Results 61 to 70 of about 1,328,564 (298)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

The Function of the TGFβ Signaling Pathway in Connective Tissue Diseases: From Biology to Clinical Application

open access: yesJournal of Inflammation Research
Simin Yuan,1 Wen Zhu,2 Yue Wang,1,2 Lili Yu1,3,4 1Faculty of Chinese Medicine, Macau University of Science and Technology, Macau, People’s Republic of China; 2Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of ...
Yuan S, Zhu W, Wang Y, Yu L
doaj  

Selected abstracts of the third international congress of Immunology, Asthma and Allergy 2017, Iran

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2018
The third congress of Immunology, Asthma and Allergy (ICIAA) took place at the Imam Hall of Imam Khomeini Hospital, 15-17 February 2017. This congress was held under the presidency of Prof.
International congress Immunology, Asthma and Allergy
doaj  

Strengthening immunology literacy: an adaptable curricular framework for enhancing undergraduate immunology education

open access: yesFrontiers in Education
The rapidly expanding knowledge base in immunology and its increasing significance in multiple research areas and healthcare underscore the need for more comprehensive undergraduate curricula that allow students to engage deeply with immunology-based ...
Chad R. Sethman, Kelly J. R. Collins
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

VETERINARY IMMUNOLOGY

open access: yesМедицинская иммунология, 2015
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Article Editorial
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

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