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Immunohistochemistry (IHC) or immunocytochemistry is a method of localizing specific antigen in tissue or cells based on antigen antibody reaction. IHC is the way of validating morphological findings.
G Aryal
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Applications of immunohistochemistry
Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease.
Jeyapradha Duraiyan +3 more
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Immunohistochemistry: Relevance in dermatology
Use of immunohistochemical technique is increasing in diagnosing various diseases. In many situations it may not be possible to differentiate entities with overlapping clinical and histopathological features.
Aparna Palit, Arun C Inamadar
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Immunohistochemistry allows specific proteins to be visualized while retaining cellular or tissue structure. Sensitivity of the technique has improved over the years from a single layer of labeled antibody to amplified, labeled polymer-based systems, which enable low levels of antigen to be detected in different types of tissue preparation.
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Background Oral squamous cell carcinoma (OSCC) is the most relevant malignant neoplasm among all head and neck tumours due to its high prevalence and unfavourable prognosis.
Geovanni Pereira Mitre +5 more
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HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
Background. Ameloblastoma (AMB) is a benign odontogenic tumour, with an aggressive local behaviour and a high rate of recurrence. Previous studies have demonstrated that hypoxia-induced factor alpha 1 (HIF-1α) and activated caspase-3 contribute to tumour
Katherine Julissa Palma Valladares +10 more
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Runt-related transcription factor 2 (Runx2) measurement in phytoestrogen-induced bone: a comparison of western blot and immunohistochemistry methods [PDF]
Estrogen deficiency can contribute to osteoporosis in postmenopausal women. Phytoestrogens are becoming more widely recognized as potential estrogen replacement therapy. The administration of phytoestrogens can cause bone formation, which is marked by an
Ma'arif, Burhan +5 more
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Expression of stem cell markers SALL4, LIN28A, and KLF4 in ameloblastoma
Background Ameloblastoma (AME) is a benign odontogenic tumour of epithelial origin characterised by slow but aggressive growth, infiltration, and recurrence; it is capable of reaching large dimensions and invading adjacent structures.
Rafaela de Albuquerque Dias +4 more
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This study was aimed at analyzing the relations of metastasis to regional lymph nodes (RLNs) with histopathological indicators of invasive breast carcinoma of no special type (IC-NST) and its cytokine profile.
Alexander Autenshlyus +7 more
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Basics of Immunohistochemistry [PDF]
INTRODUCTION Immunohistochemistry (IHC) is a powerful method for localizing specific antigens in formalin-fixed, paraffin-embedded (FFPE) tissues based on antigen–antibody interaction (Taylor and Burns, 1974). The technique is widely used in dermatologic diagnostics and research, and its applications continue to be extended because of its ease of use ...
Schacht, Vivien, Kern, Johannes S.
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