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T Cells Immunology in the Immunological Diseases [PDF]

open access: yesJournal of Immunology Research, 2014
Immunological diseases, with the morbidity keeping increased, have become a major threat to human mental and physical health. However, the pathogenesis of these diseases is extremely complicated and remains unclear. Recent advances in biology have introduced new technologies to study the underlying mechanisms that contribute to the development of ...
Qifa Liu   +3 more
openaire   +3 more sources

The Ambiguity in Immunology [PDF]

open access: yesFrontiers in Immunology, 2012
In the present article, we discuss the various ambiguous aspects of the immune system that render this complex biological network so highly flexible and able to defend the host from different external invaders. This ambiguity stems mainly from the property of the immune system to be both protective and harmful.
BARNABA, Vincenzo   +2 more
openaire   +5 more sources

Leptin in Immunology [PDF]

open access: yesThe Journal of Immunology, 2005
AbstractLeptin is an adipokine which conveys information on energy availability. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. As a cytokine, leptin also affects thymic homeostasis and, similar to other proinflammatory cytokines, leptin promotes Th1 cell differentiation ...
MATARESE, GIUSEPPE   +2 more
openaire   +7 more sources

On the crossroad between tolerance and posttransplant lymphoma. [PDF]

open access: yes, 1997
The role of the Epstein-Barr virus in the development of post-transplant lymphomas is well established. However, not all lymphomas that arise in these patients contain Epstein-Barr virus, suggesting that other cofactors are involved in tumor pathogenesis.
Nalesnik, Michael A, Starzl, Thomas E
core   +1 more source

Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. [PDF]

open access: yes, 2017
BACKGROUND: Delayed immunologic aging is purported to be a major mechanism through which calorie restriction (CR) exerts its anti-aging effects in non-human species.
Epel, Elissa S   +8 more
core   +3 more sources

IMMUNOLOGY OF TUBERCULOSIS [PDF]

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
MTB ranks as the first worldwide pathogen latently infecting one third of the population and the second leading cause of death from a single infectious agent, after the human immunodeficiency virus (HIV). The development of vigorous and apparently appropriate immune response upon infection with M.tuberculosis in humans and experimental animals conflict
Bozzano F, Marras F, DE MARIA, ANDREA
openaire   +4 more sources

Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort [PDF]

open access: yes, 2018
BACKGROUND: Globally, 49% of the estimated 1.8 million children living with HIV are accessing antiretroviral therapy (ART). There are limited data concerning long-term durability of first-line ART regimens and time to transition to second-line ...
Ayaya, Samuel   +16 more
core   +2 more sources

The changing immunology of organ transplantation [PDF]

open access: yes, 1995
The engrafted organ becomes a chimera as the recipient's leukocytes station themselves in the transplant. Remarkably, the recipient becomes chimeric as well, in a reverse migration involving immune cells from the graft.
Demetris AJ   +10 more
core   +1 more source

The Immunological Synapse [PDF]

open access: yesCancer Immunology Research, 2003
AbstractThe molecular interactions underlying regulation of the immune response take place in a nanoscale gap between T cells and antigen-presenting cells, termed the immunological synapse. If these interactions are regulated appropriately, the host is defended against a wide range of pathogens and deranged host cells.
openaire   +8 more sources

Comparative Immunology [PDF]

open access: yesIntegrative and Comparative Biology, 1985
AbstractAs a discipline, comparative immunology enhances zoology and has gained wide acceptance in the biological sciences. It is an offshoot of the parent field, immunology, and is an amalgam of immunology and zoology. All animals from protozoans to humans have solved the threat of extinction by having evolved an immune‐defense strategy that ensures ...
openaire   +6 more sources

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