Results 51 to 60 of about 8,611 (248)

FRED 2: an immunoinformatics framework for Python [PDF]

Bioinformatics, 2016
Abstract Summary: Immunoinformatics approaches are widely used in a variety of applications from basic immunological to applied biomedical research. Complex data integration is inevitable in immunological research and usually requires comprehensive pipelines including multiple tools and data sources. Non-standard input and output formats
Schubert, Benjamin, Walzer, Mathias, Brachvogel, Hans-Philipp, Szolek, András, Mohr, Christopher, Kohlbacher, Oliver   +5 more
openaire   +3 more sources

The effects of cryopreservation on PBMCs transcriptome profile

Frontiers in Immunology
Cryopreservation is a key method for long-term storage of biological specimens. The development of optimal cryopreservation and recovery conditions will minimize storage-related damage. The effect of the cryopreservation and recovery condition we used on
Xuan Li, Qian Chen, Jeanette Higgins, Kyndal Cook, Michael W. Baseler, Tomozumi Imamichi, Weizhong Chang   +6 more
doaj   +1 more source

Epitopedia: identifying molecular mimicry between pathogens and known immune epitopes

ImmunoInformatics, 2023
Upon infection, foreign antigenic proteins stimulate the host's immune system to produce antibodies targeting the pathogen. These antibodies bind to regions on the antigen called epitopes.
Christian A Balbin, Janelle Nunez-Castilla, Vitalii Stebliankin, Prabin Baral, Masrur Sobhan, Trevor Cickovski, Ananda Mohan Mondal, Giri Narasimhan, Prem Chapagain, Kalai Mathee, Jessica Siltberg-Liberles   +10 more
doaj   +1 more source

Allergens derived from shrimp [PDF]

, 2015
Allergy caused by food is usually type 1 allergy of four types of allergic reactions. One of the most widespread allergic is those that are caused by crustacean shellfish. Crustaceans are classified among arthropods which include crab, crayfish, lobster,
Abdull Razis, Ahmad Faizal, Packiamuthu Dewaprigam Solomen, Mary Margaret, Selamat, Jinap   +2 more
core  

Mutanome and expression of immune response genes in microsatellite stable colon cancer [PDF]

, 2017
The aim of this study was to analyze the impact of the mutanome in the prognosis of microsatellite stable stage II CRC tumors. The exome of 42 stage II, microsatellite stable, colon tumors (21 of them relapse) and their paired mucosa were sequenced and ...
Alemany Bonastre, Ramon, Alonso Aguado, Maria Henar, Aussó, Susanna, Garcia i Molleví, David, Gil Hoyos, Raúl, López Dóriga Guerra, Adriana, Moreno Aguado, Víctor, Salazar Soler, Ramón, Sanjuan, Xavier, Santos, Cristina, Sanz Pamplona, Rebeca   +10 more
core   +1 more source

Benchmarking solutions to the T-cell receptor epitope prediction problem: IMMREP22 workshop report

ImmunoInformatics, 2023
Many different solutions to predicting the cognate epitope target of a T-cell receptor (TCR) have been proposed. However several questions on the advantages and disadvantages of these different approaches remain unresolved, as most methods have only been
Pieter Meysman, Justin Barton, Barbara Bravi, Liel Cohen-Lavi, Vadim Karnaukhov, Elias Lilleskov, Alessandro Montemurro, Morten Nielsen, Thierry Mora, Paul Pereira, Anna Postovskaya, María Rodríguez Martínez, Jorge Fernandez-de-Cossio-Diaz, Alexandra Vujkovic, Aleksandra M. Walczak, Anna Weber, Rose Yin, Anne Eugster, Virag Sharma   +18 more
doaj   +1 more source

Automated benchmarking of peptide-MHC class I binding predictions [PDF]

, 2015
Motivation: Numerous in silico methods predicting peptide binding to major histocompatibility complex (MHC) class I molecules have been developed over the last decades. However, the multitude of available prediction tools makes it non-trivial for the end-
Greenbaum, Jason, Kim, Yohan, Lund, Ole, Metushi, Imir G., Nielsen, Morten, Peters, Bjoern, Sette, Alessandro, Sidney, John, Trolle, Thomas   +8 more
core   +3 more sources

Machine-learning-based analytics for risk forecasting of anaphylaxis during general anesthesia

ImmunoInformatics, 2022
Perioperative anaphylaxis has a risk of mortality and compromised quality of patient care. It is difficult to design an evaluation system for risk of anaphylaxis using preoperative tests available in clinical practice.
Shuang Liu, Yasuyuki Suzuki, Toshihiro Yorozuya, Masaki Mogi   +3 more
doaj   +1 more source

TRain: T-cell receptor automated immunoinformatics. [PDF]

BMC Bioinformatics
The scarcity of available structural data makes characterizing the binding of T-cell receptors (TCRs) to peptide-Major Histocompatibility Complexes (pMHCs) very challenging. The recent surge in sequencing data makes TCRs an ideal target for protein structure modeling. Through these 3D models, researchers can potentially identify key motifs on the TCR's
Seamann A, Bennett-Boehm M, Ehrlich R, Gil A, Selin L, Ghersi D.   +5 more
europepmc   +4 more sources

A Mutation‐Based Reverse Vaccinology Approach Considering Variability in Epitopes to Combat Multi‐Strains: A Study Using Glycoprotein of LASV

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT Lassa virus (LASV) remains a persistent threat to public health, and to combat this, various therapeutics have been developed, but their effectiveness is limited due to the virus's strain variability. Therefore, mutation‐based reverse vaccinology approaches were implemented to formulate an epitope‐based vaccine against the LASV, considering ...
Saurav Kumar Mishra, Rajesh B. Patil, Amdola Tshering Sherpa, Mohammad Borhan Uddin, Md. Harun‐Or‐Rashid, Muniruddin Ahmed, Turki M. Dawoud, John J. Georrge   +7 more
wiley   +1 more source