Immunologic incompetence of immunologically runted animals [PDF]
1. Adult (A x C57Bl/1)F1 hybrids regularly show runt disease when injected with adult spleen cells from A strain donors. This also occurs when A strain spleen cells are administered to adult C3H mice made tolerant of A strain tissue in the neonatal period. 2.
Blaese, R M, Martinez, C, Good, R A
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The Biological Influence and Clinical Relevance of Polymorphism Within the NKG2D Ligands
NKG2D is a major regulator of the activity of cytotoxic cells and interacts with eight different ligands (NKG2DL) from two families of MIC and ULBP proteins.
Jianmin Zuo, Fiyaz Mohammed, Paul Moss
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Vaccination for Respiratory Syncytial Virus: A Narrative Review and Primer for Clinicians
Respiratory syncytial virus (RSV) poses a significant burden on public health, causing lower respiratory tract infections in infants, young children, older adults, and immunocompromised individuals.
Kay Choong See
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A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo
Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Hannah E. Scales +10 more
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Modeling of endothelial cell dysfunction using human induced pluripotent stem cells derived from patients with end-stage renal disease [PDF]
Background Endothelial cell (EC) dysfunction is a frequent feature in patients with end-stage renal disease (ESRD). The aim of this study was to generate human induced pluripotent stem cells, differentiate ECs (hiPSC-ECs) from patients with ESRD, and ...
Kyoung Woon Kim +7 more
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Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males [PDF]
Purpose: Proprotein convertase subtilisin/kexin type 4 (PCSK4, a 54-kDa protease) is expressed in the plasma membrane of the acrosome in human spermatozoa. It plays a critical role in penetrating the zona pellucida. Synthesis of human anti-PCSK4 might be
Dahril +3 more
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Assessment of intracanal medications cytotoxicity on L929 fibroblast cells
This study aimed to evaluate the cytotoxicity of intracanal medications on L929 fibroblast cells at different periods of observation. The following experimental groups were studied: calcium hydroxide with camphorated paramonochlorophenol and glycerin ...
Michelle de Paula Farias +6 more
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This editorial introduces several review articles focused on cytomegalovirus, including immune response to this virus, congenital cytomegalovirus infection, vaccines etc. All these articles are part of the special issue published in Cellular and Molecular Immunology.
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Morphologic Spectrum of Undetermined Causes of Hemoptysis- A Pathologist's Role
Objective: Hemoptysis is the expectoration of blood or blood-streaked sputum from the tracheobronchial tree. The etiology may derive from nonneoplastic conditions such as infections, chronic pulmonary diseases, and vasculitis or neoplastic causes ...
Nidhya GANESAN, Umamaheswari GURUSAMY
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AbstractAs a discipline, comparative immunology enhances zoology and has gained wide acceptance in the biological sciences. It is an offshoot of the parent field, immunology, and is an amalgam of immunology and zoology. All animals from protozoans to humans have solved the threat of extinction by having evolved an immune‐defense strategy that ensures ...
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