Results 11 to 20 of about 182,946 (270)
Learning the statistics and landscape of somatic mutation-induced insertions and deletions in antibodies [PDF]
, 2021 Affinity maturation is crucial for improving the binding affinity of antibodies to antigens. This process is mainly driven by point substitutions caused by somatic hypermutations of the immunoglobulin gene. It also includes deletions and insertions of genomic material known as indels.
arxiv +1 more source
Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022 Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao +8 more
wiley +1 more source
Haematologica, 2010 Background Type G immunoglobulins against ADAMTS13 are the primary cause of acquired (idiopathic) thrombotic thrombocytopenic purpura. However, the domains of ADAMTS13 which the type G anti-ADAMT13 immunoglobulins target have not been investigated in a ...
X. Long Zheng +7 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 The study was aimed to examine the effects of age and dietary beta-hydroxybutyric acid (BHBA) on blood BHBA and blood health indicators in goat kids.
Mahmoud M. Abdelsattar +5 more
doaj +1 more source
Method for identification of condition-associated public antigen receptor sequences [PDF]
eLife 2018;7:e33050, 2017 Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire sequencing methods makes it possible to perform repertoire-wide disease association studies of antigen receptor sequences.
arxiv +1 more source
Current treatment in COVID-19 disease: a rapid review
Drugs in Context, 2021 The world has faced the most challenging pandemic of the modern era, that of severe acute respiratory syndrome coronavirus 2 infection, causing coronavirus disease and affecting over 35 million people globally.
Miguel Rodriguez-Guerra +2 more
doaj +1 more source
Immunoglobulins in neurological practice: a review of the literature
Нервно-мышечные болезни, 2019 Today intravenous immunoglobulins are used increasingly in the management of patients with neurological conditions. The efficacy and safety of intravenous immunoglobulins treatment in chronic inflammatory demyelinating polyradiculoneuropathy, Guillain ...
S. S. Nikitin, L. M. Boriskina
doaj +1 more source
The role of small intestine in pathogenesis of common variable immune deficiency [PDF]
Терапевтический архив, 2018 The article presents the results of examination of 32 patients with common variable immune deficiency (barn) with involvement in the pathological process of the digestive system. The features of the clinical picture, the content of immunoglobulins in the
L M Krums +4 more
doaj +1 more source
Role of Immunoglobulins in Muscular Dystrophies and Inflammatory Myopathies
Frontiers in Immunology, 2021 Muscular dystrophies and inflammatory myopathies are heterogeneous muscular disorders characterized by progressive muscle weakness and mass loss. Despite the high variability of etiology, inflammation and involvement of both innate and adaptive immune ...
Andrea Farini +4 more
doaj +1 more source
Immunomodulatory and Prebiotic Effects of 2′-Fucosyllactose in Suckling Rats
Frontiers in Immunology, 2019 Human milk oligosaccharides are unconjugated complex glycans present in high concentration in human milk that serve as pre-biotics and immunomodulators.
Ignasi Azagra-Boronat +20 more
doaj +1 more source