Results 11 to 20 of about 25,675 (362)

A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls, Abel Torres‐Espin, Marc Tormo, Laura Martínez‐Escardó, Núria Bonet, Ferran Casals, Xavier Navarro, Víctor J. Yuste, Esther Udina, Jordi Bruna   +9 more
wiley   +1 more source

Association between primary immunodeficiency and asthma exacerbation in adult asthmatics [PDF]

The Korean Journal of Internal Medicine, 2020
Background/Aims Primary immunodef iciency (PID) is a serious comorbid condition in adult asthmatics that have frequent exacerbations, which requires monthly replacement of intravenous immunoglobulin (IVIG).
So-Hee Lee, Ga-Young Ban, Su-Chin Kim, Chang-Gyu Chung, Hyun-Young Lee, Ji-Ho Lee, Hae-Sim Park   +6 more
doaj   +1 more source

Safety and efficacy of elapegademase in patients with adenosine deaminase deficiency: A multicenter, open‐label, single‐arm, phase 3, and postmarketing clinical study

Immunity, Inflammation and Disease, 2023
Introduction Adenosine deaminase (ADA) deficiency is an ultrarare inherited purine metabolism disorder characterized by severe combined immunodeficiency. Elapegademase‐lvlr is a new pegylated recombinant bovine ADA used in enzyme‐replacement therapy (ERT)
Masafumi Onodera, Toru Uchiyama, Tadashi Ariga, Masafumi Yamada, Takako Miyamura, Hironori Arizono, Tomohiro Morio   +6 more
doaj   +1 more source

Disseminated Postnatal Cytomegalovirus Infection in a Preterm Neonate: Autopsy Case Report [PDF]

Neonatal Medicine, 2021
Treatment guidelines for postnatal cytomegalovirus (pCMV) infection in preterm have not been established yet. Neutropenia, thrombocytopenia, hepatitis, colitis, and sepsis-like disease are among the clinical manifestations, which range from moderate to ...
Ka-Young Kim, Ee-Kyung Kim, Sung-Hye Park, Yoo Jinie Kim, Seung-Han Shin, Han-Suk Kim   +5 more
doaj   +1 more source

Hyperimmunoglobulin E Syndrome with Tortuous and Massively Dilated Thoracic and Abdominal Aorta: An Extremely Rare Cardiac Presentation of an Immunodeficiency Disease

Journal of Tehran University Heart Center, 2020
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Alireza Golbabaei, Behdad Gharib
doaj   +1 more source

Knowledge and clinical practices of orthodontists regarding the treatment of patients with AIDS

Brazilian Journal of Oral Sciences, 2021
Aim: To evaluate orthodontists’ knowledge and clinical practices regarding the treatment of patients with HIV/AIDS. Methods: Cross-sectional study performed with 655 Brazilian orthodontists based on a previously calculated sample size.
Elisabete S. Rocha, Mario Vedovello Filho, Giovana Cherubini Venezian, Carolina Carmo de Menezes, Silvia Amélia Scudeler Vedovello   +4 more
doaj   +1 more source

Pattern and Predictors of Weight Gain During Pregnancy Among HIV-1-Infected Women from Tanzania [PDF]

, 2003
Progression of HIV disease is often accompanied by weight loss and wasting. Gestational weight gain is a strong determinant of maternal and neonatal outcomes; however, the pattern and predictors of weight gain during pregnancy among HIV-positive women ...
Antelman, Gretchen, Fawzi W., Wafaie, Msamanga, Gernard, Peterson E., Karen, Spiegelman, Donna, Villamor, Eduardo   +5 more
core   +1 more source

Immunotherapeutic Biologic Agents to Treat Autoinflammatory Diseases [PDF]

, 2017
In recent years, innovative treatment for patients with autoimmune and autoinflammatory diseases has advanced in concert with our increased understanding of molecular and clinical immunology.
Ostrov, Barbara E.
core   +2 more sources

22q11.2 deletion syndrome [PDF]

, 2015
22q11.2 deletion syndrome (22q11.2DS) is the most common chromosomal microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic recombination events occurring in approximately 1 in every 1,000 fetuses. The first description in
Bassett, Anne S., Emanuel, Beverly S., Marino, Bruno, McDonald-McGinn, Donna M., Morrow, Bernice E., Philip, Nicole, Scambler, Peter J., Sullivan, Kathleen E., Swillen, Ann, Vermeesch, Joris R., Vorstman, Jacob A. S., Zackai, Elaine H.   +11 more
core   +1 more source

Increased adaptive immune responses and proper feedback regulation protect against clinical dengue [PDF]

Science Translational Medicine, American Association for the Advancement of Science, 2017, 9 (405), pp.eaal5088, 2017
Dengue is the most prevalent arthropod-borne viral disease. Clinical symptoms of dengue virus (DENV) infection range from classical mild dengue fever to severe, life-threatening dengue shock syndrome. However, most DENV infections cause few or no symptoms.
arxiv   +1 more source