Comparison of immunoresponse in PHB, YHB-vaccinee, and immunological background of non-responder.
B型肝炎ウイルスの院内感染予防を目的として医療従事者1,736名を対象に,人血漿由来HBワクチン(PHB vaccine)と遺伝子組替え酵母由来HBワクチン(YHB vaccine)の2種のワクチン接種を行い,その成績を比較した.併せてPHBワクチン接種群の抗体価の推移,および無反応例について細胞性免疫能を検討した.HBs抗体陽転率および獲得抗体価の対比では,PHBワクチン接種群の抗体陽転率は86%に留まったが,獲得抗体価は平均CI 97, (RIA法)であったのに対して,YHBワクチン接種群の陽転率は99%と高率であったが,獲得抗体価は平均CI 39, (RIA法)と低値であった.PHBワクチン接種群203例の抗体価の推移ほ9ヵ月後に平均55%の低下率を示した ...
TAKEUCHI, Naoko +2 more
openaire +2 more sources
DOMS intensity in responders and non-responders.
DOMS intensity in responders and non-responders.
Einat Kodesh (13132997) +4 more
core +1 more source
Eradication of Helicobacter pylori can facilitate immune reconstitution in HIV-1-infected immunological non-responders [PDF]
A significant number of HIV-1 patients experience poor immune reconstitution despite long-term viral suppression with highly active antiretroviral therapy (immunological non-responders). The aims of the present study were to determine whether eradication of Helicobacter pylori could facilitate a better immune reconstitution in these patients.Forty-nine
Magen, Eli +4 more
openaire +2 more sources
Increased early activation of CD56dimCD16dim/- natural killer cells in immunological non-responders correlates with CD4+ T-cell recovery. [PDF]
Abstract Background Natural killer (NK) cells play a critical role in suppressing human immunodeficiency virus-1 (HIV-1) infection, but knowledge on whether and how NK cells affect immune reconstitution in HIV-1-infected individuals who receive antiretroviral therapy (ART) is limited.
Zhang QY +9 more
europepmc +4 more sources
Demographic characteristics of responders and non-responders.
Demographic characteristics of responders and non-responders.
Katja Stahl (4994483) +1 more
core +1 more source
List of abbreviations: AIDS, acquired immunodeficiency syndrome; eGFR, estimated glomerular filtration rate; INR, immunological non-responders; IR, Immunological responders.Severe non AIDS-related events observed during the follow-up (overall results and
Massimo Di Pietro (237801) +12 more
core +1 more source
Implications of accumulation of clonally expanded and senescent CD4+GNLY+ T cells in immunological non-responders of HIV-1 infection. [PDF]
Increased CD4+GNLY+ T cells have been confirmed to be inversely associated with CD4+ T cell count in immunological non-responders (INRs), however, the underlying mechanisms are unknown. This study aimed to elucidate the characteristics of CD4+GNLY+ T cells and their relationship with immune restoration.
Yang X +13 more
europepmc +4 more sources
Immunological Review on Non-responder Phenomenon to Hepatitis B Vaccination
Hepatitis B vaccine has been highly effective in preventing HBV infection. However, a subset of individuals fails to develop adequate protective antibodies after complete vaccination series (anti-HBs ≥ 10 mIU/mL), termed as non-responders. Non-responder phenomenon is influenced by a complex interplay of genetic, immunological, and environmental factors.
Adika Zhulhi Arjana, Ninda Devita
openaire +1 more source
Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin +17 more
wiley +1 more source
Responders vs. non-responders.
Responders vs. non-responders.
Leonid Goubergrits (147403) +11 more
core +1 more source

