Results 131 to 140 of about 59,841 (273)

Combined Posterolateral Corner and Proximal Tibiofibular Joint Anatomic Reconstruction: A Surgical Strategy for Complex Posterolateral Knee Instability

open access: yesOrthopaedic Surgery, EarlyView.
A novel anatomic surgical strategy for simultaneous stabilization of the posterolateral corner and proximal tibiofibular joint is described. By using independent graft tensioning and angle‐specific fixation, this reproducible technique successfully restores global knee stability, addressing a complex injury pattern previously lacking a standardized ...
Javier Faus‐Cotino   +4 more
wiley   +1 more source

Immunopathological Mechanisms [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1974
openaire   +2 more sources

Pediatric Lichen Planus Pemphigoides in a Child With Sickle Cell Disease: Cyclosporine Induction and Dupilumab Maintenance

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Lichen planus pemphigoides (LPP) is a rare autoimmune subepidermal blistering disorder that combines lichenoid lesions of lichen planus with immunopathologic features of pemphigoid disease. We report an 8‐year‐old boy with homozygous sickle cell disease and severe atopic dermatitis who developed diffuse pruritic violaceous papules followed by ...
Yumeng T. Engelking   +3 more
wiley   +1 more source

Type I interferons prevent cell death and liver immunopathology in Mouse Hepatitis Virus infected mice 2333173

open access: yes
Introduction Type I interferons (IFNs) hinder the viral replication process and regulate the immune system to mount an antiviral response.
Fatemeh Vahedi, Alyssa Mark, Ali Ashkar
core   +1 more source

The role of acquired host immunity in periodontal diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane   +2 more
wiley   +1 more source

Genetic risk variants implicate impaired maintenance and repair of periodontal tissues as causal for periodontitis—A synthesis of recent findings

open access: yesPeriodontology 2000, EarlyView.
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer   +4 more
wiley   +1 more source

Factors influencing the effectiveness of surgical therapy of peri‐implantitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Surgical therapy is required in the majority of peri‐implantitis cases due to the inconsistent efficacy of non‐surgical approaches. Although surgical treatment generally offers higher predictability, reported success rates vary widely.
Ausra Ramanauskaite   +3 more
wiley   +1 more source

Metabolic reprogramming of the immune response in periodontitis

open access: yesPeriodontology 2000, EarlyView.
Abstract Objective Periodontitis, a highly prevalent chronic inflammatory disease, is characterized by the progressive destruction of the tooth‐supporting tissues, ultimately causing tooth loss. In recent years, the emerging field of immunometabolism has revealed that immune cell function is tightly regulated by intracellular metabolic pathways that ...
Rafael Scaf de Molon   +3 more
wiley   +1 more source

Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira   +6 more
wiley   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1897-1921, November 2026.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy