Results 21 to 30 of about 996,507 (292)

Aging Induces Changes in the Somatic Nerve and Postsynaptic Component without Any Alterations in Skeletal Muscles Morphology and Capacity to Carry Load of Wistar Rats

Frontiers in Neuroscience, 2017
The present study aimed to analyze the morphology of the peripheral nerve, postsynaptic compartment, skeletal muscles and weight-bearing capacity of Wistar rats at specific ages.
Walter Krause Neto, Wellington de Assis Silva, Adriano P. Ciena, Romeu R. de Souza, Carlos A. Anaruma, Eliane F. Gama   +5 more
doaj   +1 more source

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer

Frontiers in Oncology, 2021
Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within KRAS and BRAF genes.
Maria Dobre, Alessandro Salvi, Iulia Andreea Pelisenco, Florina Vasilescu, Giuseppina De Petro, Vlad Herlea, Elena Milanesi   +6 more
doaj   +1 more source

Testicular degeneration and infertility following arbovirus infection [PDF]

, 2018
Arboviruses can cause a variety of clinical signs including febrile illness, arthritis, encephalitis and hemorrhagic fever. The recent Zika epidemic highlighted the possibility that arboviruses may also negatively affect the male reproductive tract.
Dattena, Maria, Ligios, Ciriaco, Maestrale, Caterina, Manunta, Daniela, Meloni, Giorgio, Melzi, Eleonora, Oggiano, Annalisa, Palmarini, Massimo, Pintus, Davide, Puggioni, Giantonella, Rocchigiani, Angela Maria, Savini, Giovanni   +11 more
core   +1 more source

Therapeutic efficacy of plant-based hydrogels in burn wound healing: focus on Satureja montana L. and Origanum vulgare L [PDF]

Scripta Medica
Background/Aim: Burn injuries present a critical issue for healthcare systems worldwide. They often lead to numerous complications, including persistent inflammation, impaired healing and heightened infection risks.
Demyashkin Grigory A., Parshenkov Mikhail A., Tokov Alibek A., Sataieva Tatiana P., Shevkoplyas Ludmila A., Said Bekeev S., Shamil Gasanbekov N.   +6 more
doaj   +1 more source

Crocus sativus Extract as a Biological Agent for Disease-Modifying Therapy of Collagenase-Induced Mouse Model of Osteoarthritis

Life, 2023
Objectives: Osteoarthritis (OA) is an age-related joint disease that involves the degeneration of cartilage and is the most prevalent form of arthritis, affecting a large part of the population.
Blagovesta Boneva, Andrey Marchev, Kristiana Amirova, Petya Ganova, Milen Georgiev, Andrey Tchorbanov, Nikolina Mihaylova   +6 more
doaj   +1 more source

An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma [PDF]

, 2016
The conserved Myb-MuvB (MMB) multiprotein complex has an important role in transcriptional activation of mitotic genes. MMB target genes are overexpressed in several different cancer types and their elevated expression is associated with an advanced ...
Francke, S., Garcia, P., Gaubatz, S., Hauser, S., Iltzsche, F., Murphy, D.J., Pattschull, G., Rosenwald, A., Simon, K., Stopp, S., Wolter, P.   +10 more
core   +2 more sources

Effect Of Different Grip Position And Shoulder- Abduction Angle On Muscle Strength And Activation During The Seated Cable Row

International Journal of Strength and Conditioning, 2023
The purpose of this study was to compare the peak force and electromyographic activation in different techniques of the seated row. Eleven recreationally trained male (28±5 years, 176±5 cm, 94±16 kg) and ten female (27±5 years, 168±8 cm, 65±11 kg ...
Christine Megumi Wakuda de Abreu Vasconcelos, Charles Ricardo Lopes, Vinícius Martins Almeida, Walter Krause Neto, Enrico Soares   +4 more
doaj   +1 more source

JAK3 as an emerging target for topical treatment of inflammatory skin diseases [PDF]

, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Alves de Medeiros, Ana, De Schepper, Sofie, Desmet, Eline, Lambert, Jo, Speeckaert, Reinhart, Van Gele, Mireille   +5 more
core   +2 more sources

Effects of Strength Training and Anabolic Steroid in the Peripheral Nerve and Skeletal Muscle Morphology of Aged Rats

Frontiers in Aging Neuroscience, 2017
Thirty male 20-month-old Wistar rats were divided into groups: IC—initial control (n = 6), FC—final control (n = 6), AC—anabolic hormone control (n = 6), ST—strength trained (n = 6) and STA—strength trained with anabolic hormone (n = 6).
Walter Krause Neto, Wellington de A. Silva, Adriano P. Ciena, Ricardo Aparecido Baptista Nucci, Carlos A. Anaruma, Eliane F. Gama   +5 more
doaj   +1 more source

Muc5ac mucin expression during rat skin development [PDF]

, 2015
Some mucin genes have been detected during human embryonic and fetal organ development; however, little is known about mucin expression in epidermal development, neither in humans nor in other species. The present research was developed to explore Muc5ac
Barbeito, Claudio Gustavo, Croce, María Virginia, Ferretti, Valeria, Segal Eiras, Amada   +3 more
core   +2 more sources