Results 191 to 200 of about 10,784 (232)
Immunometabolism in the Aging Heart
Journal of the American Heart AssociationStructural, functional, and molecular‐level changes in the aging heart are influenced by a dynamic interplay between immune signaling and cellular metabolism that is referred to as immunometabolism.
Kranti A Mapuskar +2 more
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An integrated toolbox to profile macrophage immunometabolism
Cell Reports Methods, 2022 Macrophages are dynamic immune cells that can adopt several activation states. Fundamental to these functional activation states is the regulation of cellular metabolic processes.
Sanne G S Verberk +2 more
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How Changes in the Nutritional Landscape Shape Gut Immunometabolism
Nutrients, 2021 Cell survival, proliferation and function are energy-demanding processes, fuelled by different metabolic pathways. Immune cells like any other cells will adapt their energy production to their function with specific metabolic pathways characteristic of ...
Jian Tan, Duan Ni, Rosilene V Ribeiro
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Immunometabolism in the pathogenesis of asthma
Immunology, 2023AbstractBronchial asthma is a heterogeneous disease characterised by chronic airway inflammation. A variety of immune cells such as eosinophils, mast cells, T lymphocytes, neutrophils and airway epithelial cells are involved in the airway inflammation and airway hyperresponsiveness in asthma pathogenesis, resulting in extensive and variable reversible ...
Ziwen Qin +6 more
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Metabolomics, Lipidomics, and Immunometabolism
2021Metabolomics, lipidomics, and the study of cellular metabolism are gaining increasing interest particularly in the field of immunology, since the activation and effector functions of immune cells are profoundly controlled by changes in cellular metabolic asset.
Carbone F. +8 more
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Immunometabolism and autoimmunity
Immunology & Cell Biology, 2016A continuous increase in the prevalence of autoimmune diseases is to be expected in the aging societies worldwide. Autoimmune disorders not only cause severe disability and chronic pain, but also lead to considerable socio‐economic costs. Given that the current treatment options are not curative, have substantial side effects and a high percentage of ...
Jenny, Freitag +3 more
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Interplay of Immunometabolism and Epithelial–Mesenchymal Transition in the Tumor Microenvironment
International Journal of Molecular Sciences, 2021 Epithelial–mesenchymal transition (EMT) and metabolic reprogramming in cancer cells are the key hallmarks of tumor metastasis. Since the relationship between the two has been well studied, researchers have gained increasing interest in the interplay of ...
Muh-Hwa Yang, Yang Muh-Hwa
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Editorial overview: Immunometabolism
Current Opinion in Pharmacology, 2021Energy metabolism is a key determinant of the immune response. Classical biochemistry has precisely dissected intracellular metabolic pathways, highlighting how cells adapt to different tasks requiring increasing energy demand. However, until about two decades ago, most immunologists assumed that immune cells were a realm apart that did not comply with
Di Virgilio F., Borges da Silva H.
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