Results 71 to 80 of about 10,572,916 (223)

Patients’ perceptions on non‐specific effects of acupuncture: Qualitative comparison between responders and non‐responders [PDF]

, 2022
Background: Non-specific effect of acupuncture constitutes part of the overall effect generated via clinical encounter beyond needle insertion and stimulation. It is unclear how responders and non-responders of acupuncture experience non-specific effects
Chung, Vincent C.H., Lesley Ward, Adams, Jon, Ho, Fai Fai, Cramer, Holger, Ho, Robin S.T., Holger Cramer, Fai Fai Ho, Robin S.T. Ho, Ward, Lesley, Leung, Brenda, Jon Adams, Yan Zhang, Brenda Leung, Zhang, Yan, Vincent C.H. Chung, Chung, Vincent C. H., Ho, Robin S. T.   +17 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Greater preserved baseline functional MRI connectivity in zolpidem responders compared to non-responders in patients with disorders of consciousness.

, 2019
peer reviewedIntroduction Zolpidem is commonly used as sleep inducer but is one of the few available pharmacological treatments for patients with disorders of consciousness (DOC).
Martial, Charlotte, Heine, Lizette, Bahri, Mohamed Ali, Charland-Verville, Vanessa, VANHAUDENHUYSE, Audrey, Ippoliti, Camilla, Aubinet, Charlène, Laureys, Steven, Gosseries, Olivia, Di Perri, Carol, Sanz, Leandro, Larroque, Stephen Karl, Carrière, Manon   +12 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Characteristics of responders and non-responders.

, 2018
Characteristics of responders and non-responders.
Maria Eveslage (3455072), Christina Wittkamp (5614013), Andrea U. Steinbicker (2873270), Lisa Traeger (2873267), Ines Ellermann (5614016)   +4 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Characteristics of Immunological Non-Responders in People Living with HIV at Abepura Hospital Papua

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY
Infection of Human Immunodeficiency Virus (HIV) lowers the body's immune system, especially CD4+ cells, making it more susceptible to opportunistic infections. Approximately 10-40% of People Living with HIV/AIDS (PLHIV) fail to achieve normal levels of CD4+ T cells despite continued virological suppression, a condition called Immunological Non ...
Justina Berry Sembiring, Agnes Rengga Indrati, Widya Amalia   +2 more
openaire   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Flow chart of responders and non-responders.

, 2015
Flow chart of responders and non-responders.
Thomas P. Mast (733517), Aernoud T. L. Fiolet (733513), Iris A. H. ter Horst (733514), Mirjam H. Mastenbroek (733515), Henneke Versteeg (733518), Mathias Meine (733519), Jetske van ’t Sant (733512), Maarten J. Cramer (684118), Pieter A. Doevendans (137859), Wouter M. van Everdingen (733516)   +9 more
core   +1 more source