Results 121 to 130 of about 59,841 (273)
Pathogenesis of hidradenitis suppurativa: From susceptibility to chronicity
Journal of the European Academy of Dermatology and Venereology, EarlyView.This review describes hidradenitis suppurativa as a heterogeneous disorder in which genetic susceptibility, epithelial dysfunction, environmental exposures, immune activation and microbial ecology converge differently across patients and disease stages.
Kelsey R. van Straalen +5 more
wiley +1 more source
Immunopathology of sarcoidosis.
Iranian journal of allergy, asthma, and immunology, 2014 The immunopathology of sarcoidosis remains elusive despite years of research into this multiorgan disease.However, recent studies have provided new insights into the genetics and immune components involved in the clinical manifestation of the disease.
Mortaz, E +4 more
openaire +3 more sources
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
A complex immunological idiotypic network for maintenance of tolerance
Frontiers in Immunology, 2014 Véronique eTHOMAS-VASLIN +2 more
doaj +1 more source
Novel insights into double-stranded RNA-mediated immunopathology
Recent progress in human and mouse genetics has transformed our understanding of the molecular mechanisms by which recognition of self double-stranded RNA (self-dsRNA) causes immunopathology.
de Reuver, Richard, Maelfait, Jonathan
core +1 more source
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Immunopathology of Dirofilaria immitis Infection
, 2007 Heartworm disease caused by Dirofilaria immitis affects canine and feline hosts, with infections occasionally being reported in humans. Studies have shown that both dirofilarial antigens and those derived from its bacterial endosymbiont Wolbachia ...
F. Simon +7 more
core +1 more source
Oral Diseases, EarlyView.ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang +5 more
wiley +1 more source
Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders
Oral Diseases, EarlyView.ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz +6 more
wiley +1 more source
Studies on the immunopathology of tuberculosis [PDF]
, 1998 In this presentation, two aspects concerning the immunopathology of tuberculosis at the microanatomical level will be considered. The material for this presentation is drawn from our studies on tuberculous lymphadenitis (450 cases) and skin ...
Ramanathan, V D
core +1 more source