Results 101 to 110 of about 25,675 (362)

Immunodeficiency in cartilage-hair hypoplasia : Pathogenesis, clinical course and management [PDF]

, 2020
Cartilage-hair hypoplasia (CHH) is an autosomal recessive syndromic immunodeficiency with skeletal dysplasia, short stature, hypotrichosis, variable degree of immune dysfunction and increased incidence of anaemia, Hirschsprung disease and malignancy. CHH
Mäkitie, Outi, Taskinen, Mervi, Vakkilainen, Svetlana   +2 more
core   +1 more source

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

Advanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch, Brittany Scheid, Kathryn A Davis, Brian Litt, Arian Ashourvan   +4 more
wiley   +1 more source

Assessment of the effect of a protein calorie supplement on change in CD4 count among art-naïve female TB patients co-infected with HIV in Dar Es Salaam, Tanzania [PDF]

, 2017
RATIONALE: Tuberculosis and HIV infection together form a highly mortal combination. Even after the advent of highly active antiretroviral therapy (HAART) medications, management for Tuberculosis and HIV/AIDS still remains a challenge. Poor outcomes (in
Magohe, Albert Katana
core   +1 more source

Cell migration and chimerism after whole‐organ transplantation: The basis of graft acceptance [PDF]

, 1993
Improvements in the prevention or control of rejection of the kidney and liver have been largely interchangeable ( 1 , 2 ) and then applicable, with very little modification, to thoracic and other organs.
Demetris, AJ, Fung, JJ, Ildstad, S, Kocova, M, Murase, N, Nalesnik, M, Ramos, H, Ricordi, C, Rudert, WA, Starzl, TE, Todo, S, Trucco, M, Tzakis, A, Zeevi, A   +13 more
core   +1 more source

Advancing Allogeneic NK Cell Immunotherapy through Microfluidic Gene Delivery

Advanced Science, EarlyView.
The Y‐Hydroporator is a microfluidic gene delivery platform designed for allogeneic NK cell‐based immunotherapies. It achieves highly efficient gene delivery while preserving high cell viability and functionality. By producing engineered NK cells with enhanced cytotoxicity, the platform addresses critical limitations of autologous cell therapy ...
Hyelee Kim, Mujin Lee, Bohwa Han, Jinho Kim, Duck Cho, Junsang Doh, Aram J. Chung   +6 more
wiley   +1 more source

Older patients with COVID‐19 and neuropsychiatric conditions: A study of risk factors for mortality

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Little is known about risk factors for mortality in older patients with COVID‐19 and neuropsychiatric conditions. Methods We conducted a multicentric retrospective observational study at Assistance Publique‐Hôpitaux de Paris. We selected inpatients aged 70 years or older, with COVID‐19 and preexisting neuropsychiatric comorbidities
Vi‐Huong Nguyen‐Michel, Marion Houot, Cécile Delorme, Aude Sangaré, Ana Gales, Valerio Frazzini, Aurélie Hanin, Djamal Aissani, Thanh Trân, Bruno Oquendo, Flora Ketz, Carmelo Lafuente‐Lafuente, Christel Oasi, Kiyoka Kinugawa, Gaëlle Ouvrard, Renata Ursu, Bertrand Degos, Benjamin Rohaut, Sophie Demeret, Virginie Lambrecq, Vincent Navarro, Emmanuel Fournier, Jean‐Christophe Corvol, Alaina Borden   +23 more
wiley   +1 more source

A novel case of chronic mucocutaneous candidiasis: Overlap between autoimmune polyendocrinopathy, candidiasis, ectodermal dystrophy syndrome and hyper IgE syndrome

Indian Journal of Paediatric Dermatology, 2018
Chronic mucocutaneous candidiasis (CMC) is a clinical entity where extensive fungal infection of skin, hair, nail, and mucosa with Candida sp. is seen. It has got association with several immunological and endocrinal dysfunctions.
Bauyelal Mahto, Payel Kundu, Aniruddha Ghosh, Sandipan Dhar   +3 more
doaj   +1 more source

A comparison of the cytogenetic, clinical, and immunologic aspects of four "chromosome breakage syndromes" : ataxia telangiectasia, Bloom's syndrome, Fanconi's anemia and xeroderma pigmentosum [PDF]

, 1977
Some rare autosomal recessive diseases of humans have been reported to have in common a high frequency of spontaneous chromosome aberrations, developmental abnormalities, and a predisposition to malignancy. The three diseases most frequently mentioned in
Adams, Nancy J, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children [PDF]

, 2011
Background There are limited data of immunologic and virologic failure in Asian HIV-infected children using non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral therapy (HAART).
Ananworanich, Jintanat, Boonrak, Pitch, Bunupuradah, Torsak, Kerr, Stephen, Kosalaraksa, Pope, Lumbiganon, Pagakrong, Mengthaisong, Tawan, Pancharoen, Chitsanu, Phasomsap, Chayapa, Prasitsuebsai, Wasana, Puthanakit, Thanyawee, Ruxrungtham, Kiat   +11 more
core   +3 more sources

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

Advanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu, Qing Ma, Yunhui Kong, Zhaoyue Wang, Minglu Xu, Xiangyi Chen, Yajuan Su, Tinghui Xiao, Qing He, Xuan Wang, Wenjun Xu, Yiling Yang, Xushu Wang, Xiaobo Li, Yanfang Liu, Shuangshuang Chen, Rui Zhao, Meng Guo, Gaowei Wang, Weida Li   +19 more
wiley   +1 more source