Results 51 to 60 of about 125,515 (325)

Association of Elevated Serum S100A8/A9 Levels and Cognitive Impairment in Patients With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective Cognitive impairment (CI) is common in patients with systemic lupus erythematosus (SLE). Despite its prevalence, the immune mechanisms are not well understood. We previously reported elevated serum levels of S100A8/A9 and matrix metalloproteinase 9 (MMP‐9) in patients with SLE and CI.
Carolina Muñoz‐Grajales   +18 more
wiley   +1 more source

Evaluation of Humoral Immune Function in Patients with Chronic Idiopathic Thrombocytopenic Purpura

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2013
Coincidence of autoimmune diseases such as immune thrombocytopenic purpura (ITP) with  immunodeficiencies has  been  reported  previously in  patients  who  suffered  from primary antibody deficiency (PAD). But there is no original study on immunological
Mohammad Saeid Rahiminejad   +15 more
doaj  

MHC Class II Deficiency with Normal CD4+ T Cell Counts: A Case Report

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
Major histocompatibility complex (MHC) class II deficiency is a rare primary immunodeficiency disorder (PID) with less than 200 cases worldwide. Here, we report an 8 month–old girl with MHC class II deficiency with a novel homozygous mutation in RFXANK ...
Farhad Abolnezhadian   +2 more
doaj   +1 more source

Transfusion-related acute lung injury associated to intravenous immunoglobulin infusion in a pediatric patient

open access: yesEinstein (São Paulo), 2020
Case report of a patient with an immunodeficiency who demands regular replacement of intravenous immunoglobulin. She presented an episode of transfusion-related acute lung injury shortly after using an immunoglobulin product different than the one she ...
José Roberto Mendes Pegler   +3 more
doaj   +2 more sources

Interleukin-7 and immunologic failure despite treatment with highly active antiretroviral therapy in children perinatally infected with HIV-1.

open access: yesJournal of Acquired Immune Deficiency Syndromes, 2003
Baseline interleukin-7 (IL-7) level has been proposed as a predictor of immunologic response to antiviral therapy, and the use of exogenous IL-7 has been suggested in the treatment of HIV-infected patients.
E. Chiappini   +3 more
semanticscholar   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Psychiatric Aspects of Primary Immunodeficiency Diseases: The Parental Study

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2013
Primary immunodeficiency diseases (PID) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. This study was designed to find out the most important origins and aspects of stressor in parents
Hassan Abolhassani   +9 more
doaj  

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras   +19 more
wiley   +1 more source

Primary immunodeficiency diseases in lung disease: warning signs, diagnosis and management

open access: yesRespiratory Research, 2018
Background Pulmonary complications are common in primary immunodeficiency diseases (PID) and contribute to morbidity and mortality in these patients. However, their varied presentation and a general lack of awareness of PID in this setting make early ...
Pere Soler-Palacín   +6 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

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