Results 131 to 140 of about 55,587 (208)

Antiresorptive therapy influence on peri‐implant diseases: Clinical implications and osteoimmunological perspectives

open access: yesPeriodontology 2000, EarlyView.
Abstract Background/Aim Antiresorptive therapy represents a cornerstone in the management of osteoporosis and cancer‐related bone disease through suppression of osteoclast‐mediated bone resorption. As implant therapy becomes more common in aging populations, clinicians increasingly encounter patients receiving these medications, thus making their ...
Emilio A. Cafferata   +2 more
wiley   +1 more source

Breakthrough Hemolysis in Paroxysmal Nocturnal Hemoglobinuria: Mechanistic Insights and Management Strategies

open access: yesTransfusion, EarlyView.
Abstract Background Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal hematopoietic stem cell disorder caused by somatic mutations in the PIGA gene, resulting in loss of glycosylphosphatidylinositol (GPI)‐anchored proteins, including the complement regulatory proteins, CD55 and CD59.
Ganesh Raman   +4 more
wiley   +1 more source

Characterisation of Allergen Profiles in Commercial Egg Products to Inform Oral Immunotherapy Strategies in Egg Allergy

open access: yes
Clinical &Experimental Allergy, EarlyView.
Elecia B. Johnston   +10 more
wiley   +1 more source

Study on the cognitive effects of eye movement desensitization and reprocessing: proposed active mechanisms

open access: yesFrontiers in Computational Neuroscience
IntroductionPost-traumatic stress disorder (PTSD) is characterized by intrusive memories and an impaired resilience framework, which often leads to chronic psychological distress.
Tammy Soliman   +2 more
doaj   +1 more source

Bioassays in Allergy: Technical Characteristics, Limitations, and Pathways to Clinical Implementation—An EAACI Position Paper

open access: yesClinical and Translational Allergy, Volume 16, Issue 10, October 2026.
ABSTRACT Bioassays offer functional readouts of immune responses through specific biomarkers, providing mechanistic insight beyond conventional serology. By capturing cellular activation, tissue‐level changes, and molecular signaling, they hold promise for refining allergy diagnosis, risk stratification, and treatment monitoring, contributing to ...
Cagatay Karaaslan   +13 more
wiley   +1 more source

From a 1:4096 Baseline to 1:128 on the Day of Transplantation: Challenging the Titer Barrier in ABO-Incompatible Kidney Transplantation

open access: yesCase Reports in Medicine
ABO-incompatible (ABOi) kidney transplantation protocols universally mandate reducing circulating isoagglutinin titers to ≤ 1:32 on the day of surgery (Day 0) to prevent hyperacute rejection, rendering Day 0 titers ≥ 1:64 a widely accepted ...
Wipada Songwattana   +13 more
doaj   +1 more source

Adverse Reactions Identified after Approval of Novel Medicines: Analysis of 339 New Molecular Entities and Therapeutic Biologics

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1120-1128, October 2026.
Postmarketing safety surveillance data identify safety issues not identified in preapproval clinical trials. We describe the frequency of new safety issues overall and by labeling section and the relationship of the most commonly added safety issues with the cumulative number of prescriptions dispensed via retail pharmacies.
Ellen Pinnow   +14 more
wiley   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

open access: yesAllergy, Volume 81, Issue 10, Page 3439-3452, October 2026.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque   +5 more
wiley   +1 more source

Oral hyposensitization to nickel allergy: preliminary clinical results

open access: yes, 1995
Fifty-one patients presenting a dermatological allergy (erythema, urticaria, angioedema, contact dermatitis) to nickel were treated over 3 years with oral doses of 0.1 ng nickel sulfate per day, following a low-nickel diet.
Pellegrino, Stefano   +3 more
core  

Emerging Paediatric Uses of Dupilumab Beyond Approvals

open access: yesClinical &Experimental Allergy, Volume 56, Issue 10, Page 1162-1176, October 2026.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy