Results 141 to 150 of about 412,483 (262)
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth Cohort
This study investigates whether partial colostrum feeding (PCF) due to formula supplements in the first 3 days increases the risk of food allergy beyond cow's milk. PCF infants showed increased risk of peanut allergy and multiple food allergies compared to exclusively colostrum‐fed (ECF) infants.
Maheshwar Bhasin +11 more
wiley +1 more source
Examining Atopic Dermatitis Through the One Health Concept Lens
ABSTRACT This paper explores the application of the One Health framework to atopic dermatitis (AD), a complex, chronic skin disease, emphasizing interdisciplinary approaches to prevention and management. One Health integrates human, animal, environmental, and plant health, addressing challenges such as antimicrobial resistance, infectious diseases, and
Dijana Minić‐Pantić +10 more
wiley +1 more source
IgH repertoire sequencing of a large atopic dermatitis cohort reveal reduced IgE somatic hypermutation and increased IgE diversity associated with food allergen sensitization. Presence of a dog during the first year of life is associated with increased IgE somatic hypermutation, possibly countering the effect of food sensitization.
Kirandeep K. Gill +18 more
wiley +1 more source
Management of Highly Sensitized Patients in Renal Transplantation: Prospective Single-Center Study
Background and objectives: In kidney transplantation, immunologic risk assessment was performed through pretransplant measurement of human leukocyte antigen, donor-specific antibodies.
Herish Othman Abdulrahman +1 more
doaj +1 more source
LAG‐3+ regulatory T cells suppress the effector but not the proliferative response of naïve cognate antigen‐specific CD4+ T cells in vivo. The suppressed T cells display upregulation of immune checkpoints and downregulation of pro‐inflammatory pathways with enhanced TCR signaling and reduced oxidative metabolism.
Avijit Dutta +7 more
wiley +1 more source
The Development of Hypersensitivity Reactions in the Pediatric Population: A Review [PDF]
Over the past several years, pediatric allergies have come to the forefront of many studies. Reports of immune-mediated hypersensitivity in younger patients have grown and led to an interest researching the causes of pediatric hypersensitivities.
Burns, Heather
core +1 more source
Insights Into circRNA‐Mediated Lipid Metabolism in Cancer Progression
ABSTRACT Lipid metabolism reprogramming is one of the most prominent characteristics of cancer, but it is still unclear which regulatory pathways underlie this process in cancer cells. Circular RNAs (circRNAs) represent a novel category of non‐coding RNAs with multifaceted regulatory functions. While the biological roles of circRNAs in cancer have been
Zhiwei Miao +4 more
wiley +1 more source
ImportancePreformed donor-specific antibodies (pre-DSAs) are a significant immunologic barrier in solid organ transplantation (SOT), yet their association with post-transplant outcomes lacks consensus, limiting standardized clinical management ...
Zhong-yu Kang +4 more
doaj +1 more source

