Results 11 to 20 of about 238,438 (304)

Consensus of Chinese Experts on the Diagnosis and Treatment of Type Ⅰ Interferonopathy

罕见病研究
Type Ⅰ interferonopathy is an autoinflammatory disease that affects multiple systems, with a high disability and mortality rate. It profoundly impacts the quality of life of patients and poses a considerable burden on their families and society.
Chinese Alliance of Pediatric Rheumatic & Immunologic Diseases, Chinese Pharmacists Association Rare Diseases Medication Working Committee   +1 more
doaj   +2 more sources

Acceleration of Precision Medicine in Pediatric Rheumatic and Immunologic Diseases

Xiehe Yixue Zazhi, 2023
Rheumatic and immunologic diseases in children may involve multiple genes and interactions between genetic and environmental factors. There are no validated biomarkers that are predictive of treatment response.
MA Mingsheng, SONG Hongmei
doaj   +2 more sources

BCG turns 100: its nontraditional uses against viruses, cancer, and immunologic diseases. [PDF]

J Clin Invest, 2021
First administered to a human subject as a tuberculosis (TB) vaccine on July 18, 1921, Bacillus Calmette-Guérin (BCG) has a long history of use for the prevention of TB and later the immunotherapy of bladder cancer.
Singh AK, Netea MG, Bishai WR.
europepmc   +2 more sources

Regulatory dendritic cells for immunotherapy in immunologic diseases. [PDF]

Front Immunol, 2014
We recognize well the abilities of dendritic cells to activate effector T cell responses to an array of antigens and we think of these cells in this context as pre-eminent antigen presenting cells, but dendritic cells are also critical to the induction ...
Gordon JR, Ma Y, Churchman L, Gordon SA, Dawicki W.   +4 more
europepmc   +2 more sources

Quality of life in patients with allergic and immunologic skin diseases: in the eye of the beholder [PDF]

, 2021
Allergic and immunologic skin diseases negatively impact the quality of life (QoL) of affected patients with detrimental consequences. Nonetheless, in everyday clinical practice the evaluation of QoL is often overlooked.
Nettis, Eustachio, Angileri, Luisa, Tarrini, Daniele, Napolitano, Maddalena, Schettini, Natale, Gallo, Rosella, Fabrizio Guarneri, Guarneri, Fabrizio, Adriana Di Guida, Alessia Gatta, Di Agosta, Ester, Francesca Ambrogio, Luca Stingeni, Diego Peroni, Lamacchia, Donatella, Passante, Maria, Luisa Angileri, Bonamonte, Domenico, Di Leo, Elisabetta, Silvia Mariel Ferrucci, Federica Belluzzo, Fassio, Filippo, Fantò, Marta, Lombardo, Carla, Cristina Quecchia, Tramontana, Marta, Brancaccio, Raffaele, Caterina Foti, Ambrogio, Francesca, Rosella Gallo, Katharina Hansel, Eustachio Nettis, Di Guida, Adriana, Raffaele Brancaccio, Paravisi, Andrea, Baiardini, Ilaria, Detoraki, Aikaterini, Donatella Lamacchia, Marta Tramontana, Ferrucci, Silvia Mariel, Quecchia, Cristina, Paolo Custurone, Belluzzo, Federica, Spadaro, Giuseppe, Gatta, Alessia, Giuseppe Spadaro, Hansel, Katharina, Monica Corazza, Marta Fantò, Andrea Paravisi, Alessandro Pannofino, Corazza, Monica, Filippo Fassio, Patruno, Cataldo, Minciullo, Paola Lucia, Rossi, Oliviero, Parente, Roberta, Laura Bonzano, Guidolin, Lucia, Elettra Antonelli, Ilaria Baiardini, Paola Lucia Minciullo, Stingeni, Luca, Aurora De Marco, Carla Lombardo, Cataldo Patruno, Custurone, Paolo, Natale Schettini, Pannofino, Alessandro, Oliviero Rossi, Maria Passante, De Marco, Aurora, Roberta Parente, Bonzano, Laura, Lorenzo Salvati, Salvati, Lorenzo, Maddalena Napolitano, Domenico Bonamonte, Peroni, Diego, Aikaterini Detoraki, Lucia Guidolin, Daniele Tarrini, Elisabetta Di Leo, Antonelli, Elettra, Foti, Caterina, Ester Di Agosta   +85 more
core   +2 more sources

