Results 11 to 20 of about 720,178 (345)

Clinical and immunologic features in severe and moderate Coronavirus Disease 2019.

open access: yesJournal of Clinical Investigation, 2020
BACKGROUND Since December 2019, an outbreak of Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, and is now becoming a global threat.
Guang Chen   +19 more
semanticscholar   +1 more source

T Cells Immunology in the Immunological Diseases [PDF]

open access: yesJournal of Immunology Research, 2014
Immunological diseases, with the morbidity keeping increased, have become a major threat to human mental and physical health. However, the pathogenesis of these diseases is extremely complicated and remains unclear. Recent advances in biology have introduced new technologies to study the underlying mechanisms that contribute to the development of ...
Qifa Liu   +3 more
openaire   +3 more sources

Immunologic Effects of Vitamin D on Human Health and Disease

open access: yesNutrients, 2020
Vitamin D is responsible for regulation of calcium and phosphate metabolism and maintaining a healthy mineralized skeleton. It is also known as an immunomodulatory hormone.
N. Charoenngam, M. Holick
semanticscholar   +1 more source

The Ambiguity in Immunology [PDF]

open access: yesFrontiers in Immunology, 2012
In the present article, we discuss the various ambiguous aspects of the immune system that render this complex biological network so highly flexible and able to defend the host from different external invaders. This ambiguity stems mainly from the property of the immune system to be both protective and harmful.
BARNABA, Vincenzo   +2 more
openaire   +5 more sources

Leptin in Immunology [PDF]

open access: yesThe Journal of Immunology, 2005
AbstractLeptin is an adipokine which conveys information on energy availability. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. As a cytokine, leptin also affects thymic homeostasis and, similar to other proinflammatory cytokines, leptin promotes Th1 cell differentiation ...
MATARESE, GIUSEPPE   +2 more
openaire   +7 more sources

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.

open access: yesJournal of Clinical Investigation, 1973
Endothelial cells were isolated from freshly obtained human umbilical cords by collagenase digestion of the interior of the umbilical vein. The cells were grown in tissue culture as a homogeneous population for periods up to 5 mo and some lines were ...
E. Jaffe   +3 more
semanticscholar   +1 more source

Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates.

open access: yesJournal of Clinical Oncology, 2010
PURPOSE Programmed death-1 (PD-1), an inhibitory receptor expressed on activated T cells, may suppress antitumor immunity. This phase I study sought to determine the safety and tolerability of anti-PD-1 blockade in patients with treatment-refractory ...
J. Brahmer   +19 more
semanticscholar   +1 more source

The Effects of Honey Sulfonamides on Immunological and Hematological Parameters in Wistar Rats

open access: yesMedicina, 2022
Sulfonamides are among the most used drugs in beekeeping due to their effectiveness, despite their long-term persistence in tissues. Bee honey containing such residues poses numerous risks to human health. The aim of the study was to evaluate the effects
Ionela Daniela Morariu   +5 more
doaj   +1 more source

Topology and adenocarcinoma cell localization dataset on the labyrinthin diapeutic biomarker

open access: yesBMC Research Notes, 2023
Objective The discovery and characterization of tumor associated antigens is increasingly important to advance the field of immuno-oncology. In this regard, labyrinthin has been implicated as a neoantigen found on the cell surface of adenocarcinomas ...
Ankit Sharma   +3 more
doaj   +1 more source

The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis

open access: yesClinical reviews in allergy and immunology, 2018
Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17, the major effector cytokine in the pathogenesis of psoriatic ...
A. Blauvelt, A. Chiricozzi
semanticscholar   +1 more source

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