Results 11 to 20 of about 142,171 (218)

Primary Immune Regulatory Disorders With an Autoimmune Lymphoproliferative Syndrome-Like Phenotype: Immunologic Evaluation, Early Diagnosis and Management

Frontiers in Immunology, 2021
Primary immune regulatory disorders (PIRD) are associated with autoimmunity, autoinflammation and/or dysregulation of lymphocyte homeostasis. Autoimmune lymphoproliferative syndrome (ALPS) is a PIRD due to an apoptotic defect in Fas-FasL pathway and ...
Marta López-Nevado, L. González-Granado, R. Ruiz-García, D. Pleguezuelo, O. Cabrera-Marante, N. Salmón, P. Blanco-Lobo, N. Domínguez-Pinilla, R. Rodríguez‐Pena, E. Sebastián, J. Cruz-Rojo, P. Olbrich, J. Ruiz-Contreras, E. Paz-Artal, O. Neth, L. Allende   +15 more
semanticscholar   +1 more source

Discordant Immune Response with Antiretroviral Therapy in HIV-1: A Systematic Review of Clinical Outcomes. [PDF]

, 2016
BACKGROUND A discordant immune response (DIR) is a failure to satisfactorily increase CD4 counts on ART despite successful virological control. Literature on the clinical effects of DIR has not been systematically evaluated.
Garner, Paul, Gaskell, Katherine M., Kelly, Christine, Klein, Nigel, Landay, Alan, MacPherson, Peter, Richardson, Marty   +6 more
core   +16 more sources

Pattern and Predictors of Weight Gain During Pregnancy Among HIV-1-Infected Women from Tanzania [PDF]

, 2003
Progression of HIV disease is often accompanied by weight loss and wasting. Gestational weight gain is a strong determinant of maternal and neonatal outcomes; however, the pattern and predictors of weight gain during pregnancy among HIV-positive women ...
Antelman, Gretchen, Fawzi W., Wafaie, Msamanga, Gernard, Peterson E., Karen, Spiegelman, Donna, Villamor, Eduardo   +5 more
core   +1 more source

Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes.

Blood, 2008
TNFRSF13B encodes transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), a B cell- specific tumor necrosis factor (TNF) receptor superfamily member.
U. Salzer, C. Bacchelli, S. Buckridge, Q. Pan-Hammarström, Stephanie Jennings, V. Lougaris, A. Bergbreiter, T. Hagena, Jennifer Birmelin, A. Plebani, A. Webster, H. Peter, D. Suez, H. Chapel, A. Mclean-Tooke, G. Spickett, Stephanie Anover-Sombke, H. Ochs, S. Urschel, B. Belohradsky, S. Ugrinovic, D. Kumararatne, T. C. Lawrence, A. Holm, J. Franco, I. Schulze, P. Schneider, E. Gertz, A. Schäffer, L. Hammarström, A. Thrasher, H. Gaspar, B. Grimbacher   +32 more
semanticscholar   +1 more source

Correlation between Traditional Chinese Medicine Symptom Patterns and the Renal Function, Immunologic Function Index, and Blood Coagulation Index in Patients with Henoch-Schönlein Purpura Nephritis

Evidence-Based Complementary and Alternative Medicine, 2018
Objective We investigate the correlation between the patterns of traditional Chinese medicine (TCM) syndromes and the damage of renal function, immunologic function index, and blood coagulation index in patients with Henoch-Schönlein purpura nephritis ...
Wanyu Dang, Huimin Yan, Xiaoming Wu, Xiaofang Zhen, Linyi Hou   +4 more
semanticscholar   +1 more source

22q11.2 deletion syndrome [PDF]

, 2015
22q11.2 deletion syndrome (22q11.2DS) is the most common chromosomal microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic recombination events occurring in approximately 1 in every 1,000 fetuses. The first description in
Bassett, Anne S., Emanuel, Beverly S., Marino, Bruno, McDonald-McGinn, Donna M., Morrow, Bernice E., Philip, Nicole, Scambler, Peter J., Sullivan, Kathleen E., Swillen, Ann, Vermeesch, Joris R., Vorstman, Jacob A. S., Zackai, Elaine H.   +11 more
core   +1 more source

Liver transplantation for type IV glycogen storage disease [PDF]

, 1991
TYPE IV glycogen storage disease is a rare autosomal recessive disorder (also called Andersen's disease1 or amylopectinosis) in which the activity of branching enzyme alpha-1, 4-glucan: alpha-1, 4-glucan 6-glucosyltransferase is deficient in the liver as
Andreas Tzakis, Bannayan, Barbara I. Brown, Brown, Eduardo Yunis, Greene, Illingworth, Ishihara, Ishihara, Mazzaferro, McMaster, Reed, Rick Selby, Ross S. Kendall, Schochet, Stand, Starzl, Thomas E. Starzl   +17 more
core   +1 more source

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue [PDF]

Science Translational Medicine, American Association for the Advancement of Science, 2017, 9 (405), pp.eaal5088, 2017
Dengue is the most prevalent arthropod-borne viral disease. Clinical symptoms of dengue virus (DENV) infection range from classical mild dengue fever to severe, life-threatening dengue shock syndrome. However, most DENV infections cause few or no symptoms.
arxiv   +1 more source

High risk of HIV-related mortality is associated with selenium deficiency.

Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology, 1997
To determine the independent contribution of specific immunologic and nutritional factors on survival in HIV-1 disease, CD4 cell count, antiretroviral treatment, plasma levels of vitamins A, E, B6, and B12 and minerals selenium and zinc were considered ...
M. Baum, G. Shor‐Posner, S. Lai, Guoyan Zhang, H. Lai, M. Fletcher, H. Sauberlich, J. Page   +7 more
semanticscholar   +1 more source

The changing immunology of organ transplantation [PDF]

, 1995
The engrafted organ becomes a chimera as the recipient's leukocytes station themselves in the transplant. Remarkably, the recipient becomes chimeric as well, in a reverse migration involving immune cells from the graft.
Demetris AJ, Lu L, Lu L, Murase N, Starzl TE, Starzl TE, Starzl TE, Starzl TE, Steinman RM, Streilein JW, Thomas JM   +10 more
core   +1 more source