Results 121 to 130 of about 412,483 (262)

Distinct treatment response trajectories to allergen immunotherapy in allergic asthma and rhinitis: Insights from a multicenter study in routine clinical practice

World Allergy Organization Journal
Background: While allergen-specific immunotherapy (AIT) is recognized as an effective treatment, its efficacy varies widely. However, whether clinical response trajectories to AIT differ among individuals and influence its effectiveness has not been ...
Pingan Zhang, MD, Rundong Qin, PhD, Weixi Zhang, PhD, Yungang Yang, PhD, Huabin Li, PhD, Xiaoyan Dong, PhD, Yong He, PhD, Huiying Wang, PhD, Zhimin Chen, PhD, Liang Chen, PhD, Jinzhun Wu, PhD, Yanmin Bao, PhD, Man Tian, PhD, Guolin Tan, PhD, Jing Ye, PhD, Meiling Jin, PhD, Yi Liang, PhD, Kang Xu, PhD, Lijuan Mao, PhD, Qingqing Lv, PhD, Yi Zhang, PhD, Wanjun Wang, PhD, Jing Li, MD   +22 more
doaj   +1 more source

Human metapneumovirus: Mechanisms and molecular targets used by the virus to avoid the immune system [PDF]

, 2018
Indexación: Scopus.This work was supported by Comisión Nacional de Investigación Científica y Tecnolígica (CONICYT) N◦21151028 and FONDECYT (N◦1070352 and N◦1170964) and the Millennium Institute on Immunology and Immunotherapy (P09/016-F).Human ...
Benavente, F.M., Bueno, S.M., Gonzalez, P.A., Gálvez, N.M.S., Kalergis, A.M., Lay, M.K., Pizarro-Ortega, M.S., Riedel, C., Soto, J.A.   +8 more
core   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Cow’s Milk Desensitization in Anaphylactic Patients: A New Personalized-dose Method

Iranian Journal of Allergy, Asthma and Immunology, 2017
Cow’s milk allergy (CMA) is the most frequent food allergy in children and oral immunotherapy (OIT) is a promising approach for treatment of patients.
Delara Babaie, Mohammad Nabavi, Saba Arshi, Mehrnaz Mesdaghi, Zahra Chavoshzadeh, Mohammad Hasan Bemanian, Mitra Tafakori, Mehrdad Amirmoini, Hosein Esmailzadeh, Rasoul Molatefi, Mahsa Rekabi, Nadieh Akbarpour, Farimah Masoumi, Morteza Fallahpour   +13 more
doaj  

Modulation of c-Jun NH2-Terminal (JNK) by Cholinergic Autoantibodies from Patients with Sjögren’s Syndrome [PDF]

, 2011
Background: We wanted to determine (via an immunopharmacological approach) whether the c-Jun NH2 terminal kinase (JNK) cascade is phosphorylated in the submandibular gland by carbachol and cholinergic autoantibodies (IgG) present in the sera of patients ...
Borda, Enri Santiago, Passafaro, Daniela, Reina, Silvia, Sterin Borda, Leonor   +3 more
core   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Use of Immunotherapy in the Treatment of Peanut Allergies in the Pediatric Population [PDF]

, 2015
Peanut allergies are a serious issue that must be monitored and treated effectively to avoid severe adverse effects and death. In the last decade, their incidence has increased significantly, due to indeterminate factors.
Rauscher, Bethany
core  

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Localized Seminal Plasma Hypersensitivity: Patients’ Reactivity To Seminal Plasma Proteins And Immunological Responses To Desensitization [PDF]

, 2010
Debabrata Ghosh, J.A. Bernstein
openalex   +1 more source