Results 41 to 50 of about 2,385,812 (262)

Clinical Characteristics and Prognoses of Patients With Systemic Lupus Erythematosus Hospitalized for Pulmonary Infections

Frontiers in Medicine, 2021
Objective: To identify factors associated with mortality in SLE patients who were hospitalized for pulmonary infections (PIs).Methods: This single-center retrospective study analyzed the characteristics and risk factors for mortality in 95 SLE patients ...
Yanli Yang, Yanli Yang, Hui Jiang, Chuhan Wang, Nan Jiang, Chanyuan Wu, Shangzhu Zhang, Wei Jiang, Jinmin Peng, Li Weng, Jiuliang Zhao, Qian Wang, Mengtao Li, Bin Du, Yan Zhao, Xiaofeng Zeng   +15 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Neutrophil Extracellular Traps Promote Aberrant Macrophages Activation in Behçet’s Disease

Frontiers in Immunology, 2021
Neutrophil extracellular traps (NETs) are upregulated and promote thrombosis in Behçet’s disease (BD). However, whether NETs promote autoinflammation in BD remains unclear.
Lu Li, Lu Li, Xin Yu, Jinjing Liu, Zhimian Wang, Chaoran Li, Jing Shi, Luxi Sun, Yi Liu, Fengchun Zhang, Hua Chen, Wenjie Zheng   +11 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A practical guide to recognize allergic and immunologic skin diseases: diagnosis at first sight [PDF]

Allergic and immunologic skin diseases are becoming increasingly common and this requires clinicians to be able to recognize and diagnose them. A joint meeting (GET TOGETHER 2022) of the Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC)
Hansel, Katharina, Di Bartolomeo, Luca, Filon, Francesca Larese, Nettis, Eustachio, Schettini, Natale, Boni, Elisa, Napolitano, Maddalena, Bova, Maria, Cannas, Rossana, Gallo, Rosella, Guarneri, Fabrizio, Di Agosta, Ester, Corazza, Monica, Patruno, Cataldo, Potestio, Luca, Rossi, Oliviero, Buonomo, Alessandro, Passante, Maria, Bonamonte, Domenico, De Pasquale, Tiziana, Stingeni, Luca, Cataudella, Edoardo, Marietti, Rossella, Perlato, Margherita, Ferrucci, Silvia, Di Pino, Marina, Mormile, Ilaria, Tramontana, Marta, Angilieri, Luisa, Ambrogio, Francesca, De Marco, Aurora, Magistà, Stefania, Zaza, Ippolita, Gangemi, Sebastiano, Salvati, Lorenzo, Zancanaro, Andrea, Paolino, Donato, Testi, Sergio, Romaldi, Arianna, Trave, Ilaria, Conte, Maria Elisabetta, Foti, Caterina   +41 more
core   +1 more source

Protein profiling in systemic sclerosis patients with different pulmonary complications using proteomic antibody microarray

Arthritis Research & Therapy
Background Pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) are leading causes of systemic sclerosis (SSc)-related death. In this study, we aimed to identify biomarkers for detecting SSc pulmonary complications that are mild and ...
Jing Huang, Honglin Zhu, Sijia Liu, Mengtao Li, Yisha Li, Hui Luo, Xiaoxia Zuo   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Clinical characteristics of patients with a family history of psoriasis: an observational epidemiological study in Chinese Han population

Frontiers in Medicine
IntroductionPsoriasis, a chronic inflammatory skin disease, is believed to be influenced by both genetic and environmental factors. Despite this understanding, the clinical epidemiological status of psoriasis patients with a family history of the disease
Lu Cao, Lu Cao, Lingyi Lu, Lingyi Lu, Yingzhe Yu, Yingzhe Yu, Huiying Zhou, Huiying Zhou, Bingjiang Lin, Bingjiang Lin   +9 more
doaj   +1 more source

A Bibliometric Analysis of Melanoma Treated with Vaccinations Research from 2013 to 2023: A Comprehensive Review of the Literature

Vaccines, 2023
Backgrounds: Melanoma is a malignant tumor that originates from melanocytes and is known for its aggressive behavior and high metastatic potential.
Xinyu Wang, Qian-Nan Jia, Mengyin Wu, Mingjuan Liu, Jun Li   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source