Results 111 to 120 of about 30,755 (231)

T cell–dendritic cell immunological synapses

Current Opinion in Immunology, 2006
Dendritic cells (DCs) are myeloid lineage cells that are imprinted by their environment and that mature in response to microbial products. A crucial role of the DC is to impart this context-specific information to T cells as well as to present self and foreign MHC-peptide complexes through formation of an immunological synapse.
Dustin, M, Tseng, S, Varma, R, Campi, G
openaire   +3 more sources

Bridging metabolic syndrome and cognitive dysfunction: role of astrocytes

Frontiers in Endocrinology
Metabolic syndrome (MetS) and cognitive dysfunction pose significant challenges to global health and the economy. Systemic inflammation, endocrine disruption, and autoregulatory impairment drive neurodegeneration and microcirculatory damage in MetS.
Zihan Li, Zihan Li, Ya-yi Jiang, Ya-yi Jiang, Caiyi Long, Caiyi Long, Xi Peng, Xi Peng, Jiajing Tao, Jiajing Tao, Yueheng Pu, Yueheng Pu, Rensong Yue, Rensong Yue   +13 more
doaj   +1 more source

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells

eLife, 2019
Planar supported lipid bilayers (PSLB) presenting T cell receptor (TCR) ligands and ICAM-1 induce budding of extracellular microvesicles enriched in functional TCR, defined here as synaptic ectosomes (SE), from helper T cells.
David G Saliba, Pablo F Céspedes-Donoso, Štefan Bálint, Ewoud B Compeer, Kseniya Korobchevskaya, Salvatore Valvo, Viveka Mayya, Audun Kvalvaag, Yanchun Peng, Tao Dong, Maria-Laura Tognoli, Eric O'Neill, Sarah Bonham, Roman Fischer, Benedikt M Kessler, Michael L Dustin   +15 more
doaj   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, Volume 299, Issue 3, Page 328-348, March 2026.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Bio-communication of Plants [PDF]

, 2007
Plants communicate with a great variety of symbiotic partners, above and below ground. Constant monitoring of signals of biotic origin as well as abiotic environmental influences allows plants to generate appropriate response behavior.
Guenther Witzany
core   +1 more source

Plasmodium cellular effector mechanisms and the hepatic microenvironment [PDF]

, 2015
Plasmodium falciparum malaria remains one of the most serious health problems globally. Immunization with attenuated parasites elicits multiple cellular effector mechanisms capable of eliminating Plasmodium liver stages.
Urszula Krzych, Ute Frevert
core   +2 more sources

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

Persons Versus Brains: Biological Intelligence in Human Organisms [PDF]

, 2001
I go deep into the biology of the human organism to argue that the psychological features and functions of persons are realized by cellular and molecular parallel distributed processing networks dispersed throughout the whole body.
Steinhart, E.
core  

Common themes in centriole and centrosome movements. [PDF]

, 2013
addresses: School of Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford, OX3 0BP, UK.Copyright © 2011 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Trends in Cell Biology.
Allen, Basto, Beisson, Boisvieux-Ulrich, Boisvieux-Ulrich, Boisvieux-Ulrich, Bornens, Brugerolle, Burakov, Carreno, Chevrier, Cowan, Cowan, Dammermann, Dawe, Dawe, Dawe, Desai, Dupin, Etienne-Manneville, Etienne-Manneville, Euteneuer, Fan, Feldman, Finetti, Goldstein, Gomes, Gonczy, Gray, Griffiths, Griffiths, Gull, Helen R. Dawe, Higginbotham, Hirota, Hong, Jenkins, Jolly, Jolly, Karsenti, Kemphues, Kim, Klotz, Koonce, Kuhn, Kunda, Kunda, Lemullois, Lemullois, Lin, Ludford-Menting, Magdalena, Mahoney, Malone, Manneville, Moreira-Leite, Nejmeddine, Nigg, Palazzo, Pan, Park, Park, Pegtel, Piel, Piguet, Prigozhina, Raff, Riento, Rios, Robinson, Robinson, Rosenblatt, Roux, Ryser, Salpingidou, Schmoranzer, Scholey, Siegrist, Sonneville, Starr, Stinchcombe, Stinchcombe, Stowers, Sue Vaughan, Tabuse, Tanaka, Thery, Toyoshima, Tsai, Tsai, Tsou, Valente, Vaughan, Walczak, Wiedemann, Woolner, Worman, Wright, Yamashita, Zhang, Zhang, Zhen   +101 more
core   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

Advanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava, Lydia Herrmann, Eden Ozkan, Abhiram Kunamneni, Vinamra Swaroop, Geetika Nehra, Rohit Srivastava, Pratima Tripathi, Ken Inoki, Julie E. Goodwin   +9 more
wiley   +1 more source