Results 31 to 40 of about 2,385,812 (262)

Immunofuorescence in Various Skin Diseases

, 2023
Immunofluorescence (IF) is a technique widely used both to investigate pathophysiology and to help in the accurate diagnosis of various cutaneous disorders, especially bullous diseases and connective tissue diseases.
Feliciani C., Massa A., Lotti T. M., Satolli F.   +3 more
core   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

The natural course of hereditary angioedema in a Chinese cohort

Orphanet Journal of Rare Diseases, 2020
Background Hereditary angioedema (HAE) is a rare disease with potential life-threatening risks. To study the natural course of HAE under therapy-free conditions throughout patient life is essential for practitioners and patients to avoid possible risk ...
Yang Cao, Shuang Liu, Yuxiang Zhi
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Single-Cell Sequencing of Immune Cell Heterogeneity in IgG4-Related Disease

Frontiers in Immunology, 2022
BackgroundThe IgG4-related disease (IgG4-RD) is an immune-mediated disorder with fibrotic manifestations. However, the transcriptional profiles of immune cell subsets at single-cell level are unknown. Herein, single-cell sequencing was used to assess the
Xunyao Wu, Xunyao Wu, Yu Peng, Jieqiong Li, Panpan Zhang, Zheng Liu, Hui Lu, Linyi Peng, Jiaxin Zhou, Yunyun Fei, Xiaofeng Zeng, Yan Zhao, Wen Zhang   +12 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Immunologic manifestations of autophagy

, 2015
The broad immunologic roles of autophagy span innate and adaptive immunity and are often manifested in inflammatory diseases. The immune effects of autophagy partially overlap with its roles in metabolism and cytoplasmic quality control but typically ...
Vojo Deretic, Deretic, Vojo, Pope Moseley, Michael Mandell, Santosh Chauhan, Chauhan, Santosh, Tomonori Kimura, Graham Timmins, Kimura, Tomonori, Mandell, Michael, Timmins, Graham, Moseley, Pope   +11 more
core   +1 more source

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis [PDF]

, 2016
Atopic dermatitis (AD) is a complex skin disease frequently associated with other diseases of the atopic diathesis. Recent evidence supports the concept that AD can also recognize other comorbidities, such as chronic inflammatory bowel or cardiovascular ...
Werfel, T., Guttman-Yassky, E., Werfel, Thomas, Hoetzenecker, W., Bieber, Thomas, Knol, E., Wollenberg, Andreas, Schmid-Grendelmeier, Peter, Biedermann, Tilo, Gilles, Stefanie, Akdis, Cezmi A, Gilles, S., Akdis, Cezmi A., Guttman-Yassky, Emma, Bieber, T., Hoetzenecker, Wolfram, Wollenberg, A., Simon, H.U., Allam, Jean-Pierre, Allam, J.P., Lauener, R., Traidl-Hoffmann, C., Eyerich, K., Biedermann, T., Lauener, Roger, Traidl-Hoffmann, Claudia, Akdis, C.A., Simon, Hans-Uwe, Knol, Edward, Schmid-Grendelmeier, P., Eyerich, Kilian   +30 more
core   +3 more sources

Mutation update of SERPING1 related to hereditary angioedema in the Chinese population

Hereditas, 2022
Background Hereditary angioedema (HAE) is a rare disease characterized by recurrent attacks of severe swellings of the skin and submucosa. More than 900 variants of the SERPING1 gene associated with HAE have been identified.
Xue Wang, Shubin Lei, Yingyang Xu, Shuang Liu, Yuxiang Zhi   +4 more
doaj   +1 more source