Results 31 to 40 of about 853,198 (295)

Cytokeratin and Vimentin Expression in Breast Cancer

open access: yesThe International Journal of Biological Markers, 2009
Background The transition from epithelial keratin to mesenchymal vimentin expression marks an important step in the malignant progression of breast cancer.
Hemangini H. Vora   +7 more
doaj   +1 more source

Cytoplasmic Localization of BAG-1 in Leukoplakia and Carcinoma of the Tongue: Correlation with p53 and C-Erbb2 in Carcinoma

open access: yesThe International Journal of Biological Markers, 2007
Background The present study evaluated the clinical significance of BAG-1, an antiapoptotic protein, in leukoplakia and carcinoma of the tongue. Methods BAG-1 expression was evaluated by immunohistochemistry in paraffin-embedded tissues of leukoplakia (n=
H.H. Vora   +6 more
doaj   +1 more source

Pharmacological potential of Inonotus obliquus: An integrative review of antitumour, immunomodulatory and anti-inflammatory effects [PDF]

open access: yesScripta Medica
Inonotus obliquus (Chaga mushroom), long used in traditional medicine, has recently gained substantial scientific attention due to its diverse pharmacological activities. While numerous preclinical studies exist, the lack of a comprehensive understanding
Osipova Daniella   +6 more
doaj   +1 more source

Evaluation of metal contamination effects in piranhas through biomonitoring and multi biomarkers approach

open access: yesHeliyon, 2020
The present field study aimed to assess the water quality of the Itacaiúnas River, located at the eastern part of the Brazilian Amazon, using water's physicochemical parameters, ecological risk assessment in sediments, biomarkers and metal ...
Caroline da Silva Montes   +4 more
doaj   +1 more source

Automated Segmentation of Cells with IHC Membrane Staining [PDF]

open access: yes, 2011
This study presents a fully automated membrane segmentation technique for immunohistochemical tissue images with membrane staining, which is a critical task in computerized immunohistochemistry (IHC).
A Acquaviva   +7 more
core   +1 more source

Aging Induces Changes in the Somatic Nerve and Postsynaptic Component without Any Alterations in Skeletal Muscles Morphology and Capacity to Carry Load of Wistar Rats

open access: yesFrontiers in Neuroscience, 2017
The present study aimed to analyze the morphology of the peripheral nerve, postsynaptic compartment, skeletal muscles and weight-bearing capacity of Wistar rats at specific ages.
Walter Krause Neto   +5 more
doaj   +1 more source

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer

open access: yesFrontiers in Oncology, 2021
Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within KRAS and BRAF genes.
Maria Dobre   +6 more
doaj   +1 more source

Issues in Immunohistochemistry [PDF]

open access: yesToxicologic Pathology, 1999
Immunohistochemistry is a powerful technique used to localize specific molecules in tissues. Literally thousands of immunoreagents specific for an incredibly diverse number of molecules are commercially available, and some of these immunoreagents will detect minute quantities of target molecule in tissues.
openaire   +2 more sources

Therapeutic efficacy of plant-based hydrogels in burn wound healing: focus on Satureja montana L. and Origanum vulgare L [PDF]

open access: yesScripta Medica
Background/Aim: Burn injuries present a critical issue for healthcare systems worldwide. They often lead to numerous complications, including persistent inflammation, impaired healing and heightened infection risks.
Demyashkin Grigory A.   +6 more
doaj   +1 more source

Crocus sativus Extract as a Biological Agent for Disease-Modifying Therapy of Collagenase-Induced Mouse Model of Osteoarthritis

open access: yesLife, 2023
Objectives: Osteoarthritis (OA) is an age-related joint disease that involves the degeneration of cartilage and is the most prevalent form of arthritis, affecting a large part of the population.
Blagovesta Boneva   +6 more
doaj   +1 more source

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