Strabismic syndromes and syndromic strabismus - a brief review [PDF]
Strabismus can be found in association with congenital heart diseases, for examples, in velocardiofacial (DiGeorge) syndrome, Down syndrome, mild dysmorphic features, in CHARGE association, Turner syndrome, Ullrich-Turner syndrome, cardiofaciocutaneous syndrome.1-4 Some types of strabismus is heritable (e.g.
arxiv
Modeling COVID-19 vaccine-induced immunological memory development and its links to antibody level and infectiousness [PDF]
COVID-19 vaccines have proven to be effective against SARS-CoV-2 infection. However, the dynamics of vaccine-induced immunological memory development and neutralizing antibodies generation are not fully understood, limiting vaccine development and vaccination regimen determination. Herein, we constructed a mathematical model to characterize the vaccine-
arxiv
Baseline interleukin-7 (IL-7) level has been proposed as a predictor of immunologic response to antiviral therapy, and the use of exogenous IL-7 has been suggested in the treatment of HIV-infected patients.
E. Chiappini+3 more
semanticscholar +1 more source
Modelling Immunological Memory [PDF]
Accurate immunological models offer the possibility of performing highthroughput experiments in silico that can predict, or at least suggest, in vivo phenomena. In this chapter, we compare various models of immunological memory. We first validate an experimental immunological simulator, developed by the authors, by simulating several theories of ...
arxiv
A statistical mechanics approach to autopoietic immune networks [PDF]
The aim of this work is to try to bridge over theoretical immunology and disordered statistical mechanics. Our long term hope is to contribute to the development of a quantitative theoretical immunology from which practical applications may stem. In order to make theoretical immunology appealing to the statistical physicist audience we are going to ...
arxiv +1 more source
Immunological recognition by artificial neural networks [PDF]
The binding affinity between the T-cell receptors (TCRs) and antigenic peptides mainly determines immunological recognition. It is not a trivial task that T cells identify the digital sequences of peptide amino acids by simply relying on the integrated binding affinity between TCRs and antigenic peptides. To address this problem, we examine whether the
arxiv +1 more source
When few survive to tell the tale: thymus and gonad as auditioning organs: historical overview [PDF]
Unlike other organs, the thymus and gonads generate non-uniform cell populations, many members of which perish, and a few survive. While it is recognized that thymic cells are 'audited' to optimize an organism's immune repertoire, whether gametogenesis could be orchestrated similarly to favour high quality gametes is uncertain.
arxiv
Human and computational models of atopic dermatitis:A review and perspectives by an expert panel of the International Eczema Council [PDF]
Atopic dermatitis (AD) is a prevalent disease worldwide and is associated with systemic comorbidities representing a significant burden on patients, their families, and society. Therapeutic options for AD remain limited, in part because of a lack of well-
Bieber, Thomas+15 more
core +4 more sources
Research opportunities on immunocompetence in space [PDF]
The most significant of the available data on the effects of space flight on immunocompetences and the potential operational and clinical significance of reported changes are as follows: (1) reduced postflight blastogenic response of peripheral ...
Beisel, W. R., Talbot, J. M.
core +1 more source
Evaluation of hearing and cochlear function by audiometric testing in patients with hyperemesis gravidarum [PDF]
INTRODUCTION: The aim of this study was to investigate cochlear functions in patients with hyperemesis gravidarum (HG).METHODS: Twenty-nine HG patients (58 ears) and 31 healthy control subjects (62 ears) were included.
Demirtas, Ömer+5 more
core +2 more sources