Results 31 to 40 of about 4,043 (182)
Modeling interaction of Glioma cells and CAR T-cells considering multiple CAR T-cells bindings
ImmunoInformatics, 2023 Chimeric antigen receptor (CAR) T-cell based immunotherapy has shown its potential in treating blood cancers, and its application to solid tumors is currently being extensively investigated.
Runpeng Li +6 more
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Immunoinformatics: A Basic Bibliometric Analysis [PDF]
ImmunoAnalysis, 2021 Background: Traditionally, immunologists have been using experimental methods for a long time, which have generated functional, clinical and epidemiological data. So, it is inevitable to develop and apply novel computational approaches to collect, store, analyze, and report the latent knowledge behind these data.
Elaheh Rahimpour, Taha Samad-Soltani
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ImmunoInformatics, 2022 T cells exercise a multitude of functions such as cytotoxicity, secretion of immunomodulating cytokines or regulation of tolerance, collectively resulting in an effective control of immune-related disease.
Sebastiaan Valkiers +6 more
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ImmunoInformatics, 2023 The COVID-19 pandemic has revealed the need for the increased integration of modelling and data analysis to public health, experimental, and clinical studies.
Sonia Gazeau +7 more
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FRED 2: an immunoinformatics framework for Python [PDF]
Bioinformatics, 2016 Abstract Summary: Immunoinformatics approaches are widely used in a variety of applications from basic immunological to applied biomedical research. Complex data integration is inevitable in immunological research and usually requires comprehensive pipelines including multiple tools and data sources. Non-standard input and output formats
Benjamin Schubert +5 more
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Immunoinformatics: Predicting Peptide–MHC Binding [PDF]
Annual Review of Biomedical Data Science, 2020 Immunoinformatics is a discipline that applies methods of computer science to study and model the immune system. A fundamental question addressed by immunoinformatics is how to understand the rules of antigen presentation by MHC molecules to T cells, a process that is central to adaptive immune responses to infections and cancer.
Nielsen, Morten +3 more
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AntigenDB: an immunoinformatics database of pathogen antigens [PDF]
Nucleic Acids Research, 2009 The continuing threat of infectious disease and future pandemics, coupled to the continuous increase of drug-resistant pathogens, makes the discovery of new and better vaccines imperative. For effective vaccine development, antigen discovery and validation is a prerequisite.
Hifzur Rahman Ansari +2 more
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Immunoinformatics and tick vaccinology
Exploration of Immunology, 2023 Immunoinformatics is an emerging area focused on development and applications of methods used to facilitate vaccine development. There is a growing interest in the field of vaccinology centered on the new omic science named ‘vaccinomics’. However, this approach has not succeeded to provide a solution against major infections affecting both animals and ...
Rodrigo Rosario-Cruz +3 more
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Immunoinformatics and Vaccine Development: An Overview.
ImmunoTargets and therapy, 2020 The use of vaccines have resulted in a remarkable improvement in global health. It has saved several lives, reduced treatment costs and raised the quality of animal and human lives. Current traditional vaccines came empirically with either vague or completely no knowledge of how they modulate our immune system.
Oli,Angus Nnamdi +7 more
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IMGT-ONTOLOGY for immunogenetics and immunoinformatics.
In silico biology, 2003 IMGT, the international ImMunoGeneTics information system(R) (http://imgt.cines.fr), is a high quality integrated knowledge resource specializing in immunoglobulins (IG), T cell receptors (TR), major histocompatibility complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrates, created in 1989, by the Laboratoire d ...
Lefranc, Marie-Paule +19 more
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