Results 11 to 20 of about 2,385,812 (262)

Consensus of Chinese Experts on the Diagnosis and Treatment of Type Ⅰ Interferonopathy

罕见病研究
Type Ⅰ interferonopathy is an autoinflammatory disease that affects multiple systems, with a high disability and mortality rate. It profoundly impacts the quality of life of patients and poses a considerable burden on their families and society.
Chinese Alliance of Pediatric Rheumatic & Immunologic Diseases, Chinese Pharmacists Association Rare Diseases Medication Working Committee   +1 more
doaj   +2 more sources

Acceleration of Precision Medicine in Pediatric Rheumatic and Immunologic Diseases

Xiehe Yixue Zazhi, 2023
Rheumatic and immunologic diseases in children may involve multiple genes and interactions between genetic and environmental factors. There are no validated biomarkers that are predictive of treatment response.
MA Mingsheng, SONG Hongmei
doaj   +2 more sources

BCG turns 100: its nontraditional uses against viruses, cancer, and immunologic diseases. [PDF]

J Clin Invest, 2021
First administered to a human subject as a tuberculosis (TB) vaccine on July 18, 1921, Bacillus Calmette-Guérin (BCG) has a long history of use for the prevention of TB and later the immunotherapy of bladder cancer.
Singh AK, Netea MG, Bishai WR.
europepmc   +3 more sources

Quality of life in patients with allergic and immunologic skin diseases: in the eye of the beholder [PDF]

, 2021
Allergic and immunologic skin diseases negatively impact the quality of life (QoL) of affected patients with detrimental consequences. Nonetheless, in everyday clinical practice the evaluation of QoL is often overlooked.
Passante M, Custurone P, Foti C, Spadaro G, Belluzzo F, Salvati L, Rossi O, Ambrogio F, Ferrucci SM, Stingeni L, Tarrini D, Di Guida A, Nettis E, Tramontana M, Napolitano M, Parente R, Fassio F, Baiardini I, Di Leo E, Paravisi A, Bonzano L, Fantò M, Patruno C, Antonelli E, Gallo R, Guarneri F, Detoraki A, Lamacchia D, Guidolin L, Minciullo PL, De Marco A, Angileri L, Lombardo C, Gatta A, Pannofino A, Schettini N, Brancaccio R, Di Agosta E, Hansel K, Peroni D, Corazza M, Bonamonte D, Quecchia C   +42 more
core   +2 more sources

Real-World Clinical Characteristics, Management, and Outcomes of 44 Paediatric Patients with Hypopigmented Mycosis Fungoides

Acta Dermato-Venereologica, 2023
Hypopigmented mycosis fungoides is a rare form of mycosis fungoides that is characterized by achromic lesions, early onset of disease, a predilection for darker skinned populations, and a predominance of CD8+ T cells.
Zhong-Hui Hu, Lu Lu, Jin-Di Feng, Hong-Bin Song, Shi-Yu Zhang, Lu Yang, Tao Wang, Yue-Hua Liu   +7 more
doaj   +1 more source

Regulation of splenic monocyte homeostasis and function by gut microbial products

iScience, 2021
Summary: Splenic Ly6Chigh monocytes are innate immune cells involved in the regulation of central nervous system-related diseases. Recent studies have reported the shaping of peripheral immune responses by the gut microbiome via mostly unexplored ...
Panayota Kolypetri, Shirong Liu, Laura M. Cox, Mai Fujiwara, Radhika Raheja, Dvora Ghitza, Anya Song, Dominique Daatselaar, Valerie Willocq, Howard L. Weiner   +9 more
doaj   +1 more source

The potential roles of type I interferon activated neutrophils and neutrophil extracellular traps (NETs) in the pathogenesis of primary Sjögren’s syndrome

Arthritis Research & Therapy, 2022
Objective Neutrophils and aberrant NETosis have been implicated in the pathogenesis of diverse autoimmune diseases; however, their roles in primary Sjögren’s syndrome (pSS) remain unclear.
Yu Peng, Xunyao Wu, Shulan Zhang, Chuiwen Deng, Lidan Zhao, Mu Wang, Qingjun Wu, Huaxia Yang, Jiaxin Zhou, Linyi Peng, Xuan Luo, Yingying Chen, Anqi Wang, Qiufeng Xiao, Wen Zhang, Yan Zhao, Xiaofeng Zeng, Yunyun Fei   +17 more
doaj   +1 more source

Kinetoplastids: related protozoan pathogens, different diseases. [PDF]

, 2008
Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Gürtler, Ricardo E, Tarleton, Rick, Reed, Steve, Stuart, Ken, Guertler, Ricardo E., Fairlamb, Alan; id_orcid, Ken Stuart, Steve Reed, Brun, Reto, McKerrow, Jim, Jim McKerrow, Fairlamb, Alan, Ricardo E. Gürtler, Alan Fairlamb, Rick Tarleton, Reto Brun, Simon Croft, Croft, Simon   +17 more
core   +1 more source

RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression

Cell Reports, 2016
Interleukin-17 (IL-17)-producing helper T cells (Th17 cells) play an important role in autoimmune diseases. However, not all Th17 cells induce tissue inflammation or autoimmunity. Th17 cells require IL-23 receptor (IL-23R) signaling to become pathogenic.
Gerd Meyer zu Horste, Chuan Wu, Chao Wang, Le Cong, Mathias Pawlak, Youjin Lee, Wassim Elyaman, Sheng Xiao, Aviv Regev, Vijay K. Kuchroo   +9 more
doaj   +1 more source

Uveitis and hypereosinophilia associated with dupilumab in an atopic dermatitis patient

Journal of Dermatological Treatment, 2023
Uveitis is a rare adverse event of dupilumab, that typically affects both eyes and often leads to discontinuation of therapy. In this article, we report a case of a 28-year-old female with atopic dermatitis who developed new-onset iridocyclitis, a form ...
Shiyu Zhang, Lu Lu, Jindi Feng, Zhonghui Hu, Hongbin Song, Lu Yang, Yuehua Liu, Di Chen, Tao Wang   +8 more
doaj   +1 more source