Results 211 to 220 of about 462,461 (237)

Editorial: Glial cells in health and disease: impacts on neural circuits and plasticity. [PDF]

Front Cell Neurosci
Hosseini S, Thakur P, Cedeno DL, Fereidoni M, Elahdadi Salmani M.   +4 more
europepmc   +1 more source

T-cell engagers: model interrogation as a tool to quantify the interplay of relative affinity and target expression on trimer formation. [PDF]

Front Pharmacol
Lai M, Pichardo-Almarza C, Verma M, Shahinuzzaman M, Zhu X, Kimko H.   +5 more
europepmc   +1 more source

Cholinergic modulation of neural networks supports sequential and complementary roles for NREM and REM states in memory consolidation. [PDF]

PLoS Comput Biol
Satchell M, Butel-Fry E, Noureddine Z, Simmons A, Ognjanovski N, Aton SJ, Zochowski MR.   +6 more
europepmc   +1 more source

PDZ domains of PATJ facilitate immunological synapse formation to promote T cell activation. [PDF]

J Immunother Cancer
Xiong X, Wang D, Xu L, Chen S, He J, Zhang X, Fang Z, Zhang J, Li W, Zhou P.   +9 more
europepmc   +1 more source

Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse. [PDF]

Proc Natl Acad Sci U S A
McArthur HCW, Bajur AT, Iliopoulou M, Spillane KM.   +3 more
europepmc   +1 more source

Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy

Lemaître F, Mercey O, Mean I, Paulin E, Dutoit V, Rath J, Migliorini D, Arber C, Guichard P, Hamel V, Wolf B.   +10 more
europepmc   +1 more source

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Plasticity of immunological synapses.

Current Topics in Microbiology and Immunology, 2010
TCR engagement with peptide/MHC complexes displayed on the surface of the antigen-presenting cells is the crucial event in developing an adaptive immune response and occurs within specialized signaling areas named immunological synapses. Immunological synapses are diverse both in structure and function and exhibit a strikingly dynamic molecular ...
S. Valitutti, L. Dupré
semanticscholar   +4 more sources

The diversity of immunological synapses. [PDF]

Current Opinion in Immunology, 2003
Immunological synapses (ISs) are specialised signalling domains characterised by complex molecular clustering and segregation at the contact site between cells of the immune system. T lymphocytes form different ISs depending on their state of activation and on the antigen-presenting cells with which they interact. The structural features of the various
A. Trautmann, S. Valitutti
semanticscholar   +5 more sources

Harnessing the Formation of Natural Killer–Tumor Cell Immunological Synapses for Enhanced Therapeutic Effect in Solid Tumors

Advances in Materials, 2020
The formation of an immunological synapse (IS) on recognition of a cancer cell is the main mechanism underlying the natural killer (NK)‐cell‐mediated killing of tumor cells.
Sooseok Im, Donghyun Jang, G. Saravanakumar, Junseok Lee, Yeoul Kang, Yeong Mi Lee, Jaehyun Lee, Junsang Doh, Zung Yoon Yang, M. Jang, W. Kim   +10 more
semanticscholar   +1 more source

The immunological synapse

Molecular Immunology, 2002
The immunological synapse plays a central role in organising the immune system. Through their synaptic activity both T and B cells usually, but not always, acquire the information that critically determines the level and nature of the responses that they make. For T cells much of that information comes from epicrine and paracrine cell-cell interactions
N.M. Terazzini, R.J. Creusot, N.A. Mitchison   +2 more
openaire   +3 more sources