BMC BioinformaticsBackground The emergence of HIV drug resistance is a challenge in controlling the acquired immunodeficiency syndrome (AIDS) pandemic caused by human immunodeficiency virus-1 (HIV-1) infection.
Thoai Dotrang +10 more
doaj +1 more source
Mycobacterium tuberculosis Complex Exhibits Lineage-Specific Variations Affecting Protein Ductility and Epitope Recognition [PDF]
, 2016 The advent of whole-genome sequencing has provided an unprecedented detail about the evolution and genetic significance of species-specific variations across the whole Mycobacterium tuberculosis Complex.
Contreras-Moreira, Bruno +4 more
core +2 more sources
Bioinformatics and immunoinformatics to support COVID‐19 vaccine development [PDF]
, 2021 Stephanie Ishack, Shari R. Lipner
openalex +1 more source
Protein Science, Volume 34, Issue 9, September 2025.Abstract In this study, we analyzed large‐scale T‐cell receptor (TCR) sequence data to determine whether TCRs preferentially bind to major histocompatibility complex (MHC) class I (CD8+) or class II (CD4+) epitopes. Using the International ImMunoGeneTics information system numbering scheme, we identified specific positions with distinct amino acid ...
Marcus De Almeida Mendes +5 more
wiley +1 more source
ImmunoInformatics, 2023 Protein folding problem obtained a practical solution recently, owing to advances in deep learning. There are classes of proteins though, such as antibodies, that are structurally unique, where the general solution still lacks.
Jarosław Kończak +6 more
doaj +1 more source
The CHARME "Advanced Big Data Training School for Life Sciences": an example of good practices for training on current bioinformatics challenges [PDF]
, 2019 The CHARME “Advanced Big Data Training School for Life Sciences” took place during 3-7 September 2018, at the Campus Nord of the Technical University of Catalonia (UPC) in Barcelona (ES).
Duarte López, Ariel +8 more
core +2 more sources
Designing and Modelling of Trivalent Chimeric Vaccine for Capripoxvirus: Lumpy Skin Disease, Sheep Pox and Goat Pox by Immunoinformatics Approach [PDF]
, 2022 M. Pashupathi +6 more
openalex +1 more source
Comparative Genomics of Two Sequential Candida glabrata Clinical Isolates. [PDF]
, 2017 <i>Candida glabrata</i> is an important fungal pathogen which develops rapid antifungal resistance in treated patients. It is known that azole treatments lead to antifungal resistance in this fungal species and that multidrug efflux ...
Beaudoing, E. +3 more
core +2 more sources
In silico designing of a novel polyvalent multi-subunit peptide vaccine leveraging cross- immunity against human visceral & cutaneous leishmaniasis: An Immunoinformatics-based approach [PDF]
, 2022 Mainak Bhattacharjee +2 more
openalex +1 more source
Role of NTRK Fusion Genes in the Tumor Immune Microenvironment of HPV (+/−) Cervical Cancer
Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT Cervical cancer, a prevalent gynecological malignancy, is primarily associated with human papillomavirus (HPV) infection. However, some cases display distinct molecular alterations beyond HPV, significantly impacting the tumor immune microenvironment (TIME) and posing therapeutic challenges.
Qiongying Wang +7 more
wiley +1 more source