Results 101 to 110 of about 125,515 (325)
J. Nachega+7 more
semanticscholar +1 more source
The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang+16 more
wiley +1 more source
Immunologic studies in asymptomatic hemophilia patients. Relationship to acquired immune deficiency syndrome (AIDS). [PDF]
Alan Landay+5 more
openalex +1 more source
Pathogenic mechanisms and clinical implications of congenital neutropenia syndromes
F. Hauck, C. Klein
semanticscholar +1 more source
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou+15 more
wiley +1 more source
J. E. Hart+6 more
semanticscholar +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
V. Triant+5 more
semanticscholar +1 more source
Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser+20 more
wiley +1 more source