Results 41 to 50 of about 42,777 (163)

Immune responses to zoster vaccines

Human Vaccines & Immunotherapeutics, 2019
There are two licensed herpes zoster vaccines. One is a live vaccine (ZVL) based on an attenuated varicella-zoster virus (VZV). The other is a recombinant vaccine (RZV) based on the VZV glycoprotein E (gE) combined with AS01B, a multicomponent adjuvant ...
Myron J Levin, Adriana Weinberg
doaj   +1 more source

Radiation and Local Anti-CD40 Generate an Effective in situ Vaccine in Preclinical Models of Pancreatic Cancer

Frontiers in Immunology, 2018
Radiation therapy induces immunogenic cell death, which can theoretically stimulate T cell priming and induction of tumor-specific memory T cell responses, serving as an in situ vaccine. In practice, this abscopal effect is rarely observed.
Sayeda Yasmin-Karim, Sayeda Yasmin-Karim, Patrick T. Bruck, Michele Moreau, Michele Moreau, Sijumon Kunjachan, Gui Zhen Chen, Rajiv Kumar, Stephanie Grabow, Stephanie Grabow, Stephanie K. Dougan, Stephanie K. Dougan, Wilfred Ngwa, Wilfred Ngwa, Wilfred Ngwa   +14 more
doaj   +1 more source

Immunological Memory in Innate Immunity [PDF]

Journal of Innate Immunity, 2013
‘trained immunity’. Trained immunity provides protection against reinfection in a T-/B-cell-independent manner, with nonspecific potentiation of inflammatory reactions and antimicrobial mechanisms playing a central role in these effects [4] . The current issue of the Journal of Innate Immunity presents a series of studies that shed additional light on ...
Netea, M.G., Netea, M.G.
openaire   +4 more sources

Sequential monitoring of lymphocyte subsets and of T-and-B cell neogenesis indexes to identify time-varying immunologic profiles in relation to graft-versus-host disease and relapse after allogeneic stem cell transplantation. [PDF]

PLoS ONE, 2017
T and B lymphocyte subsets have been not univocally associated to Graft-versus-host disease (GVHD) and relapse of hematological malignancies after stem cell transplantation (SCT).
Cristina Skert, Simone Perucca, Marco Chiarini, Viviana Giustini, Alessandra Sottini, Claudia Ghidini, Stefano Martellos, Federica Cattina, Benedetta Rambaldi, Valeria Cancelli, Michele Malagola, Alessandro Turra, Nicola Polverelli, Simona Bernardi, Luisa Imberti, Domenico Russo   +15 more
doaj   +1 more source

Integrated analysis of humoral and T-cell responses to pneumococcal vaccination in allogeneic hematopoietic stem cell transplant recipients

Frontiers in Medicine
IntroductionAllogeneic hematopoietic stem cell transplant (HSCT) recipients remain highly susceptible to pneumococcal infection despite current vaccination strategies, and the contribution of T-cell–mediated immunity to protection in this population is ...
André Silva-Pinto, André Silva-Pinto, André Silva-Pinto, Ana Isabel Pinto, Ana Isabel Pinto, Pedro Curto, Joana Ribeiro, Joana Ribeiro, Ricardo Pinto, Ricardo Pinto, Juliana Bastos, Juliana Bastos, Lurdes Santos, Lurdes Santos, Joana Tavares, Joana Tavares, Anabela Cordeiro-da-Silva, Anabela Cordeiro-da-Silva   +17 more
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An evaluation of cytokine and cellular immune responses to heterologous prime-boost vaccination with influenza A/H7N7-A/H7N9 inactivated vaccine

Human Vaccines & Immunotherapeutics, 2020
The immunologic mechanisms underlying the improved serologic responses to heterologous prime-boost avian influenza vaccination are unclear. An exploratory analysis of the immune responses following 1 dose of influenza A/H7N9 inactivated vaccine in ...
Hana M El Sahly, George Makedonas, David Corry, Robert L Atmar, Abbie Bellamy, Kaitlyn Cross, Wendy A Keitel   +6 more
doaj   +1 more source

Regulatory T cells in γ irradiation-induced immune suppression. [PDF]

PLoS ONE, 2012
Sublethal total body γ irradiation (TBI) of mammals causes generalized immunosuppression, in part by induction of lymphocyte apoptosis. Here, we provide evidence that a part of this immune suppression may be attributable to dysfunction of immune ...
Hugh I McFarland, Montserrat Puig, Lucja T Grajkowska, Kazuhide Tsuji, Jay P Lee, Karen P Mason, Daniela Verthelyi, Amy S Rosenberg   +7 more
doaj   +1 more source

A dual nature of γδ T cell immune memory responses

eLife
Immune memory was considered for decades an exclusive hallmark of the adaptive immune response. However, recent studies have revealed that innate immune cells can also ‘recall’ information of a primary insult during infection or vaccination and deploy ...
Tsz Kin Suen, Burcu Al, Alice Scarpa, Anca Dorhoi, Mihai G Netea, Katarzyna Placek   +5 more
doaj   +1 more source

Involvement of memory T-cells in the pathophysiology of chronic lymphocytic leukemia

Revista Brasileira de Hematologia e Hemoterapia, 2014
The role of T-cells in the pathogenesis of chronic lymphocytic leukemia has recently gained much attention due to the importance of the constant interaction between neoplastic B-cells with microenvironment substratum and T-cells.
Rodolfo Patussi Correia, Flavia Amoroso Matos e Silva, Nydia Strachman Bacal, Paulo Vidal Campregher, Nelson Hamerschlak, Gustavo P. Amarante-Mendes   +5 more
doaj   +1 more source

Modelling Immunological Memory [PDF]

, 2007
26 pages, In Silico ...
Garret, S, Robbins, M, Walker, J, Wilson, W, Aickelin, U   +4 more
openaire   +4 more sources