Results 111 to 120 of about 2,266 (210)

Leveraging immunoinformatic techniques for the development of a multi-epitope subunit vaccine targeting virulence-associated proteins of Mycobacterium tuberculosis

open access: yes
Among infectious diseases, tuberculosis is the biggest cause of death worldwide. Thus, controlling TB, a global epidemic, is a major public health concern on a worldwide scale. According to epidemiological modelling, a new vaccination that can prevent TB,
Salah-Ud-Din Khan   +8 more
core   +1 more source

Antigenic Protein Screening and Design of Multi‐Epitope Vaccine Against Lactococcus garvieri and Streptococcus iniae for Combating Lactococcosis and Streptococcosis in Fish

open access: yesVeterinary Medicine and Science
The illness caused by Lactococcus garvieae and Streptococcus iniae is well acknowledged as a disease that results in significant economic losses since it affects a diverse array of fish species.
Ramesh Ranjbar   +2 more
doaj   +1 more source

Novel Reoviruses of Waterfowl Origin in Northern Vietnam: A Laboratory Investigation

open access: yesMicrobiology Research
Novel waterfowl reoviruses (nWRVs) have been reported in several countries, but their circulation and genetic characteristics in Vietnam remain poorly understood. In this study, we investigated nWRVs in northern Vietnam through molecular detection, virus
Thi-Ngoc Vu   +4 more
doaj   +1 more source

Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori.

open access: yes
Helicobacter pylori is a gram-negative bacterium that persistently infects the human stomach, leading to peptic ulcers, gastritis, and an increased risk of gastric cancer.
Imren Bayil   +11 more
core   +1 more source

Immunoinformatic approach to the design of a novel multi-epitope vaccine against Leishmania major fused to human IgG-Fc

open access: yes
Background and purpose: Cutaneous leishmaniasis poses significant health and socioeconomic challenges, making vaccine development a top priority, especially in endemic regions.
Mahmood Fadaie   +2 more
core   +1 more source

In Silico Analysis and Optimization of Multi-Epitope mRNA Vaccine Candidates Derived from the Proteome of Toxocara canis [PDF]

open access: yesJournal of Basic Research in Medical Sciences
Introduction: Toxocara canis is a significant zoonotic parasite that remains inadequately controlled. This study utilized a range of immunoinformatics methodologies to develop a candidate multi-epitope mRNA vaccine against T. canis.
Roohollah Fattahi
doaj  

Designing of potential vaccine candidates of fused cathepsin L and tropomyosin genes of Rhipicephalus (Boophilus) annulatus tick larva

open access: yesJournal of Basic Research in Medical Sciences, 2018
Introduction: Regarding emerging tick resistance against acaricides, researches have been shifted toward alternative approaches such as immunologic methods.
Zahra Asadollahi   +4 more
doaj  

Identification of Schistosoma haematobium and Schistosoma mansoni linear B-cell epitopes with diagnostic potential using in silico immunoinformatic tools and peptide microarray technology

open access: yes
Immunoinformatic tools can be used to predict schistosome-specific B-cell epitopes with little sequence identity to human proteins and antigens other than the target.
Mduluza, Takafira   +7 more
core   +3 more sources

Immunoinformatic design of chimeric multiepitope vaccine for the prevention of human metapneumovirus (hMPV)

open access: yes
Background Human metapneumovirus (hMPV) is a significant etiological agent of acute respiratory infections in children and immunocompromised individuals.
Mohammad Salavatizadeh   +2 more
core   +1 more source

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