Results 141 to 150 of about 59,841 (273)
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Immunopathology and virulence evolution in rodent malaria
From an evolutionary perspective, natural selection is expected to maximize transmission to new hosts. If a live, mobile host often benefits parasite transmission, the question arises as to why malaria parasites are virulent?
Long, Gráinne Helen +3 more
core
Mmp‐8 deficiency during H1N1 influenza infection enhances Type I interferon responses, necroptosis‐associated signaling, and adaptive immunity, leading to lower lung viral burden and improved survival, but also amplifies inflammatory lung injury. ABSTRACT Matrix metalloproteinase‐8 (MMP‐8) regulates inflammatory responses, but its contributions to the ...
Xiaoyun Wang +4 more
wiley +1 more source
Editorial: Immunopathology of Chronic Bacterial and Viral Diseases Prevalent in Latin America
Rosana Pelayo +2 more
doaj +1 more source
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati +10 more
wiley +1 more source
Jablonska, Stefania, Beutner, Ernst H.
openaire +2 more sources
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
Reclaiming Anatomy as Method: From Morphological Reasoning to Clinical Relevance
ABSTRACT In recent decades, molecular biology and omics technologies have profoundly reshaped biomedical research, with genomics, proteomics, and other high‐throughput approaches dominating scientific agendas and funding priorities. Within this molecular paradigm, however, the anatomical sciences face an epistemic and institutional tension: morphology,
Katia Cortese, Marco Frascio
wiley +1 more source
Investigating CD8 T Cell Exhaustion in Chronic LCMV Infection by Flow Cytometry
Abstract CD8 T cells and the process of T cell exhaustion are central topics in both basic immunology and translational research, including clinical applications. Here, we provide a comprehensive, step‐by‐step guide to investigate CD8 T cells in murine in vivo lymphocytic choriomeningitis virus (LCMV) infection models.
Dominique Stark +5 more
wiley +1 more source

