Results 51 to 60 of about 10,181,415 (248)

The predictive role of CD4+ cell count and CD4/CD8 ratio in immune reconstitution outcome among HIV/AIDS patients receiving antiretroviral therapy: an eight-year observation in China

BMC Immunology, 2019
Background The immune reconstitution after initiation of highly active antiretroviral therapy (HAART) among HIV-infected individuals substantially affects patients’ prognosis.
Chong-Xi Li, Yu-Ye Li, Li-Ping He, Jing Kou, Jin-Song Bai, Jun Liu, Bo Tian, Li-Juan Cao, Kun-Hua Wang, Yi-Qun Kuang   +9 more
doaj   +1 more source

Implications of accumulation of clonally expanded and senescent CD4⁺GNLY⁺ T cells in immunological non-responders of HIV-1 infection. [PDF]

Emerg Microbes Infect
Increased CD4+GNLY+ T cells have been confirmed to be inversely associated with CD4+ T cell count in immunological non-responders (INRs), however, the underlying mechanisms are unknown. This study aimed to elucidate the characteristics of CD4+GNLY+ T cells and their relationship with immune restoration.
Yang X, Zhen C, Huang H, Jiao Y, Fan X, Zhang C, Song J, Wang S, Zhou C, Yang X, Yuan J, Zhang J, Xu R, Wang FS.   +13 more
europepmc   +4 more sources

Digital Immune Gene Expression Profiling Discriminates Allergic Rhinitis Responders from Non-Responders to Probiotic Supplementation

, 2019
Probiotic supplementation for eight weeks with a multi-strain probiotic by individuals with allergic rhinitis (AR) reduced overall symptom severity, the frequency of medication use and improved quality of life.
Cripps, Allan W, Nicholas P. West, Peter K. Smith, Isolde Besseling-van der Vaart, Cox, Amanda J, Amanda J. Cox, Allan W. Cripps, Smith, Peter K, Ping Zhang, West, Nicholas P, Annabelle M. Watts, Watts, Annabelle M, Zhang, Ping, Besseling-van der Vaart, Isolde   +13 more
core   +1 more source

Physical activity “responders” vs “non-responders” after exercise training with air or oxygen in people with COPD and exercise-induced desaturation

, 2020
Aim: To evaluate changes in physical activity (PA) following exercise training on air or oxygen in people with COPD and EID. Methods: Secondary analysis of data from the "suppORT" trial was performed.
Zoe McKeough, Hill, Catherine, Regina Leung, Christine Mcdonald, Kylie Hill, Leung, Regina, Catherine Hill, Hill, Kylie, Seale, Helen, Jennifer Alison, Morris, Norman, Anne Holland, Lissa Spencer, Sue Jenkins, Annemarie Lee, Mcdonald, Christine, Norman Morris, McKeough, Zoe, Lee, Annemarie, Holland, Anne, Nola Cecins, Jenkins, Sue, Helen Seale, Alison, Jennifer, Cecins, Nola, Spencer, Lissa   +25 more
core   +1 more source

Attrition analysis between responders and non-responders.

, 2023
Attrition analysis between responders and non-responders.
Anna Wikman (352234), Björg Jónsdóttir (16436595), Inger Sundström Poromaa (10099008), Karin Stålberg (4126375)   +3 more
core   +1 more source

Gut lactate-producing bacteria promote CD4 T cell recovery on Anti-retroviral therapy in HIV-infected patients

Computational and Structural Biotechnology Journal, 2021
Anti-retroviral therapy (ART) effectively suppresses viral replication in HIV-infected patients, however CD4 + cell restoration to normal value is not achieved by 15–20% of patients who are called immune non-responders.
Wei Lyu, Qingren Meng, Jingfa Xiao, Jing Li, Jian Wang, Zhifeng Qiu, Xiaojing Song, Hua Zhu, Changjun Shao, Yanan Chu, Qian Zhou, Taisheng Li, Routy Jean-Pierre, Jun Yu, Yang Han, Yu Kang   +15 more
doaj   +1 more source

Changes in Parkinsonian gait kinematics with self-generated and externally-generated cues: a comparison of responders and non-responders

, 2020
Purpose: Rhythmic auditory stimulation such as listening to music can alleviate gait bradykinesia in people with Parkinson disease (PD) by increasing spatiotemporal gait features.
Adam P. Horin (8365497), Kerri S. Rawson (8365503), Elinor C. Harrison (8365494), Gammon M. Earhart (8365506), Peter S. Myers (8365500)   +4 more
core   +1 more source

Gut microbiota-associated non-cholesterol sterol dysregulation modulates immune reconstitution during antiretroviral therapy in people living with HIV

Microbiology Spectrum
Non-cholesterol sterol metabolism plays a crucial role in immune regulation. However, the non-cholesterol sterol profiles, its association with gut dysbiosis, and its impact on the CD4+ T cell recovery in people living with HIV (PLWH) are yet to be ...
Jingying Pan, Xuebin Tian, Kai Wu, Jia Ji, Mingqing Dong, Ting Sun, Dan Lv, Peng Yao, Longxian Lv, Hangping Yao   +9 more
doaj   +1 more source

Novel DNA methylome biomarkers associated with adalimumab response in rheumatoid arthritis patients

Frontiers in Immunology, 2023
Background and aimsRheumatoid arthritis (RA) patients are currently treated with biological agents mostly aimed at cytokine blockade, such as tumor necrosis factor-alpha (TNFα).
Ishtu Hageman, Ishtu Hageman, Femke Mol, Sadaf Atiqi, Vincent Joustra, Hilal Sengul, Peter Henneman, Ingrid Visman, Theodorus Hakvoort, Mike Nurmohamed, Gertjan Wolbink, Evgeni Levin, Evgeni Levin, Andrew Y.F. Li Yim, Andrew Y.F. Li Yim, Andrew Y.F. Li Yim, Geert D’Haens, Wouter J. de Jonge, Wouter J. de Jonge   +18 more
doaj   +1 more source

Brain serotonin and dopamine modulators, perceptual responses and endurance performance during exercise in the heat following creatine supplementation [PDF]

, 2008
Background:The present experiment examined the responses of peripheral modulators and indices of brain serotonin (5-HT) and dopamine (DA) function and their association with perception of effort during prolonged exercise in the heat after creatine (Cr ...
Liam Kilduff, Kilduff Liam P, Pitsiladis Yannis P, Liam P Kilduff, Kilduff, Liam P., Yannis P Pitsiladis, Pitsiladis, Y.P., Marios Hadjicharalambous, Hadjicharalambous, M., Kilduff, L., Pitsiladis, Yannis; id_orcid, Hadjicharalambous, Marios P., Hadjicharalambous Marios, Pitsiladis, Yannis   +13 more
core   +1 more source