Results 191 to 200 of about 79,221 (241)

JAK Inhibition in STAT1 Gain-of-Function-Associated Histoplasmosis and HLH. [PDF]

open access: yesJ Clin Immunol
Patel J   +4 more
europepmc   +1 more source

Akkermansia muciniphila enhances chicken resistance to infectious bronchitis virus by boosting GABA synthesis and suppressing the NF‐κB inflammatory pathway

open access: yesiMetaOmics, EarlyView.
Infectious bronchitis virus (IBV) represents a major threat to poultry production, with current control strategies offering limited protection. In this study, we demonstrate gut microbiome is a critical determinant of IBV resistance using fecal microbiota transplantation.
Ouyang Peng   +22 more
wiley   +1 more source

Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection

open access: yesiMeta, EarlyView.
DMC/CUR antagonize viral hijacking of host nucleic acid resources and finely regulate the induction and effector phases of the type I interferon (IFN‐I) pathway through the CRYAB‐RBM26 axis. This molecular axis serves as a key downstream regulator for DMC/CUR activation of the IFN‐I pathway.
Tingting Chen   +18 more
wiley   +1 more source

Analysis of key immune genes in mesenchymal stem cells in a 3D environment. [PDF]

open access: yesAm J Stem Cells
Li H   +8 more
europepmc   +1 more source

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

open access: yesiMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu   +7 more
wiley   +1 more source

Intratumoral bacteria engineered for tumor therapy

open access: yesInterdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang   +7 more
wiley   +1 more source

Reply. [PDF]

open access: yesJ Vasc Surg Venous Lymphat Disord
Fukaya E.
europepmc   +1 more source

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