Cutting Edge: The Dendritic Cell Cytoskeleton Is Critical for the Formation of the Immunological Synapse [PDF]
Monther Al‐Alwan+3 more
openalex +1 more source
The immunological synapse: integrins take the stage
Summary: Adhesive interactions play important roles in coordinating T‐cell migration and activation, specifically in the formation of the immunological synapse (IS), a specialized cell‐cell junction. Recent demonstrations show several molecules implicated in T‐cell signaling, including Vav, ADAP, and Rap‐1, have major roles in integrin regulation and ...
Sims, T, Dustin, M
openaire +4 more sources
A Beginners Guide to Systems Simulation in Immunology [PDF]
Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research.
arxiv
Immature CD4+CD8+ Thymocytes Form a Multifocal Immunological Synapse with Sustained Tyrosine Phosphorylation [PDF]
Eric Hailman+4 more
openalex +1 more source
Functional role of UNC13D in immune diseases and its therapeutic applications
UNC13 family (also known as Munc13) proteins are evolutionarily conserved proteins involved in the rapid and regulated secretion of vesicles, including synaptic vesicles and cytotoxic granules.
Van-Thanh Duong+4 more
doaj +1 more source
Membrane domains and the immunological synapse: keeping T cells resting and ready [PDF]
Michael L. Dustin
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Wiskott–Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses [PDF]
Jordan S. Orange+9 more
openalex +1 more source
Acquisition of Viral Receptor by NK Cells Through Immunological Synapse [PDF]
Julie Tabiasco+5 more
openalex +1 more source
CD5 Inhibits Signaling at the Immunological Synapse Without Impairing Its Formation [PDF]
Cédric Brossard+3 more
openalex +1 more source