Incomplete immune reconstitution in HIV/AIDS patients on antiretroviral therapy: Challenges of immunological non-responders. [PDF]
J Leukoc Biol, 2020 Abstract The morbidity and mortality of HIV type-1 (HIV-1)-related diseases were dramatically diminished by the grounds of the introduction of potent antiretroviral therapy, which induces persistent suppression of HIV-1 replication and gradual recovery of CD4+ T-cell counts.
Yang X +5 more
europepmc +4 more sources
Gut and skin microbial dysbiosis correlate with systemic inflammation and pruritus in immunological non-responders. [PDF]
Front MicrobiolIntroduction Among people living with human immunodeficiency virus (PLWH), those who exhibit immunological non-responders (INR) are highly susceptible to developing pruritus. The aim of this study was to examine the relationships among pruritus, alteration of the gut and skin microbiomes, and systemic ...
Li J, Xu L, Ding X, Qiu N, Yue J.
europepmc +2 more sources
Metformin may be a viable adjunctive therapeutic option to potentially enhance immune reconstitution in HIV-positive immunological non-responders. [PDF]
Chin Med J (Engl), 2023 Abstract Incomplete immune reconstitution remains a global challenge for human immunodeficiency virus (HIV) treatment in the present era of potent antiretroviral therapy (ART), especially for those individuals referred to as immunological non-responders (INRs), who exhibit dramatically low
Zaongo SD, Chen Y.
europepmc +4 more sources
Immunologic hypo- or non-responder in natural dengue virus infection [PDF]
Journal of Biomedical Science, 2013 Serologically defined primary dengue virus infection and/or subsequent homologous serotype infection is known to be associated with less severe disease as compared with secondary subsequent heterologous serotype infection. In geographical locales of high dengue endemicity, almost all individuals in the population are infected at some point in time and ...
Guey‐Chuen Perng +1 more
openaire +2 more sources
Higher Proportions of Circulating CXCR3+ CCR6− Tfh Cells as a Hallmark of Impaired CD4+ T-Cell Recovery in HIV-1-Infected Immunological Non-Responders [PDF]
MBioUdaykumar Ranga +1 more
exaly +2 more sources
The Dietary Inflammatory Index Is Not Associated With Gut Permeability or Biomarkers of Systemic Inflammation in HIV Immunologic Non-responders [PDF]
Frontiers in Nutrition, 2021 Immunologic non-responders (INRs) are a subset of individuals living with HIV who have suboptimal blood CD4+ T cell recovery despite effective antiretroviral therapy (ART). They are at an increased risk of serious non-AIDS co-morbidities and death, and demonstrate enhanced systemic immune activation.
Fat Malazogu +17 more
openaire +4 more sources
Differences in ASMR-15 total scores for self assessed ASMR-responders and ASMR-non-responders.
, 2023 Differences in ASMR-15 total scores for self assessed ASMR-responders and ASMR-non-responders.
Tobias Lohaus (14328798) +3 more
core +1 more source
Digital Immune Gene Expression Profiling Discriminates Allergic Rhinitis Responders from Non-Responders to Probiotic Supplementation [PDF]
, 2019 Probiotic supplementation for eight weeks with a multi-strain probiotic by individuals with allergic rhinitis (AR) reduced overall symptom severity, the frequency of medication use and improved quality of life.
Cripps, Allan W +13 more
core +1 more source
Attrition analysis between responders and non-responders.
, 2023 Attrition analysis between responders and non-responders.
Anna Wikman (352234) +3 more
core +1 more source
, 2020 ObjectiveHIV-infected individuals undergoing therapy may show an immunological-discordant response to therapy, with poor CD4+ T cells recovery, despite viral suppression below the detection limit.
Aman Sharma +3 more
core +1 more source