Results 91 to 100 of about 1,221,475 (381)

Comparison of the solophenyl-red polarization method and the immunohistochemical analysis for collagen type III [PDF]

, 1992
In the present study, we have compared the staining pattern of the Solophenyl-Red 3 BL-method for the visualization of collagen type III with the immunohistochemical staining in serial sections from 7 skin wounds (wound age 3 days up to 4 weeks) to ...
A Nerlich, A Nerlich, A. Nerlich, AJ D'Ardenne, DJ Unsworth, EJ Macarak, GE Piérard, I. Wiest, J. Wilske, K Mark von der, LCU Junqueira, LCU Junqueira, LCU Junqueira, P. Betz, R Timpl, R. Penning, RH Kramer, S Ogbuihi, S Stenman, SM Hsu, SRP Line, W Eisenmenger, W. Eiseumenger   +22 more
core   +1 more source

Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry

Journal of Clinical Pathology, 2016
Increased expression levels of KCNJ3 have been correlated with lymph node metastases and poor prognosis in patients with breast cancer, suggesting a prognostic role of KCNJ3.
Y. Ju, L. Alexandrov, M. Gerstung, I. Martincorena, S. Nik-Zainal, Manasa Ramakrishna, Helen R Davies, E. Papaemmanuil, G. Gundem, A. Shlien, N. Bolli, S. Behjati, P. Tarpey, J. Nangalia, C. Massie, Adam P. Butler, J. Teague, G. Vassiliou, A. Green, Mingyuan Du, Ashwin Unnikrishnan, J. Pimanda, B. Teh, N. Munshi, M. Greaves, P. Vyas, A. E. Naggar, T. Santarius, V. P. Collins, Richard Grundy, Jack A. Taylor, D. Hayes, D. Malkin, Christopher S. Foster, A. Warren, H. Whitaker, D. Brewer, R. Eeles, Colin S. Cooper, D. E. Neal, T. Visakorpi, W. Isaacs, G. Bova, A. Flanagan, P. Futreal, A. Lynch, P. Chinnery, Ultan McDermott, Michael R. Stratton, Peter J. Campbell   +49 more
semanticscholar   +1 more source

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

Molecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits, Barbara Andrea Reinoehl, Renate Wagner, Peter Kuess, Franziska Eckert, Anna Sophie Berghoff, Thorsten Fuereder, Rotraud Wieser   +7 more
wiley   +1 more source

Immunohistochemistry guided segmentation of benign epithelial cells, in situ lesions, and invasive epithelial cells in breast cancer slides [PDF]

arXiv, 2023
Digital pathology enables automatic analysis of histopathological sections using artificial intelligence (AI). Automatic evaluation could improve diagnostic efficiency and help find associations between morphological features and clinical outcome. For development of such prediction models, identifying invasive epithelial cells, and separating these ...
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B., Chrousos, G. P., Karl, M., Linehan, M., Mastorakis, G., Reincke, Martin, Travis, W.   +6 more
core  

The Intratumoral Heterogeneity Reflects the Intertumoral Subtypes of Glioblastoma Multiforme: A Regional Immunohistochemistry Analysis

Frontiers in Oncology, 2020
Glioblastoma multiforme (GBM) is the most frequent and aggressive primary brain tumor in adults. Despite extensive therapy the prognosis for GBM patients remains poor and the extraordinary therapy resistance has been attributed to intertumoral ...
Natalie Bergmann, C. Delbridge, J. Gempt, A. Feuchtinger, A. Walch, Lucas Schirmer, W. Bunk, T. Aschenbrenner, F. Liesche-Starnecker, J. Schlegel   +9 more
semanticscholar   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

Molecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch, Sara Sánchez‐Serra, Marta Rosàs‐Lapeña, Nicolás Costa‐Fraga, Judit Besalú‐Velázquez, Janet Illa‐Bernadí, Silvia Mateo‐Lozano, Florencia Cidre‐Aranaz, Thomas G.P. Grünewald, Ángel Díaz‐Lagares, Roser Lopez‐Alemany, Òscar M. Tirado   +11 more
wiley   +1 more source

The effect of low doses of cadmium and zinc chloride on the Blood-Testis Barrier of Sprague Dawley rats [PDF]

arXiv, 2012
Background: Cadmium chloride is an environmental toxic that affects the male reproductive system. This study was directed 1) to evaluate whether long-term oral exposures to low doses of Cd in rats causes morphological changes, 2) the immunohistochemical TJ and AJ protein expression; and 3) to evidence that zinc exposure can modify Cd effects.
arxiv  

The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions. [PDF]

, 2017
The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection
Angelini, A, Berry, GJ, Bruneval, P, Dragun, D, Duong Van Huyen, JP, Fedrigo, M, Haas, M, Loupy, A, Mengel, M, Miller, D, Potena, L, Reed, EF, Reinsmoen, N, Revelo, P, Smith, RN, Tebutt, S, Thum, T, West, L, Zeevi, A   +18 more
core   +1 more source