Regulation of splenic monocyte homeostasis and function by gut microbial products

iScience, 2021
Summary: Splenic Ly6Chigh monocytes are innate immune cells involved in the regulation of central nervous system-related diseases. Recent studies have reported the shaping of peripheral immune responses by the gut microbiome via mostly unexplored ...
Panayota Kolypetri, Shirong Liu, Laura M. Cox, Mai Fujiwara, Radhika Raheja, Dvora Ghitza, Anya Song, Dominique Daatselaar, Valerie Willocq, Howard L. Weiner   +9 more
doaj   +1 more source

The potential roles of type I interferon activated neutrophils and neutrophil extracellular traps (NETs) in the pathogenesis of primary Sjögren’s syndrome

Arthritis Research & Therapy, 2022
Objective Neutrophils and aberrant NETosis have been implicated in the pathogenesis of diverse autoimmune diseases; however, their roles in primary Sjögren’s syndrome (pSS) remain unclear.
Yu Peng, Xunyao Wu, Shulan Zhang, Chuiwen Deng, Lidan Zhao, Mu Wang, Qingjun Wu, Huaxia Yang, Jiaxin Zhou, Linyi Peng, Xuan Luo, Yingying Chen, Anqi Wang, Qiufeng Xiao, Wen Zhang, Yan Zhao, Xiaofeng Zeng, Yunyun Fei   +17 more
doaj   +1 more source

Real-World Clinical Characteristics, Management, and Outcomes of 44 Paediatric Patients with Hypopigmented Mycosis Fungoides

Acta Dermato-Venereologica, 2023
Hypopigmented mycosis fungoides is a rare form of mycosis fungoides that is characterized by achromic lesions, early onset of disease, a predilection for darker skinned populations, and a predominance of CD8+ T cells.
Zhong-Hui Hu, Lu Lu, Jin-Di Feng, Hong-Bin Song, Shi-Yu Zhang, Lu Yang, Tao Wang, Yue-Hua Liu   +7 more
doaj   +1 more source

The immunology of Parkinson’s disease

Seminars in Immunopathology, 2022
AbstractParkinson’s disease (PD) is the second most common neurodegenerative disorder which affects 6.1 million people worldwide. The neuropathological hallmarks include the loss of dopaminergic neurons in the substantia nigra, the presence of Lewy bodies and Lewy neurites caused by α-synuclein aggregation, and neuroinflammation in the brain.
Biqing Zhu, Dominic Yin, Hongyu Zhao, Le Zhang   +3 more
openaire   +2 more sources

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis [PDF]

, 2016
Atopic dermatitis (AD) is a complex skin disease frequently associated with other diseases of the atopic diathesis. Recent evidence supports the concept that AD can also recognize other comorbidities, such as chronic inflammatory bowel or cardiovascular ...
Werfel, T., Guttman-Yassky, E., Werfel, Thomas, Hoetzenecker, W., Bieber, Thomas, Knol, E., Wollenberg, Andreas, Schmid-Grendelmeier, Peter, Biedermann, Tilo, Gilles, Stefanie, Akdis, Cezmi A, Gilles, S., Akdis, Cezmi A., Guttman-Yassky, Emma, Bieber, T., Hoetzenecker, Wolfram, Wollenberg, A., Simon, H.U., Allam, Jean-Pierre, Allam, J.P., Lauener, R., Traidl-Hoffmann, C., Eyerich, K., Biedermann, T., Lauener, Roger, Traidl-Hoffmann, Claudia, Akdis, C.A., Simon, Hans-Uwe, Knol, Edward, Schmid-Grendelmeier, P., Eyerich, Kilian   +30 more
core   +2 more sources