, Yue Li, Xiaoyan Qiu
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Serum differential proteomic profiling of patients with isolated methylmalonic acidemia by iTRAQ
Frontiers in Genetics, 2022 Isolated methylmalonic acidemia (MMA) is an inherited organic acid metabolic disorder in an autosomal recessive manner, caused by mutations in the methylmalonyl coenzyme A mutase gene, and the isolated MMA patients often suffer from multi-organ damage ...
Sitao Li +9 more
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Detection of SARS-CoV-2 Specific Antibodies in Saliva Samples
Frontiers in Immunology, 2022 Molecular assays on nasopharyngeal swabs act as a confirmatory test in coronavirus disease (COVID-19) diagnosis. However, the technical requirements of nasopharyngeal sampling and molecular assays limit the testing capabilities.
Siyang Yu +13 more
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Immunoglobulins and immunoglobulin subclasses in the elderly [PDF]
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2003 Background: Published data imply that adult concentrations are achieved for all Ig isotypes and plateau by 15--18 years of age. Recent data, however, suggest that these results are not applicable in the elderly. There are no equivalent data for IgG subclasses.
Robert J Lock, David J Unsworth
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