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The immunology of coeliac disease
Springer Seminars in Immunopathology, 1990 Whether or not the immune system initiates CD, it can be seen to play a role in the natural history of the disease. Genetic susceptibility to CD has been shown to be linked to the HLA, DQw2 and it appears that other genes within the MHC further contribute to disease susceptibility. The search for other immune response genes that may be linked to CD has
Mantzaris, G, Rosenberg, WM, Jewell, D
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Kinetoplastids: related protozoan pathogens, different diseases. [PDF]
, 2008 Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their
Gürtler, Ricardo E +17 more
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T Cells Immunology in the Immunological Diseases
Journal of Immunology Research, 2014 Immunological diseases, with the morbidity keeping increased, have become a major threat to human mental and physical health. However, the pathogenesis of these diseases is extremely complicated and remains unclear. Recent advances in biology have introduced new technologies to study the underlying mechanisms that contribute to the development of ...
Xiuli Wu +3 more
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RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression
Cell Reports, 2016 Interleukin-17 (IL-17)-producing helper T cells (Th17 cells) play an important role in autoimmune diseases. However, not all Th17 cells induce tissue inflammation or autoimmunity. Th17 cells require IL-23 receptor (IL-23R) signaling to become pathogenic.
Gerd Meyer zu Horste +9 more
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Immunofuorescence in Various Skin Diseases
, 2023 Immunofluorescence (IF) is a technique widely used both to investigate pathophysiology and to help in the accurate diagnosis of various cutaneous disorders, especially bullous diseases and connective tissue diseases.
Feliciani C. +3 more
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Uveitis and hypereosinophilia associated with dupilumab in an atopic dermatitis patient
Journal of Dermatological Treatment, 2023 Uveitis is a rare adverse event of dupilumab, that typically affects both eyes and often leads to discontinuation of therapy. In this article, we report a case of a 28-year-old female with atopic dermatitis who developed new-onset iridocyclitis, a form ...
Shiyu Zhang +8 more
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, 2022 Dehydroepiandrosterone (DHEA) is an adrenal steroid converted to potent androgens. This study aimed to discover the association between serum DHEA levels and immunologic response in people with HIV/AIDS (PLWHA).
Ki Hyun Lee +19 more
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Peripheral B-Cell Immunophenotyping Identifies Heterogeneity in IgG4-Related Disease
Frontiers in Immunology, 2021 ObjectivesTo elucidate heterogeneity of IgG4-related disease (IgG4-RD) based on B cell immunophenotyping.MethodsImmunophenotyping of 4 B-cell subsets in peripheral blood from patients with active IgG4-RD (aIgG4-RD, n=105) was performed using flow ...
Jieqiong Li +17 more
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Alterations of the human gut microbiome in multiple sclerosis
Nature Communications, 2016 The gut microbiome has been implicated in several autoimmune disorders. Here, the authors study the gut microbiome of patients with multiple sclerosis, and find correlations between altered abundance of certain gut microorganisms and changes in ...
Sushrut Jangi +24 more
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Immunology and Immunologic Diseases of the Lung [PDF]
JAMA: The Journal of the American Medical Association, 1989 ABSTRACT Immunology and Immunologic Diseases of the Lung, edited by Ronald P. Daniele, MD, is an important addition to the many books on pulmonary medicine. The explosive growth of knowledge in immunology during the past few decades and the recognition that the lung is a key player in many immunologic disorders justify the assembly of this material as ...
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