Results 221 to 230 of about 462,461 (237)
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A check on the immunological synapse
Science Signaling, 2023Blocking Nogo receptor 1 on natural killer cells enhances cell killing by stabilizing contact with target cells.
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Purinergic signaling at immunological synapses.
Journal of the Autonomic Nervous System, 2000The early studies and hypotheses of Geoffrey Burnstock catalyzed intensive characterization of roles for nucleotides and P2 nucleotide receptors in neurotransmission and neuromodulation. These latter analyses have focused on the mechanisms of nucleotide release and action in the microenvironments of nerve endings and synapses.
G. Dubyak
semanticscholar +4 more sources
In Analysis, 2010
Confocal Raman micro-spectroscopy (CRMS) was used to measure spectral images of immunological synapse formation between dendritic and T cells without using molecular labels or other invasive procedures.
A. Zoladek +6 more
semanticscholar +1 more source
Confocal Raman micro-spectroscopy (CRMS) was used to measure spectral images of immunological synapse formation between dendritic and T cells without using molecular labels or other invasive procedures.
A. Zoladek +6 more
semanticscholar +1 more source
Signaling and the Immunological Synapse
2010This chapter deals with T cell activation and immunological synapses. It begins with a brief summary of T cell biology to put a discussion of immune synapses into a broader context because the study of immunological synapses addresses issues pertaining mainly to the field of cellular immunology.
Giurisato, Emanuele, Shaw, Andrey S.
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Signaling Amplification at the Immunological Synapse
2009The immunological synapse is a dynamic structure, formed between a T cell and one or more antigen-presenting cells, characterized by lipid and protein segregation, signaling compartmentalization, and bidirectional information exchange through soluble and membrane-bound transmitters.
VIOLA, ANTONELLA +2 more
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The Immunological Synapse and Rho GTPases [PDF]
, 2005 Rho GTPases are molecular switches controlling a broad range of cellular processes including lymphocyte activation. Not surprisingly, Rho GTPases are now recognized as pivotal regulators of antigen-specific T cell activation by APCs and immunological synapse formation.
Marcel Deckert, S. Le Bras, Cheol Moon
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Archivum immunologiae et therapiae experimentalis, 2004
The induction of a proper adaptive immune response is dependent on the correct transfer of information between antigen-presenting cells (APCs) and antigen-specific T cells. Defects in information transfer may result in the development of diseases, e.g. immunodeficiencies and autoimmunity.
Klemmensen, Thomas +2 more
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The induction of a proper adaptive immune response is dependent on the correct transfer of information between antigen-presenting cells (APCs) and antigen-specific T cells. Defects in information transfer may result in the development of diseases, e.g. immunodeficiencies and autoimmunity.
Klemmensen, Thomas +2 more
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Annual Review of Cell and Developmental Biology, 2008
The immunological synapse was initially defined as a stable cell-cell junction composed of three concentric supramolecular activation clusters (SMACs) enriched in particular components: a central SMAC with clustered antigen receptors and kinases, a ...
Michael Loran Dustin
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The immunological synapse was initially defined as a stable cell-cell junction composed of three concentric supramolecular activation clusters (SMACs) enriched in particular components: a central SMAC with clustered antigen receptors and kinases, a ...
Michael Loran Dustin
semanticscholar +1 more source
Mitochondria at the Immunological Synapse
Science's STKE, 2007Quintana et al . noted that beads coated with antibodies to CD3, a constituent of the T cell receptor (TCR) complex, produced a larger and more sustained calcium signal in the Jurkat T cell line and primary human T cells than did the same antibodies in solution.
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T-Cell Activation and Immunologic Synapse
Immunologic Research, 2005The focus of my laboratory is in three areas. The first area is our long-standing interest in the mechanics of T-cell activation. In addition to our interest in protein phosphorylation mediated by T-cell receptor engagement, we have been interested in defining the function of the immunologic synapse.
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