Results 41 to 50 of about 30,755 (231)

Chromogranin A in the olfactory system of the rat [PDF]

, 1990
The olfactory bulb of the rat contains chromogranin A at a similar level as the adrenal gland or the hypophysis as revealed by immunoblots. Olfactory chromogranin A also displays the same size as chromogranin A of endocrine cells.
Baker, Bulenda, Bööj, Doolittle, Efendic, Ehrlich, Fasciotto, Forss-Petter, Gerdes, Gorr, Halász, Helle, Iacangelo, Kaplan, Kawakubo, Ley, Lizardi, Nolan, O'Connor, O'Connor, O'Connor, Parmer, Reiffen, Reiffen, Ruppert, Schilling, Schmid, Simon, Simon, Somogyi, Sternberger, Switzer, Volknandt   +32 more
core   +1 more source

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation. [PDF]

, 2018
Interactions between EphB4 receptor tyrosine kinases and their membrane-bound ephrin-B2 ligands on apposed cells play a regulatory role in neural stem cell differentiation.
Chung, Jean, Dong, Meimei, Groves, Jay, Lee, Young, SCHAFFER, David, Spelke, Dawn, Yu, Cheng-Han   +6 more
core   +2 more sources

The Role of the Immunological Synapse in Differential Effects of APC Subsets in Alloimmunization to Fresh, Non-stored RBCs

Frontiers in Immunology, 2018
Background: Each year, over 5 million red blood cell (RBC) transfusions are administered to patients in the USA. Despite the therapeutic benefits of RBC transfusions, there are associated risks.
Amanda L. Richards, Kathryn Sheldon, Xiaoping Wu, David R. Gruber, Krystalyn E. Hudson, Krystalyn E. Hudson   +5 more
doaj   +1 more source

Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease [PDF]

, 2019
Alzheimer’s disease currently lacks treatment options that effectively reverse the biological/anatomical pathology and cognitive deficits associated with the disease.
Burris, Thomas P, Farr, Susan A, Kermath, Bailey A, Morley, John E, Musiek, Erik S, Niehoff, Michael, Roby, Deborah A, Ruiz, Fernanda, Voorhees, Jaymie R, Zhang, Jinsong   +9 more
core   +3 more sources

A potential prognostic marker for hematologic neoplasms: CD58

Frontiers in Oncology
CD58 is a glycoprotein receptor widely distributed on histiocytes that binds to CD2, that takes part in constituting the Immunological Synapses (IS) and activating T/NK cells.
Jiajia Cao, Yurong Zhang, Ningning Yue, Shuzhen Xiong, Shuni Zhang, Chongyang Wu   +5 more
doaj   +1 more source

Materials and System Design for Self‐Decision Bioelectronic Systems

Advanced Materials, EarlyView.
This review highlights how self‐decision bioelectronic systems integrate sensing, computation, and therapy into autonomous, closed‐loop platforms that continuously monitor and treat diseases, marking a major step toward intelligent, self‐regulating healthcare technologies.
Qiankun Zeng, Hong Liu, Yongheng Zhang, Youbin Zheng, Xuyin Ding, Mengni Zhu, Guoyue Shi, Yan Wang, Hossam Haick, Min Zhang   +9 more
wiley   +1 more source

Down regulation of genes involved in T cell polarity and motility during the induction of heart allograft tolerance by allochimeric MHC I. [PDF]

PLoS ONE, 2009
BACKGROUND:The allochimeric MHC class I molecule [alpha1h1/u]-RT1.Aa that contains donor-type (Wistar Furth, WF; RT1u) epitopes displayed on recipient-type (ACI, RT1a) administered in conjunction with sub-therapeutic dose of cyclosporine (CsA) induces ...
Wojciech Lisik, Neelam Tejpal, Yongquan Gong, T Spencer Skelton, Malathesh Ganachari, Eric G Bremer, Malgorzata Kloc, Rafik M Ghobrial   +7 more
doaj   +1 more source

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

The dendritic cell side of the immunological synapse

Biomolecular Concepts, 2016
Immune responses are initiated by the interactions between antigen-presenting cells (APCs), such as dendritic cells (DCs), with responder cells, such as T cells, via a tight cellular contact interface called the immunological synapse.
Verboogen Danielle R.J., Dingjan Ilse, Revelo Natalia H., Visser Linda J., ter Beest Martin, van den Bogaart Geert   +5 more
doaj   +1 more source

Regulatory T cells diminish transmission of HIV from Dendritic cells to conventional CD4+ T cells

Frontiers in Immunology, 2014
Formation of immunological synapses between dendritic cells (DC) and conventional CD4+ T cells (Tcon) is critical for productive immune responses. However, when DCs are HIV-infected such synapses are critical to establish HIV infection.
Maria Eugenia Moreno-Fernandez, Maria Eugenia Moreno-Fernandez, Jara J Joedicke, Claire Anne Chougnet   +3 more
doaj   +1 more source