Results 31 to 40 of about 312,025 (347)

Current status of intestinal transplantation in children [PDF]

, 1998
Purpose: A clinical trial of intestinal transplantation (Itx) under tacrolimus and prednisone immunosuppression was initiated in June 1990 in children with irreversible intestinal failure and who were dependent on total parenteral nutrition (TPN ...
Asfar, Billingham, Casavilla, Deltz, Edward M Barksdale, Fontes, Furukawa, Garau, Goulet, Grant, Grant, Grant, Green, Hiro Furukawa, Iwaki, Javier Bueno, John J Fung, Jorge Reyes, Kareem Abu-Elmagd, Kashiwagi, Langnas, Lee, Lillehei, Manez, Margreiter, McAlister, Mike Green, Monchik, Murase, Murase, Porter, Putnam, Randhawa, Rao, Reyes, Reyes, Reyes, Samuel Kocoshis, Satoru Todo, Sharon Strom, Sigurdsson, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Takaya, Thomas E Starzl, Todo, Tzakis, White, William Irish   +52 more
core   +1 more source

The natural course of hereditary angioedema in a Chinese cohort

Orphanet Journal of Rare Diseases, 2020
Background Hereditary angioedema (HAE) is a rare disease with potential life-threatening risks. To study the natural course of HAE under therapy-free conditions throughout patient life is essential for practitioners and patients to avoid possible risk ...
Yang Cao, Shuang Liu, Yuxiang Zhi
doaj   +1 more source

Infections Complicating Orthotopic Liver Transplantation: A Study Emphasizing Graft-Related Septicemia [PDF]

, 1976
In 93 recipients of 102 orthotopic liver homografts, the incidence of bacteremia or fungemia exceeded 70%. The graft itself was usually an entry site for systemic infection after both immunologic and nonimmunologic parenchymal injury, especially if there
Hansbrough, JF, Hoelscher, M, Porter, KA, Putnam, CW, Schröter, GPJ, Starzl, TE   +5 more
core   +1 more source

Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease

Frontiers in Immunology, 2022
BackgroundThe IgG4-related disease (IgG4-RD) is an immune-mediated disorder with fibrotic manifestations. However, the transcriptional profiles of immune cell subsets at single-cell level are unknown. Herein, single-cell sequencing was used to assess the
Xunyao Wu, Xunyao Wu, Yu Peng, Jieqiong Li, Panpan Zhang, Zheng Liu, Hui Lu, Linyi Peng, Jiaxin Zhou, Yunyun Fei, Xiaofeng Zeng, Yan Zhao, Wen Zhang   +12 more
doaj   +1 more source

Cell therapy in Sjögren's syndrome: opportunities and challenges

Expert Reviews in Molecular Medicine
Sjögren's syndrome (SS) is a chronic autoimmune disease caused by immune system disorders. The main clinical manifestations of SS are dry mouth and eyes caused by the destruction of exocrine glands, such as the salivary and lacrimal glands, and systemic ...
Yangyang Lu, Rongjing Shi, Wenqin He, Qi An, Jingwen Zhao, Xinnan Gao, Baiyan Zhang, Liyun Zhang, Ke Xu, Dan Ma   +9 more
doaj   +1 more source

Eosinophilic granulomatosis with polyangiitis (EGPA) and PRES: a case-based review of literature in ANCA-associated vasculitides [PDF]

, 2015
Eosinophilic granulomatosis with polyangiitis (EGPA) is a small-sized vessel systemic necrotizing vasculitis and belongs to the family of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides.
Barilaro, Giuseppe, Granata, Massimo, Marra, ALESSANDRO MARIA, Villella, Valeria   +3 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Enzyme replacement therapies: What is the best option? [PDF]

, 2018
Despite many beneficial outcomes of the conventional enzyme replacement therapy (ERT), several limitations such as the high-cost of the treatment and various inadvertent side effects including the occurrence of an immunological response against the ...
Barar, Jaleh, Khiavi, Mostafa Akbarzadeh, Mousavi, Rahimeh, Rafi, Mohammad, Safary, Azam   +4 more
core   +2 more sources

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the MK2 Inhibitor ATI-450 in Healthy Subjects: A Placebo-Controlled, Randomized Phase 1 Study

Clinical Pharmacology: Advances and Applications, 2021
David Gordon,1 Edward T Hellriegel,1 Heidi Rath Hope,2 David Burt,1 Joseph B Monahan2 1Research and Development, Aclaris Therapeutics, Inc., Wayne, PA, USA; 2Research and Development, Aclaris Therapeutics, Inc., and Confluence Discovery Technologies, Inc.
Gordon D, Hellriegel ET, Hope HR, Burt D, Monahan JB   +4 more
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