Results 31 to 40 of about 295,741 (152)

Seasonal Influenza Split Vaccines Confer Partial Cross-Protection against Heterologous Influenza Virus in Ferrets When Combined with the CAF01 Adjuvant

Frontiers in Immunology, 2018
Influenza epidemics occur annually, and estimated 5–10% of the adult population and 20–30% of children will become ill from influenza infection. Seasonal vaccines primarily work through the induction of neutralizing antibodies against the principal ...
Dennis Christensen, Jan P. Christensen, Karen S. Korsholm, Louise K. Isling, Karin Erneholm, Allan R. Thomsen, Peter Andersen   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

MCP‐1 Is Elevated in the Cerebral Fluid of Children With Tourette Syndrome: Case Series and Literature Review

Brain and Behavior
Purpose This study aims to investigate cerebrospinal fluid (CSF) in patients with Tourette syndrome (TS) to identify the role of neuroinflammation in the pathophysiology of TS.
Ke Zhongling, Chen Mengxin, Huang Yuxian, Chen Yanhui   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

In Vitro Analysis of the Proliferation of HaCaT Cells Stimulated by Pigments Used for Maxillofacial Prostheses

Journal of Orofacial Sciences, 2019
Introduction: Although physical and mechanical properties are extremely important for the effectiveness of prosthetic treatment, materials used for facial rehabilitation should be biocompatible, as the maxillofacial prosthesis is in close contact with ...
Marcelo Coelho Goiato, Adhara Smith Nobrega, Estefania Marrega Malavazi, Aline Satie Takamiya, Sandra Helena Penha de Oliveira   +4 more
doaj   +1 more source

Citotoxicidad del glifosato en células mononucleares de sangre periférica humana

Biomédica: revista del Instituto Nacional de Salud, 2007
Introducción. El glifosato es un herbicida de amplio espectro, no selectivo, utilizado comúnmente en agricultura para eliminar malezas. Los estudios que han evaluado la toxicidad del glifosato en animales y en ambiente muestran que las formulaciones ...
Adriano Martínez, Ismael Reyes, Niradiz Reyes   +2 more
doaj   +1 more source

PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis

Nature Communications, 2021
Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell ...
Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner   +18 more
doaj   +1 more source

Labyrinthin: A distinct pan-adenocarcinoma diagnostic and immunotherapeutic tumor specific antigen

Heliyon, 2022
Structural analysis and detection of optimal cell surface localization of labyrinthin, a pan-adenocarcinoma target, was studied with respect to adenocarcinoma specificity vs. normal and non-adenocarcinoma cells.
Michael Babich, Ankit Sharma, Tianhong Li, James A. Radosevich   +3 more
doaj   +1 more source

A Cost-Utility Analysis of SQ® Tree SLIT-Tablet versus Placebo in the Treatment of Birch Pollen Allergic Rhinitis from a Swedish Societal Perspective

ClinicoEconomics and Outcomes Research, 2023
Richard F Pollock,1 Andreas K Slættanes,2 Henrik Brandi,2 Tobias Sydendal Grand2 1Covalence Research Ltd, Harpenden, UK; 2ALK-Abelló A/S, Hørsholm, DenmarkCorrespondence: Andreas K Slættanes, ALK-Abelló A/S, Bøge Allé 1, Hørsholm, DK-2970, Denmark, Tel ...
Pollock RF, Slættanes AK, Brandi H, Grand TS   +3 more
doaj  

Potential effects of Linh Loc Son hard capsule – a Vietnamese herbal combination in immunodeficiency induced by cyclophosphamide on mice [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Traditional medicine and herbal extracts have long been recognized for their immunomodulatory effects, enhancing patient immune responses. The use of traditional medicine to target specific pathogens and support the immune system is increasingly
Binh Quoc Pham, Ngan Kim Thi Nguyen, Su Quoc Pham, Cuong Duy Nguyen, Lam Vu Trinh, Hang Thu Thi Dinh, Quang Vinh Trinh, Van Anh Thi Pham   +7 more
doaj   +1 more source