Results 111 to 120 of about 125,515 (325)

Characterization of immunologic function in homosexual men with persistent, generalized lymphadenopathy and acquired immune deficiency Syndrome

, 1987
Ronald L. Burkes, Wataru Abo, Alexandra M. Levine, Mariana Linker‐Israeli, Jōhn W. Parker, Parkash S. Gill, Mark Krailo, David A. Horwitz   +7 more
openalex   +1 more source

CXCR1 Depletion in Ly6C+ cDC2 Alleviates Acute Lung Injury via Modulation of Th17/Treg Balance

Advanced Science, EarlyView.
Pro‐inflammatory Ly6C⁺ cDC2s are identified as key effector cells mediating Cxcr1 signaling, driving the progression of ALI. Ly6C⁺ cDC2s release high levels of Il‐6 and Il‐1β, inducing Th17 differentiation. Cxcr1 deficiency reduces Il‐6 and Il‐1β production from Ly6C⁺ cDC2s through suppressing MEK1/ERK /NF‐κB signaling, thereby shifts naïve T cells ...
Shenghui Li, Wei Zhuang, Yang Wang, Hao Qin, Xichun Qin, Xianliang Yan, Xuefei Hu, Xiucheng Liu, Chang Chen   +8 more
wiley   +1 more source

Clinical Manifestations, Etiology, and Pathogenesis of the Hyper-IgE Syndromes

Pediatric Research, 2009
A. Freeman, S. Holland
semanticscholar   +1 more source

Bispecific Nanosystems Enable Multieffector Immune Cell Retargeting for Hematologic Malignancy Therapy

Advanced Science, EarlyView.
B‐cell lymphomas are aggressive malignancies with limited treatment options. A bispecific nanosystem (biHSNPs) is developed, leveraging silica nanoplatforms to conjugate antibodies targeting immune effector cells and B‐cell antigens. biHSNPs form artificial immunological synapses, activating cytotoxic responses and suppressing tumor proliferation. This
Yefeng Shen, Xin Li, Jingnan Wu, Yuru Ma, Sven Borchmann, Zhenguo Cheng, Yaohe Wang, Yongliang Zhao, Jian Song, Boyu Luo, Xiuyun Liu, Yue Teng, Zhiyuan Shi   +12 more
wiley   +1 more source

Immunologic and Virologic Predictors of AIDS-Related Non-Hodgkin Lymphoma in the Highly Active Antiretroviral Therapy Era

Journal of Acquired Immune Deficiency Syndromes, 2009
E. Engels, R. Pfeiffer, O. Landgren, Richard D. Moore   +3 more
semanticscholar   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

Advanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Clinical Outcome of HIV-Infected Antiretroviral-Naive Patients With Discordant Immunologic and Virologic Responses to Highly Active Antiretroviral Therapy

Journal of Acquired Immune Deficiency Syndromes, 2008
Ruimin Tan, A. Westfall, J. Willig, M. Mugavero, M. Saag, R. Kaslow, M. Kempf   +6 more
semanticscholar   +1 more source

Aptamer‐Mediated Artificial Synapses for Neuromorphic Modulation of Inflammatory Signaling via Organic Electrochemical Transistor

Advanced Science, EarlyView.
An aptamer‐mediated neuromorphic interface based on organic electrochemical transistors selectively transduces interleukin‐6 (IL‐6) signals into neuromorphic electrical outputs. This protein‐driven neuromorphic plasticity, responsive in physiological and in vivo environmental electrolyte, bridges biochemical signaling with artificial neural encoding ...
Yuqing Ding, You Kuai, Rongpei Li, Xinzhao Xu, Bo Wang, Zhihui Wang, Yanfang Liu, Yuchao Dong, Shunjie Chen, Meng Guo, Yunqi Liu, Yan Zhao   +11 more
wiley   +1 more source

Artificial Intelligence‐Driven Proteomics Identifies Plasma Protein Signatures for Diagnosis and Stratification of Behçet's Disease

Advanced Science, EarlyView.
Molecular and functional landscape of BD progression and severity based on in‐depth proteomics. Tree boosting machine learning models with favorable performance in BD diagnosis and stratification. Efficient biomarker panels for BD diagnosis and stratification. .
Linlin Cheng, Mansheng Li, Zhou Bai, Xiaobo Yu, Wenjie Zheng, Yongzhe Li, Yudong Liu   +6 more
wiley   +1 more source

Síndrome mielodisplásico: I. Biología y clínica Myelodysplastic syndrome: I. Biology and Clinic

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2000
Los síndromes mielodisplásicos (SMD) constituyen un grupo de trastornos clonales caracterizados por citopenias progresivas y dishematopoyesis.
Norma Fernández Delgado, Porfirio Hernández Ramírez   +1 more
doaj